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Aberrant p16 promoter hypermethylation in bronchial mucosae as a biomarker for the early detection of lung cancer 被引量:5
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作者 XIE Guang-shun HOU Ai-rong +2 位作者 LI Long-yun GAO Yan-ning CHENG Shu-jun 《Chinese Medical Journal》 SCIE CAS CSCD 2006年第17期1469-1472,共4页
Lung cancer is the leading cause of cancer related death in the world and its mortality could be greatly reduced by diagnosis and treatment in its early stages. Effective tools for the early detection of lung cancer a... Lung cancer is the leading cause of cancer related death in the world and its mortality could be greatly reduced by diagnosis and treatment in its early stages. Effective tools for the early detection of lung cancer and its high risk factors remain a major challenge. Biomarkers that detect lung cancer in its early stages or identify its pretumour lesions, enabling early therapeutic intervention, would be invaluable to improve its dismal prognosis. 展开更多
关键词 p16 gene HYPERMETHYLATION bronchial mucosa BIOMARKER lung neoplasm
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