The title compound, (1α,6β, 11β,14α)-1,7:6,20-diepoxy-6,1 1-dihydroxy- 6,7-secoent- kaur- 16-ene-7,15-dione- 14-acetate (macrocalyxin J), is a diterpenoid which was isolated from the leaves of Rabdosia macroc...The title compound, (1α,6β, 11β,14α)-1,7:6,20-diepoxy-6,1 1-dihydroxy- 6,7-secoent- kaur- 16-ene-7,15-dione- 14-acetate (macrocalyxin J), is a diterpenoid which was isolated from the leaves of Rabdosia macrocalyx and characterized by single-crystal X-ray diffraction. It crystallizes in orthorhombic, space group P212121 with α= 9.3608(8), b = 14.9787(12), c = 15.5750(13) A, Z = 4, V = 2183.8(3) A^3, C22H30O9, Mr= 438.46, Dc= 1.334 g/m^3,μ(MoKα) = 0.103 mm^-1, F(000) = 936, the final R = 0.0532 and wR = 0.1262 for 2252 observed reflections (I 〉 2σ(I)). In the molecule, three six-membered rings adopt chair, boat and slightly distorted boat conformations, respectively, while both five-membered rings have approximate envelope conformations.展开更多
基金the National Natural Science Foundation of China (No. 20472073)the Natural Science Foundation of Zhejiang Province (No. Y404357)
文摘The title compound, (1α,6β, 11β,14α)-1,7:6,20-diepoxy-6,1 1-dihydroxy- 6,7-secoent- kaur- 16-ene-7,15-dione- 14-acetate (macrocalyxin J), is a diterpenoid which was isolated from the leaves of Rabdosia macrocalyx and characterized by single-crystal X-ray diffraction. It crystallizes in orthorhombic, space group P212121 with α= 9.3608(8), b = 14.9787(12), c = 15.5750(13) A, Z = 4, V = 2183.8(3) A^3, C22H30O9, Mr= 438.46, Dc= 1.334 g/m^3,μ(MoKα) = 0.103 mm^-1, F(000) = 936, the final R = 0.0532 and wR = 0.1262 for 2252 observed reflections (I 〉 2σ(I)). In the molecule, three six-membered rings adopt chair, boat and slightly distorted boat conformations, respectively, while both five-membered rings have approximate envelope conformations.