Obesity has been reported to be associated withmany diseases. However, common obesity-inducedbiological processes have not been evaluated acrossthese diseases. We identified genes associated withobesity and obesity-re...Obesity has been reported to be associated withmany diseases. However, common obesity-inducedbiological processes have not been evaluated acrossthese diseases. We identified genes associated withobesity and obesity-related diseases, and used them toconstruct protein-protein interaction networks. We alsoanalyzed gene ontology (GO) in those genes over-lapping between obesity and disease. Our work iden-tifies gene modules common to obesity and obesity-related diseases, which can provide a basis for under-standing the process of how obesity induces disease.展开更多
基金supported by the Key Project of Hebei North University(No.120177)the Key Project of Medical Science Research in Hebei Province(No.20150061),China
文摘Obesity has been reported to be associated withmany diseases. However, common obesity-inducedbiological processes have not been evaluated acrossthese diseases. We identified genes associated withobesity and obesity-related diseases, and used them toconstruct protein-protein interaction networks. We alsoanalyzed gene ontology (GO) in those genes over-lapping between obesity and disease. Our work iden-tifies gene modules common to obesity and obesity-related diseases, which can provide a basis for under-standing the process of how obesity induces disease.