In this issue of Cellular&Molecular Immunology,Hou and coworkers provide novel insights into glucocorticoid(GC)treatment refractoriness in immune thrombocytopenia(ITP),reporting that myeloid-derived suppressor cel...In this issue of Cellular&Molecular Immunology,Hou and coworkers provide novel insights into glucocorticoid(GC)treatment refractoriness in immune thrombocytopenia(ITP),reporting that myeloid-derived suppressor cells(MDSCs)contribute to GC resistance in ITP via impairments in their glucocorticoid receptor(GR)expression and mitochondrial metabolism[1].展开更多
文摘In this issue of Cellular&Molecular Immunology,Hou and coworkers provide novel insights into glucocorticoid(GC)treatment refractoriness in immune thrombocytopenia(ITP),reporting that myeloid-derived suppressor cells(MDSCs)contribute to GC resistance in ITP via impairments in their glucocorticoid receptor(GR)expression and mitochondrial metabolism[1].