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A case of Klinefelter's syndrome with type 1 diabetes mellitus 被引量:6
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作者 CAI Xiao-pin ZHAO Li +3 位作者 MAO Min YANG Zhao-jun XING Xiao-yan LI Guang-wei 《Chinese Medical Journal》 SCIE CAS CSCD 2012年第5期937-940,共4页
Klinefelter's syndrome (KS) is the most common sex chromosome disease in men. Classical features of the syndrome include a eunuchoidal body habitus, small testes and hypergonadotrophic hypogonadism. There has been ... Klinefelter's syndrome (KS) is the most common sex chromosome disease in men. Classical features of the syndrome include a eunuchoidal body habitus, small testes and hypergonadotrophic hypogonadism. There has been an increased risk of diabetes mellitus and autoimmune disease for KS patients. This paper reports a case of KS in association with type 1 diabetes mellitus. The patient was a 21-year-old man, who has been confirmed by absolute insulin deficiency and positive IA-2 autoantibody. The hyperinsulinemic euglycemic clamp test indicated his insulin sensitivity in normal range, and his blood glucose was controlled well by the insulin therapy. 展开更多
关键词 Klinefelter's syndrome type 1 diabetes mellitus AUTOIMMUNE
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