Aspirin-exacerbated respiratory disease(AERD)patients with CRSwNP suffer from reduced quality of life,reduced economic productivity,and higher risk of depression and sleep dysfunction.These patients often require freq...Aspirin-exacerbated respiratory disease(AERD)patients with CRSwNP suffer from reduced quality of life,reduced economic productivity,and higher risk of depression and sleep dysfunction.These patients often require frequent medical and surgical therapy,including functional endoscopic sinus surgery for recalcitrant disease.Given this severity,anti-type 2 biologic treatments are being investigated for use in this subgroup of patients with CRSwNP,including Omalizumab and Dupilumab.Preliminary data suggests that SNOT-22 related quality of life improvements following treatment with biologies are comparable to the current standard of care in the short term,but there is a lack of long-term data and standardized regimen that makes direct comparison difficult.Biologic therapies additionally require continuous use to avoid recurrence,and currently cost many times more than existing medical or surgical therapies.展开更多
Hypothesis:Three-dimensional(3D)printed temporal bones are comparable to cadaveric temporal bones as a training tool for otologic surgery.Background:Cadaveric temporal bone dissection is an integral part of otology su...Hypothesis:Three-dimensional(3D)printed temporal bones are comparable to cadaveric temporal bones as a training tool for otologic surgery.Background:Cadaveric temporal bone dissection is an integral part of otology surgical training.Unfortunately,availability of cadaveric temporal bones is becoming much more limited and concern regarding chemical and biological risks persist.In this study,we examine the validity of 3D-printed temporal bone model as an alternative training tool for otologic surgery.Methods:Seventeen otolaryngology trainees participated in the study.They were asked to complete a series of otologic procedures using 3D-printed temporal bones.A semi-structured questionnaire was used to evaluate their dissection experience on the 3D-printed temporal bones.Results:Participants found that the 3D-printed temporal bones were anatomically realistic compared to cadaveric temporal bones.They found that the 3D-printed temporal bones were useful as a surgical training tool in general and also for specific otologic procedures.Overall,participants were enthusiastic about incorporation of 3D-printed temporal bones in temporal bone dissection training courses and would recommend them to other trainees.Conclusion:3D-printed temporal bone model is a viable alternative to human cadaveric temporal bones as a teaching tool for otologic surgery.展开更多
Review articles can be extremely valuable.They synthesize information for readers,often provide clarity and valuable insights into a topic;and good review articles tend to be cited frequently.Review articles do not re...Review articles can be extremely valuable.They synthesize information for readers,often provide clarity and valuable insights into a topic;and good review articles tend to be cited frequently.Review articles do not require Institutional Review Board(IRB)approval if the data reviewed are public(including private and government databases)and if the articles reviewed have received IRB approval previously.展开更多
文摘Aspirin-exacerbated respiratory disease(AERD)patients with CRSwNP suffer from reduced quality of life,reduced economic productivity,and higher risk of depression and sleep dysfunction.These patients often require frequent medical and surgical therapy,including functional endoscopic sinus surgery for recalcitrant disease.Given this severity,anti-type 2 biologic treatments are being investigated for use in this subgroup of patients with CRSwNP,including Omalizumab and Dupilumab.Preliminary data suggests that SNOT-22 related quality of life improvements following treatment with biologies are comparable to the current standard of care in the short term,but there is a lack of long-term data and standardized regimen that makes direct comparison difficult.Biologic therapies additionally require continuous use to avoid recurrence,and currently cost many times more than existing medical or surgical therapies.
文摘Hypothesis:Three-dimensional(3D)printed temporal bones are comparable to cadaveric temporal bones as a training tool for otologic surgery.Background:Cadaveric temporal bone dissection is an integral part of otology surgical training.Unfortunately,availability of cadaveric temporal bones is becoming much more limited and concern regarding chemical and biological risks persist.In this study,we examine the validity of 3D-printed temporal bone model as an alternative training tool for otologic surgery.Methods:Seventeen otolaryngology trainees participated in the study.They were asked to complete a series of otologic procedures using 3D-printed temporal bones.A semi-structured questionnaire was used to evaluate their dissection experience on the 3D-printed temporal bones.Results:Participants found that the 3D-printed temporal bones were anatomically realistic compared to cadaveric temporal bones.They found that the 3D-printed temporal bones were useful as a surgical training tool in general and also for specific otologic procedures.Overall,participants were enthusiastic about incorporation of 3D-printed temporal bones in temporal bone dissection training courses and would recommend them to other trainees.Conclusion:3D-printed temporal bone model is a viable alternative to human cadaveric temporal bones as a teaching tool for otologic surgery.
文摘Review articles can be extremely valuable.They synthesize information for readers,often provide clarity and valuable insights into a topic;and good review articles tend to be cited frequently.Review articles do not require Institutional Review Board(IRB)approval if the data reviewed are public(including private and government databases)and if the articles reviewed have received IRB approval previously.
