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Diagnostic accuracy of color Doppler in diagnosis of Hepatocellular carcinoma taking histopathology as gold standard
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作者 Wajid Ali Kanwal Saba +2 位作者 Nasir Raza Zaidi Tayyaba Majeed Mulazim Hussain Bukhari 《Journal of Biomedical Science and Engineering》 2013年第6期609-614,共6页
Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world and the third most common cause of cancer mortality. Despite the high numbers of patients diagnosed worldwide, HCC continues to pose challeng... Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world and the third most common cause of cancer mortality. Despite the high numbers of patients diagnosed worldwide, HCC continues to pose challenging clinical problems. Good-quality ultra sound with careful evaluation of the entire liver can be a screening examination for HCC in patients at risk. The aim of the study was to determine the diagnostic accuracy of the Doppler sonography for differentiation of hepatocellular carcinoma (HCC) from other focal liver lesions by taking histopathology as a gold standard. It was a cross-sectional survey, conducted in the Department of Diagnostic Radiology, King Edward Medical University/Mayo Hospital, Lahore in one year from 13-12-2010 to 12-12-2011. A total of 70 patients were included in this study with focal lesions on ultrasound are included while pregnant patients are excluded. After evaluating by Doppler sonography and doing core biopsy, the patients were sent to the Department of Pathology, Mayo Hospital for histopathological examination. Histopathology was assessed for confirmation of positive and negative cases. Mean age of the patients was 60.9 ± 4.7 years. Out of 70 patients, 47 patients (67.1%) were male while remaining 23 patients (32.9%) were female. On Doppler sonography 37 cases were positive for hepatocellular carcinoma and 33 cases were negative while 36 cases were positive and 34 negative on histopathology. On Doppler sonography, sensitivity (94.4%), specificity (91.1%), diagnostic accuracy (92.8%), positive predictive value (91.8%) and negative predictive value was 93.9%. We concluded that Doppler sonography is a useful method for differen- tiation of Hepatocellular carcinoma from other focal liver lesions, detection and characterization of hepatocellular carcinoma. 展开更多
关键词 HEPATOCELLULAR Carcinoma DOPPLER SONOGRAPHY FOCAL Liver LESIONS
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Complications of Peripartum Cardiomyopathy at the Departmental University Hospital Teaching of Borgou (Benin) in 2022: About 3 Cases
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作者 Léopold Houétondji Codjo Serge Hugues Mahougnon Dohou +11 位作者 Sèdjro Raoul Atade Fabrice Atika Hamondji Nicolas Amegan Chabi Olaniran Alphonse Biaou Kayivi Murielle Hounkponou Djidjoho Arnaud Sonou Mahouna Philippe Adjagba Marielle Dorine Soude Dominique Sacca Mèdéssè Rolande Quenum Aude Sourou Bodjrenou Martin Dèdonougbo Houenassi 《World Journal of Cardiovascular Diseases》 CAS 2022年第11期514-526,共13页
Introduction: Peripartum cardiomyopathy (PPCM) is a dilated cardiomyopathy occurring in the last month of pregnancy or the first five months postpartum without pre-existing cardiovascular pathology. It is a major caus... Introduction: Peripartum cardiomyopathy (PPCM) is a dilated cardiomyopathy occurring in the last month of pregnancy or the first five months postpartum without pre-existing cardiovascular pathology. It is a major cause of pregnancy-related heart failure with high morbidity and mortality. In severe forms (10% to 15% of cases), thrombo-embolic complications are the main cause. The initial hemodynamic evolution is totally unpredictable and sometimes extremely brutal and fatal. The objective of this work was to show the often pejorative evolution of PPCM in our country. Methods: We report in this work three serious clinical cases revealing the complications of this PPCM among patients admitted to the cardiology department of the CHUD-B/A in 2022 for heart failure. The data were collected according to the Declaration of Helsinki. Patients and Observations: The first case was a PPCM with severe left ventricular (LV) systolic dysfunction complicated by spontaneous left intraventricular contrast and right superficial sylvian ischemic stroke. The second case reports a global cardiac decompensation of a PPCM with severe LV systolic dysfunction complicated by an apical thrombus. The third case is that of a state of cardiogenic shock complicating a PPCM with severe LV systolic dysfunction. Among our 03 patients presenting these severe forms of PPCM, the evolution, in spite of the symptomatic and prognostic treatments of the heart failure, and even of the complications, was unfavourable with death in two of them. Conclusion: Complications of PPCM are frequent and fatal in Benin. 展开更多
关键词 CARDIOMYOPATHY PERIPARTUM COMPLICATIONS Parakou BENIN
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Maternal and Fetal Prognosis of Uterine Rupture in the Health District of Koutiala
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作者 Cheickna Sylla Soumana Oumar Traoré +7 位作者 Sitapha Dembele Seydou Z. Dao Mamadou Traoré Amadou Boucoum Seydou Fané Ibrahima Tegueté Youssouf Traoré Niani Mounkoro 《Open Journal of Obstetrics and Gynecology》 2020年第9期1187-1196,共10页
<strong>Introduction:</strong><span style="font-family:Verdana;"> Uterine rupture is a complete or incomplete non-surgical continuity solution of the wall of the gravid uterus. Indeed, it i... <strong>Introduction:</strong><span style="font-family:Verdana;"> Uterine rupture is a complete or incomplete non-surgical continuity solution of the wall of the gravid uterus. Indeed, it is a Affection obstetrical condition whose maternal-fetal prognosis is poor in terms of morbidity and mortality. </span><span style="font-family:Verdana;"><strong>Objectives:</strong></span><span style="font-family:Verdana;"> To assess the risk factors for uterine rupture in the Koutiala Health District. </span><span style="font-family:Verdana;"><strong>Methods:</strong></span><span style="font-family:Verdana;"> This was a descriptive and analytical cross-sectional prospective collection study from January 1, 2019 to December 31, 2019, a 12-month period. In our study, all patients admitted to the maternity ward were included during the study period for which the diagnosis of uterine rupture was made. </span><span style="font-family:Verdana;"><strong>Results:</strong></span><span style="font-family:Verdana;"> Out of a total of deliveries, we recorded 27 cases of uterine rupture, a frequency of 1.04%. The average age of our patients was 32 years with extremes of 19 and 45 years. We notice 92.6% of uterine ruptures during the transfer. Almost 3/4 of our parturients were out of school 70.4% versus 11.1% in primary school and 18.5% in secondary school. The majority of patients affected by uterine rupture came from rural areas 85.2%. Only 14.8% were from Koutiala city. The admission time to the Koutiala Reference Health Centre was 2 hours 30 minutes in 50.85% of our patients with extremes of 15 minutes and 4 hours 30</span><span style="font-family:" color:windowtext;font-weight:normal;"=""> </span><span style="font-family:Verdana;">min. The average parity was 6.30 - 3036;large </span><span style="font-family:Verdana;">multiparous</span><span style="font-family:Verdana;"> accounted for 63% in our sample followed by </span><span style="font-family:Verdana;">multiparous</span><span style="font-family:Verdana;"> 18.5%. As for pregnancy follow-up, 100% of the patients had not performed any prenatal consultations. In 85.2% hysterrhaphy was performed intervention and hysterectomy in 14.8%. Maternal prognosis was satisfactory in 96.30% of cases. From the point of view of morbidity: 1 case of bladder-vaginal fistula was recorded and corrected by the bladder survey at home for 15 days. Late complications were the occurrence of anemia in 16 patients who were transfused and 1 case of phlebitis. We recorded 1 maternal death and 25 stillbirths. </span><span style="font-family:Verdana;"><strong>Conclusion:</strong></span><span style="font-family:Verdana;"> Uterine rupture is one of the leading causes of maternal and fetal mortality in Mali.</span> 展开更多
关键词 Uterine Rupture Maternal and Fetal Prognosis
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Services provided at the premarital counseling center and characteristics of the clients, in kayseri, Turkey
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作者 Muruvvet Baser Tulay Ozkan +2 位作者 Pinar Tekinsoy Evrim Albayrak Sultan Tasci 《Health》 2011年第6期333-337,共5页
Objectives: The study was conducted retro-spectively to evaluate the services offered at the Premarital Counseling Center (PCC) and the characteristics of the individuals who obtained counseling at the center in Kayse... Objectives: The study was conducted retro-spectively to evaluate the services offered at the Premarital Counseling Center (PCC) and the characteristics of the individuals who obtained counseling at the center in Kayseri. Methods: A retrospective review is based on data from the Premarital Counseling Center (PCC) in Kayseri. Seven hundred fifty four (754) individuals who attended the Center were included in the study sample. Data were collected from the Center’s records. Records of all people were reviewed by the researchers. Differences in proportions were analyzed by Chi square test and t test. Results: The age-average of the individuals who consulted the PCC was 26.2 ± 8.3, 91.1% of the individuals had Rh (+), 99.5% of them had VDRL (-), 3.9% had Hbs Ag (+), 0.8% had HCV (+) while none of the individuals was HIV (+) affected. It’s shown that 90.6% of the individuals who were between the ages of 15 - 19 were women, 9.4% of them were men. The difference between the age and the gender of the individuals who came to the center was considered significant. It was determined that the individuals who received counseling services at the PCC were not given any kind of educational and consulting services before. 展开更多
关键词 MARRIAGE Premarital Counseling
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Ovarian Sex Cord-Stromal Tumors in Postmenopausal Women and Total Laparoscopical Management
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作者 Andrea Tinelli Marcello Pellegrino +1 位作者 Vincenzo Emanuele Chiuri Antonio Malvasi 《Journal of Cancer Therapy》 2010年第1期31-35,共5页
BACKGROUND: Ovarian sex-cord stromal tumors (SCST) take up 5% of the ovarian neoplasm and may develop in?to?an ovarian mass or a haemoperitoneum. The surgical management of SCST in early-stage adult patients is not we... BACKGROUND: Ovarian sex-cord stromal tumors (SCST) take up 5% of the ovarian neoplasm and may develop in?to?an ovarian mass or a haemoperitoneum. The surgical management of SCST in early-stage adult patients is not well?defined. CASE REPORT: A 69 year-old postmenopausal woman was admitted for metrorrhagia, a right ovary mass and?increasing pelvic pain. Preoperative clinical and instrumental examination suspected an ovarian tumor, and the?laparoscopic right ophorectomy and the frozen section suggested an ovarian SCST. To fast restore and preserve woman?integrity, total laparoscopic hysterectomy (TLH) plus left salpingo-ophorectomy (SO) were performed, without complications?in the short and long term follow-up. CONCLUSION: In the authors’ opinion, the minimally invasive management?of SCST by TLH plus bilateral SO followed by a prolonged surveillance and without intensive surgical staging,?could be an appropriate clinical and surgical choice in elder patient at early stage, since these tumors are slow at?growth, recurring locally and only a long time after initial treatment. We suggest, after a minimally invasive treatment,?a possible “wait and see” option, as in our case report. 展开更多
关键词 MENOPAUSE LAPAROSCOPY OVARIAN Cancer Sex Cord-Stromal OVARIAN TUMORS GRANULOSA Cell TUMORS MINIMALLY Invasive Treatment.
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The Free Cesarian in the Health District of Bougouni
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作者 Cheickna Sylla Soumana Oumar Traoré +7 位作者 Sitapha Dembele Seydou Z. Dao Lassana Togola Amadou Boucoum Seydou Fané Ibrahima Tegueté Youssouf Traoré Niani Mounkoro 《Open Journal of Obstetrics and Gynecology》 2020年第9期1233-1245,共13页
<strong>Purpose: </strong><span style="font-family:;" "=""><span style="font-family:Verdana;">The purpose of this study was to assess the impact of free caesa... <strong>Purpose: </strong><span style="font-family:;" "=""><span style="font-family:Verdana;">The purpose of this study was to assess the impact of free caesarean section on maternal-fetal prognosis. </span><b><span style="font-family:Verdana;">Materials and Methods:</span></b><span style="font-family:Verdana;"> This was a descriptive, cross-sectional, comparative analytical study of one year of non-free caesarean section and three years of free with retrospective data collection. Our study took place from January 1, 2004 to December 31, 2004 and from January 1, 2007 to December 31, 2009. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Caesarean section completion rates are 1.28%, 1.30%, 1.53%, 1.32% respectively in 2004, 2007, 2008, 2009. The average age was 27 years with extremes of 15 to 40 years. The peak of evacuations was recorded in 2007 with a rate of 89.4% and the peak of direct admissions in 2009 with a rate of 14.9%. An adequate means of transport was used in 77.20%. In 22.80% of cases an inadequate means was used. The indications of caesarean sections were dominated by preeclampsi</span></span><span style="font-family:Verdana;">a</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> 211/1045 caesarean section followed by acute fetal suffering 179/1045;86/1045;placenta previa 64/1045;presentations of the shoulder </span><i><span style="font-family:Verdana;">i.e.</span></i><span style="font-family:Verdana;"> 53/1045;pre-rupture syndrome 44/1045;retro-placental hematoma 27/1045. In terms of maternal prognosis: we noted maternal deaths with a rate of 2.4%</span></span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">2</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">4%</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">4</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">3%</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">0.4% respectively in 2004</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">2007</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">2008</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">2009. And stillbirth rates were 17.6%</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">22</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">4%</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">27</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">4%</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">21.7% respectively in 2004</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">2007</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">2008</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">2009</span><span style="font-family:Verdana;">. </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The average length of hospitalization was 10 days. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Free caesarean section would be a factor in improving the maternal-fetal prognosis.</span></span> 展开更多
关键词 Caesarean Section Free of Charge Frequency Indications PROGNOSIS
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COVID-19pneumonia in an Iraqi pregnant woman with preterm delivery
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作者 Hayder M.Al-kuraishy Thabat J.Al-Maiahy +2 位作者 Ali I.Al-Gareeb Rasha A.Musa Zaid H.Ali 《Asian pacific Journal of Reproduction》 2020年第3期156-158,共3页
Rationale:Coronavirus disease 2019(COVID-19)is a highly infectious disease due to the severe acute respiratory syndrome coronavirus type 2(SARS-CoV2).Vertical transmission and clinical presentation of COVID-19 in preg... Rationale:Coronavirus disease 2019(COVID-19)is a highly infectious disease due to the severe acute respiratory syndrome coronavirus type 2(SARS-CoV2).Vertical transmission and clinical presentation of COVID-19 in pregnancy is still obscure.Additionally,the potential hazard of COVID-19 in pregnancy on the fetus and post-delivery risk for the neonate remain under investigations.Patient concern:A young-aged Asian pregnant woman with 28 weeks of gestation presented with fever,dyspnoea,headache,and joint pain with decreased fetal movement for about one week.Diagnosis:The patient was diagnosed with COVID-19 pneumonia.Interventions:The patient was referred to the quarantine sector and was treated with chloroquine orally,intravenous fluid and other supportive treatment.Outcomes:After one week of treatment,the patient improved.Seventeen days after admission to hospital and at 30 weeks of gestation,she started vaginal preterm delivery of a viable healthy neonate with negative COVID-19 test for two occasions.Lessons:COVID-19 pneumonia during pregnancy presents with similar clinical presentation of non-pregnant women.COVID-19 pneumonia during pregnancy increases the risk of preterm labour without evidence of vertical transmission. 展开更多
关键词 CORONAVIRUS DISEASE 2019(COVID-19) PREGNANCY VERTICAL TRANSMISSION
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ZMYM3:a new candidate gene in nonobstructive azoospermia?
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作者 Morgane Le Beulze Nelly Swierkowski-Blanchardl +6 位作者 Farah Ghieh Joanne Fortemps Carole Gerault Valerie Scrazin Anne Louboutin-Sanchez Marc Bailly Francois Vialard 《Asian Journal of Andrology》 SCIE CAS CSCD 2023年第5期648-649,共2页
Dear Editor,Infertility affects about 15%of couples of childbearing age.i About half of these cases can be attributed predominantly to a male factor,such as a quantitative or qualitative impairment in spermatogenesis.... Dear Editor,Infertility affects about 15%of couples of childbearing age.i About half of these cases can be attributed predominantly to a male factor,such as a quantitative or qualitative impairment in spermatogenesis.The etiology of male infertility is related to anatomic,genetic,and environmental causes,being sometimes multifactorial and of unknown or idiopathic origins.At present,genetic screening for nonobstructive azoospermia(NOA)is generally limited to karyotyping for the identification of chromosome abnormalities such as 47,XXY,46,X,der(X)t(X;Y)(p22.3;p11.2),chromosome rearrangements,and Y chromosome microdeletions.Whole-genome analyses have shown that over 100 gene variants are associated with a male infertility phenotype,and the list continues to grow;hence,a large number of genes are involved in spermatogenesis.The continuing identification of genes responsible for male infertility in general and azoospermia,in particular,is a major challenge in both research and the diagnosis ofmale infertility. 展开更多
关键词 AZOOSPERMIA OBSTRUCTIVE DIAGNOSIS
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