China’s Experience in Controlling COVID-19

Background: In less than a year, COVID-19 has swept the world and continued, too, seriously threatening the safety of all mankind, and caused great social panic and global economic and financial crisis. At the beginning, the epidemic was first diagnosed in China and the epidemic was severe. Under the strong command of the highest level of the Chinese government, the whole Chinese people united as one, and achieved initial results in the struggle against COVID-19 with scientific prevention and control. Objective: Summarizing China’s experience and lessons in combating the epidemic is undoubtedly very beneficial to the people of the world in jointly combating the impact of the COVID-19 epidemic. Measures: The article shows the imminent Chinese experience in controlling the spread of SARS-CoV-2. It details the lines of action and the measures taken to control this epidemic in the country where the population is quite large. The most important experience is: strong organizational leadership, enhanced cooperation with the WHO, the establishment of a national anti-epidemic headquarters, responsible for the command and control of human, financial and material resources throughout the country, and local officials at all levels in the front line of the epidemic, Heart to heart with the people, breathing together and sharing a common destiny. Prevention is the first, prevention and treatment are combined. All measures were taken to control the source of infection, cut off the spread and protect susceptible people. Conclusion: As long as the people of the world unite, make scientific decisions and learn from the successful experience of countries around the world, especially the China’s experience, combine the national conditions of each country, and use the wisdom of all man-kind to deal with the common enemy SARS-CoV-2 and COVID-19, we can definitely win this people’s war against the disease.

Meta-Analysis of Polymerase Chain Reaction in the Detection of Human Leptospirosis

Leptospirosis,a major zoonotic disease widespread in the world,would infect humans and other animals by direct contacting with the soil or water contaminated by the pathogenic leptospires.This report analyzes the accuracy of polymerase chain reaction(PCR)assay used in the detection of leptospira specific genes in humans.Seventeen published articles which included 2526 samples satisfied all inclusion standards and were applied to meta-analysis.Pooled sensitivity and specificity were 0.73(95%CI 0.70-0.76)and 0.94(95%CI 0.93-0.95),respectively.Heterogeneity was statistically significant among studies,but none of the sources for heterogeneity(disease stage,PCR type,targeted genes)could adequately interpret this finding.Meta-regression advised that real-time PCR(qPCR)targeted 16 s rRNA would be the best choice for early detection of cases during the acute stage of the disease and was accounted as a good screening tool in all stages of the disease.