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Impaired glucocorticoid receptor expression and mitochondrial metabolism in MDSCs contribute to glucocorticoid resistance in immune thrombocytopenia
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作者 Rick Kapur 《Cellular & Molecular Immunology》 SCIE CAS CSCD 2022年第7期858-860,共3页
In this issue of Cellular&Molecular Immunology,Hou and coworkers provide novel insights into glucocorticoid(GC)treatment refractoriness in immune thrombocytopenia(ITP),reporting that myeloid-derived suppressor cel... In this issue of Cellular&Molecular Immunology,Hou and coworkers provide novel insights into glucocorticoid(GC)treatment refractoriness in immune thrombocytopenia(ITP),reporting that myeloid-derived suppressor cells(MDSCs)contribute to GC resistance in ITP via impairments in their glucocorticoid receptor(GR)expression and mitochondrial metabolism[1]. 展开更多
关键词 METABOLISM GLUCOCORTICOID IMMUNOLOGY
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