A potent cytotoxic bufadienolide orthoacetate has been Isolated from Bryophyllum pinnatum. Baaed on spectral study methods, its structure was identified as bersaldegenin 1,3, 5-orthoacetate.
Three stilbene tetramers, carasinols AC (13), along with three known substances, leachianol C, cararosinol A and stenophyllol B, were isolated from the roots of Caragana sinica. Their structures were elucidated by spe...Three stilbene tetramers, carasinols AC (13), along with three known substances, leachianol C, cararosinol A and stenophyllol B, were isolated from the roots of Caragana sinica. Their structures were elucidated by spec-troscopy. It was found that compounds isolated except for stenophyllol B stimulated the proliferation of cultured osteoblasts.展开更多
A new antifungal antibiotic, fusarielin E, was isolated from the marine-derived fungus Fusarium sp. Its structure was established on the basis of various NMR spectroscopic analyses and HR-FAB-MS. Fusarielin E displaye...A new antifungal antibiotic, fusarielin E, was isolated from the marine-derived fungus Fusarium sp. Its structure was established on the basis of various NMR spectroscopic analyses and HR-FAB-MS. Fusarielin E displayed significant biological activity against Pyricularia oryzae.展开更多
A convenient and efficient method for the highly regioselecfive synthesis of indene derivatives 4 and 5 from tetraaryl substituted 1,3-butadienes 3 was described. The method involves an intramolecular Friedel-Crafts c...A convenient and efficient method for the highly regioselecfive synthesis of indene derivatives 4 and 5 from tetraaryl substituted 1,3-butadienes 3 was described. The method involves an intramolecular Friedel-Crafts cyclization and a corresponding double-bond positional shift of isomers 4 and 5 in the presence of different Lewis acids under mild conditions with higher than 90% yields.展开更多
文摘A potent cytotoxic bufadienolide orthoacetate has been Isolated from Bryophyllum pinnatum. Baaed on spectral study methods, its structure was identified as bersaldegenin 1,3, 5-orthoacetate.
基金Project supported by the National Natural Science Foundation of China (No. 39270800).
文摘Three stilbene tetramers, carasinols AC (13), along with three known substances, leachianol C, cararosinol A and stenophyllol B, were isolated from the roots of Caragana sinica. Their structures were elucidated by spec-troscopy. It was found that compounds isolated except for stenophyllol B stimulated the proliferation of cultured osteoblasts.
基金financially supported by the National Natural Science Foundation of China(no.30371680).
文摘A new antifungal antibiotic, fusarielin E, was isolated from the marine-derived fungus Fusarium sp. Its structure was established on the basis of various NMR spectroscopic analyses and HR-FAB-MS. Fusarielin E displayed significant biological activity against Pyricularia oryzae.
基金Project supported by the National Natural Science Foundation of China （No, 203900506） and the Shanghai Municipal Committee of Science and Technology （Nos, 05JC14057, 054319901）,
文摘A convenient and efficient method for the highly regioselecfive synthesis of indene derivatives 4 and 5 from tetraaryl substituted 1,3-butadienes 3 was described. The method involves an intramolecular Friedel-Crafts cyclization and a corresponding double-bond positional shift of isomers 4 and 5 in the presence of different Lewis acids under mild conditions with higher than 90% yields.
