Objective：To study the survival and ability of inducing axonal regeneration of the Schwann cells after the peripheral nerve being grafted into spinal cord. Methods：A total of 30 adult female Wistar rats were randoml...Objective：To study the survival and ability of inducing axonal regeneration of the Schwann cells after the peripheral nerve being grafted into spinal cord. Methods：A total of 30 adult female Wistar rats were randomly divided into the VN （vascularized peripheral nerve） and PN （peripheral nerve） groups. A 5-mm spinal cord defect of the left posterior column was made at the T1-3 vertebral level. The defect was grafted with the vascularized or isolated peripheral nerve respectively. The survival and proliferation of the Schwann cells were assessed by histological and morphometric analysis 8 weeks after the operation. Resuits：In the VN group, the peripheral nerve grew into the cord with lots of Schwann cells survived and proliferated, and had more NF and S-100 positive fibers than in the PN group. Conclusion：The vascularized peripheral nerve enhances the survival and proliferation of the Schwann cells and prompts the regener- ation of injured axon of the central nerve system to certain degree.展开更多
To analyze retrospectively the surgical treatment of 21 cases of infected arterial injuries of the major limb hospitalized from 1989 to 2003 in our department. Methods： After a radical debridement and drainage, an a...To analyze retrospectively the surgical treatment of 21 cases of infected arterial injuries of the major limb hospitalized from 1989 to 2003 in our department. Methods： After a radical debridement and drainage, an autologous vessel bypass reconstruction, simple vessel ligation or amputation were carried out respectively according to each patient＇s condition. In order to make a better milieu for the grafts, local musculo-cutaneous flaps were translocated to cover the wounds in 9 cases. Results ： 1 case （ 4.8 % ） died during the treatment. 5 cases （ 5/21, 23.8 % ） underwent amputations. Blood supply reconstruction was successful in 15 cases （15/21, 71.4%）. 93.3% （14/15） of the cases were successful in getting an unobstructed vessel at early stage. Thrombosis occurred in 1 case （ 1/15, 6.7 % ） and a sound result was obtained after a second operation. Conclusions： Radical debridement combined with bypass vessel reconstruction with autologous vein and with musculo-cutaneous flap translocation is an effective treatment for infective limb vascular injuries.展开更多
文摘Objective：To study the survival and ability of inducing axonal regeneration of the Schwann cells after the peripheral nerve being grafted into spinal cord. Methods：A total of 30 adult female Wistar rats were randomly divided into the VN （vascularized peripheral nerve） and PN （peripheral nerve） groups. A 5-mm spinal cord defect of the left posterior column was made at the T1-3 vertebral level. The defect was grafted with the vascularized or isolated peripheral nerve respectively. The survival and proliferation of the Schwann cells were assessed by histological and morphometric analysis 8 weeks after the operation. Resuits：In the VN group, the peripheral nerve grew into the cord with lots of Schwann cells survived and proliferated, and had more NF and S-100 positive fibers than in the PN group. Conclusion：The vascularized peripheral nerve enhances the survival and proliferation of the Schwann cells and prompts the regener- ation of injured axon of the central nerve system to certain degree.
文摘To analyze retrospectively the surgical treatment of 21 cases of infected arterial injuries of the major limb hospitalized from 1989 to 2003 in our department. Methods： After a radical debridement and drainage, an autologous vessel bypass reconstruction, simple vessel ligation or amputation were carried out respectively according to each patient＇s condition. In order to make a better milieu for the grafts, local musculo-cutaneous flaps were translocated to cover the wounds in 9 cases. Results ： 1 case （ 4.8 % ） died during the treatment. 5 cases （ 5/21, 23.8 % ） underwent amputations. Blood supply reconstruction was successful in 15 cases （15/21, 71.4%）. 93.3% （14/15） of the cases were successful in getting an unobstructed vessel at early stage. Thrombosis occurred in 1 case （ 1/15, 6.7 % ） and a sound result was obtained after a second operation. Conclusions： Radical debridement combined with bypass vessel reconstruction with autologous vein and with musculo-cutaneous flap translocation is an effective treatment for infective limb vascular injuries.
