A 3-year-old boy presented with bluish patch and scattered blue spots on the left side of his face.After several sessions of laser treatment,the azury patch in the periorbital area became even darker.Histopathology sh...A 3-year-old boy presented with bluish patch and scattered blue spots on the left side of his face.After several sessions of laser treatment,the azury patch in the periorbital area became even darker.Histopathology showed many bipolar,pigment-laden dendritic cells scattered in the papillary and upper reticular dermis.Immunohistochemically,these cells were positive for S100,SOX-10,melan-A,P16,and HMB-45.The positive rate of Ki-67 was less than 5%.Finally,the lesion was diagnosed with nevus of Ota concurrent with common blue nevus.Therefore,for cases of the nevus of Ota with poor response to laser treatment,the possible coexisting diseases should be suspected.展开更多
Acne scars are caused by inflammatory reactions,infections,and improper handling of acne lesions.Such scars have a high incidence and are difficult to treat.There are many methods currently used to treat acne scars,in...Acne scars are caused by inflammatory reactions,infections,and improper handling of acne lesions.Such scars have a high incidence and are difficult to treat.There are many methods currently used to treat acne scars,including medications,photoelectric technology,surgery,filling,chemical peeling,traditional Chinese medicine,biotherapy,and microneedle therapy,and many new methods are constantly emerging.However,there are still many issues,such as the lack of high-quality clinical studies,non-uniform treatment methods,and unsatisfactory therapeutic effects.The selection of appropriate methods for the comprehensive treatment of different types of acne scars at different stages in clinical practice remains challenging and is a research topic of great interest.From the perspective of evidence-based medicine,this consensus aims to provide a reference for the treatment of acne scars in clinical practice.展开更多
基金This study was funded by the CAMS Innovation Fund for Medical Sciences(CIFMS-2021-I2M-1-001)National Natural Science Foundation of China(82103705).
文摘A 3-year-old boy presented with bluish patch and scattered blue spots on the left side of his face.After several sessions of laser treatment,the azury patch in the periorbital area became even darker.Histopathology showed many bipolar,pigment-laden dendritic cells scattered in the papillary and upper reticular dermis.Immunohistochemically,these cells were positive for S100,SOX-10,melan-A,P16,and HMB-45.The positive rate of Ki-67 was less than 5%.Finally,the lesion was diagnosed with nevus of Ota concurrent with common blue nevus.Therefore,for cases of the nevus of Ota with poor response to laser treatment,the possible coexisting diseases should be suspected.
文摘Acne scars are caused by inflammatory reactions,infections,and improper handling of acne lesions.Such scars have a high incidence and are difficult to treat.There are many methods currently used to treat acne scars,including medications,photoelectric technology,surgery,filling,chemical peeling,traditional Chinese medicine,biotherapy,and microneedle therapy,and many new methods are constantly emerging.However,there are still many issues,such as the lack of high-quality clinical studies,non-uniform treatment methods,and unsatisfactory therapeutic effects.The selection of appropriate methods for the comprehensive treatment of different types of acne scars at different stages in clinical practice remains challenging and is a research topic of great interest.From the perspective of evidence-based medicine,this consensus aims to provide a reference for the treatment of acne scars in clinical practice.
