Expression of NF-κ B and osteopontin of synovial fluid of patients with knee osteoarthritis

Objective:To explore the significance of osteopontin and nuclear factorκB(NF-κB) expression in patients with knee osteoarthritis.Methods:RT-PCR and enzyme-linked immunosorbent assay were used to measure the Osteopontin(OPN) and NF-κB concentration of knee joint synovial fluid of patients with knee osteoarthritis and trauma fractures,and analyze the relationship between the expressiones of them.Results:OPN and NF-κB expression at the mRNA and protein levels of patients with knee osteoarthritis were significantly higher than the control group, the result showed statistical significance(P【0.05).There was a positive correlation between the OPN levels in synovial fluid of patients with knee osteoarthritis and NF-κB expression levels (P【0.05).Conclusions:The high expression of OPN and NF-κB are closely related to occurrence and development of knee osteoarthritis.

Application Progress of Aromatherapy in Perioperative Patients

Aromatherapy is a sort of natural therapy for body maintenanceusing essential oils and vegetable oils extracted from natural plants. It belongsto the category of homeopathy. Aromatherapy combines the dual functions ofart and treatment, comprehensively considers the needs of human physiologyand psychology, and is widely used in the field of medical care. Aromatherapyis one of the complementary and alternative treatments extensively studiedat home and abroad. It has a relieving effect on postoperative pain, sleepdisturbance, nausea, vomiting and preoperative anxiety, and is an importantintervention in perioperative care. A large number of research data show thatfor a long time, the application of aromatherapy is an effective alternativeand auxiliary medical means, which can improve people’s comfort and solvemany health problems. There are a lot of controversies about the possiblerisks and safety of aromatherapy, but in general, compared with traditionaldrugs for the treatment of same diseases, aromatherapy is safe and has fewrecords of serious side effects. This review intends to provide an overview ofaromatherapy and its application status in the perioperative period, in orderto provide a reference for improving the comfort and quality of life of patientsin the perioperative period.