Highly porous ultrafine electrospun scaffolds,gelatin/poly(L-lactic acid)(PLLA) and chitosan/PLLA were prepared by blending gelatin and PLLA,chitosan and PLLA respectively.The biocompatibilities of these scaffolds wer...Highly porous ultrafine electrospun scaffolds,gelatin/poly(L-lactic acid)(PLLA) and chitosan/PLLA were prepared by blending gelatin and PLLA,chitosan and PLLA respectively.The biocompatibilities of these scaffolds were assessed by attachment,proliferation and viability of cells on them.The results indicated that over 30%WI-38 cells could attach to the gelatin/PLLA and chitosan/PLLA scaffolds at 2 h after seeding,while the attachment of the cells was only 15%on PLLA scaffolds.Both gelatin/PLLA and chitosan/PLLA scaffolds also exhibited a very good ability for proliferation of WI-38 cells.Cell growth on the gelatin/PLLA and chitosan /PLLA scaffolds showed dramatic improvement,indicating a much better biocompatibility in the blends contributed by gelatin and chitosan.3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay also demonstrated gelatin/PLLA showed better ability to enhance the growth and functions of the cells.These assays suggest that the electrospun gelatin/PLLA and chitosan/PLLA scaffolds are promising biomaterials with great biocompatibility for the development of skin tissue engineering.展开更多
PEDOT,or poly(3,4-ethylenedioxythiophene),is among the most successful conducting polymer products because of its stable conductivity,colloidal processability,and rich assembly behavior.Since the very first patents on...PEDOT,or poly(3,4-ethylenedioxythiophene),is among the most successful conducting polymer products because of its stable conductivity,colloidal processability,and rich assembly behavior.Since the very first patents on PEDOT filed in 1988,the material has been widely explored for decades in many applications.In this review,a comprehensive summary on the synthesis,processing and post-treatment of PEDOT will be presented for the sake of the discussion on PEDOT and its nanocomposites for energy storage.Knowing what PEDOT lends itself to the electrode materials is of importance to the rational design of energy storage devices that maximize the real-world performance.Based on these discussions,a roadmap for the development of PEDOT as promising multifunctional electrode component is presented.展开更多
基金the Project of the Science and Technology Commission of Shanghai Municipality (No.Ilnm0505100)the China Postdoctoral Science Foundation(No.2012M510116)the Fundamental Research Funds for the Central Universities (No.0500219160)
文摘Highly porous ultrafine electrospun scaffolds,gelatin/poly(L-lactic acid)(PLLA) and chitosan/PLLA were prepared by blending gelatin and PLLA,chitosan and PLLA respectively.The biocompatibilities of these scaffolds were assessed by attachment,proliferation and viability of cells on them.The results indicated that over 30%WI-38 cells could attach to the gelatin/PLLA and chitosan/PLLA scaffolds at 2 h after seeding,while the attachment of the cells was only 15%on PLLA scaffolds.Both gelatin/PLLA and chitosan/PLLA scaffolds also exhibited a very good ability for proliferation of WI-38 cells.Cell growth on the gelatin/PLLA and chitosan /PLLA scaffolds showed dramatic improvement,indicating a much better biocompatibility in the blends contributed by gelatin and chitosan.3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay also demonstrated gelatin/PLLA showed better ability to enhance the growth and functions of the cells.These assays suggest that the electrospun gelatin/PLLA and chitosan/PLLA scaffolds are promising biomaterials with great biocompatibility for the development of skin tissue engineering.
基金supported by the National Natural Science Foundation of China(No.51673108)the National Key R&D Program of China(No.2016YFA0200202).
文摘PEDOT,or poly(3,4-ethylenedioxythiophene),is among the most successful conducting polymer products because of its stable conductivity,colloidal processability,and rich assembly behavior.Since the very first patents on PEDOT filed in 1988,the material has been widely explored for decades in many applications.In this review,a comprehensive summary on the synthesis,processing and post-treatment of PEDOT will be presented for the sake of the discussion on PEDOT and its nanocomposites for energy storage.Knowing what PEDOT lends itself to the electrode materials is of importance to the rational design of energy storage devices that maximize the real-world performance.Based on these discussions,a roadmap for the development of PEDOT as promising multifunctional electrode component is presented.