Benefit of stem cells and skeletal myoblast cells in dilated cardiomyopathies

Although some authors suggest that there is mitotic division in the heart,most cardiomyocytes do not have the capacity to regenerate after myocardial infarction and when this occurs there is a deterioration of contractile function,and if the area of infarction is extensive ventricular remodeling may occur,leading to the development of heart failure.Cell transplantation into the myocardium with the goal of recovery of cardiac function has been extensively studied in recent years. The effects of cell therapy are based directly on the cell type used and the type of cardiac pathology.For myocardial ischemia in the hibernating myocardium, bone marrow cells have functional benefits,however these results in transmural fibrosis are not evident. In these cases there is a benefit of implantation with skeletal myoblasts,for treating the underlying cause of disease,the loss of cell contractility.

Wound healing activity of Delonix elata stem bark extract and its isolated constituent quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside in rats

Delonix elata L.is a Ceasalpinaceae species and is traditionally used in India for treatment of skin diseases,liver diseases and rheumatic problems.However,systematic evaluation of its wound healing activity is lacking.Thus,in the present study,we aimed to assess the wound healing activity of D.elata stem bark extract(DSE) and its isolated constituent quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside(QRPG) in rats.The formulations effects on wound healing were assessed by the wound contraction rate,epithelialization period,tensile strength,content of the hydroxyproline,hexosamine and uronic acid in granulation tissue,histopathological studies and Col 1 α(I) expression level in wound tissue by reverse transcription polymerase chain reaction(RT-PCR) study.The topical application of DSE ointment caused faster epithelialization,significant wound contraction(100%),and better tensile strength(710.5 ± 10.5 g/cm^2),while QRPG showed wound epithelialization with 98.2%contraction,better than that of the control group(78.18%).The biochemical analysis of granulation tissue revealed that DSE and QRPG significantly increased hydroxyproline,hexosamine and uronic acid content.A significant increase in the expression of Col 1 α(I) was observed in the wound tissue of DSE and QRPG treated rats.DSE and QRPG were shown to enhance wound healing by increasing collagen synthesis through upregulation of Col 1 α(I),thus validating ethnomedicinal uses.

Ethnomedicinal plants used in the treatment of skin diseases in Hyderabad Karnataka region,Karnataka,India

Objective:To document traditional medicinal plants knowledge used in treating skin diseases at Hyderabad Karnataka Region.Methods:The information on the use of medicinal plants in the treatment of skin diseases was gathered from traditional herbal healers and other villagers through interviews.Results:A total of 60 plants species belonging to 57 genera and 34 families were found useful and herewith described them along with the method of drug preparation,mode of administration,probable dosage and duration of treatment.Several new findings on the traditional rural practices were reported.Conclusions:The present study revealed that the Hyderabad Kamataka rural people is primarily dependent on medicinal plants for treating skin diseases.

Repercussion of Hall effect and nonlinear radiation on Couette-Poiseuille flow of Casson-Williamson fluid through upright microchannel

The main aim of the present work is to investigate the flow and heat transport properties of non-Newtonian Casson-Williamson fluid through an upright microchannel along with entropy generation analysis,and explore the effects of convective boundary conditions,Couette-Poiseuille flow,and nonlinear radiation.The movement of liquid is scrutinized with the Hall effect and exponential heat source.The rheological characteristics of the Casson-Williamson fluid model are also considered.By considering the desirable similarity variables,the equations of motion are reduced to nonlinear ordinary differential equations.The Runge-Kutta-Fehlberg fourth-fifth order method along with the shooting method is adopted to solve these dimensionless expressions.The detailed investigation is pictorially displayed to show the influence of effective parameters on the entropy generation and the Bejan number.One of the major tasks of the exploration is to compare the Casson fluid and the Williamson fluid.The results show that the rate of heat transfer in the Casson fluid is more remarkable than that in the Williamson fluid.

Luminescence and ESR Studies of CaS：Dy Phosphor

与 Dy 离子激活的 CaS 黄磷被准备由固态散开方法。黄磷被 X 光粉末衍射， thermogravimetric 和光致发光描绘。在 CaS 形成的缺点中心: Dy 用电子纺纱的技术被学习回声。在约 117 度 C 和 345 度 C.Irradiated CaS 的热照明发光曲线表演山峰: Dy 展览 ESR 由于缺点中心排队。缺点中心之一的热退火行为看起来在 117 度 C 和 345 度 C.This 中心与 TL 山峰相关被 2.0035 的各向同性的 g 值描绘并且被分到一个 F+- 中心。

Species diversity of birds in mangroves of Kundapura, Udupi District, Karnataka, Southwest Coast of India

We quantified species diversity of birds in mangroves at Kundapura from April-2010 to March-2013. We recorded 79 species of 36 families and 14 orders. Of these 71% are resident species, 22% are residential migrants and 8% are migratory. One endangered species, three near threatened species, and a few occasional visitors were re-corded. Species diversity and abundance of birds were greater during from October through May as there was availability of food, increased vegetation and the arrival of migratory birds. Minimum diversity was recorded from June through September owing to heavy rains, increased flow of water, limited availability of food and return of migratory birds.

Incidence of Urinary Tract Infections and Its Aetiological Agents among Pregnant Women in Karnataka Region

Urinary tract infection (UTI) is the most common medical complications of pregnancy together with anaemia and hypertension and it occurs approximately in 5%-10% of all pregnancies. The aim of this study was to determine the incidence of UTI and prevalence of uropathogens among pregnant women. During the study period from December 2009 to August 2010, 417 urine samples were analyzed. UTI was diagnosed by growth of at least 105 CFU/ml of a urinary tract pathogen in a culture of a midstream urine sample. The isolated bacteria were identified by biochemical tests. The results showed that 49.4% of pregnant women have UTI. E. coli which was the most frequently isolated organism (56.79%), followed by Klebsiella sps (19.9%), Pseudomonas sps (6.3%), and Proteus sps (5.8%). Other pathogens isolated were Enterobacter (3.8%), Citrobacter (1.4%) and Enterococcus sps (0.9%). Of the variables examined, the highest prevalence rate was observed where, 53.3% of the infected women were in the age group 36 to 40 years, 54.15% were in their 3rd trimester;also the highest infection rate (70.2%) was observed in 7th month of pregnancy, concluding that old age pregnancy increased parity prone for UTI apart from individual hygiene and economical status.

An Efficient Three-Party Authenticated Key Exchange Procedure Using Chebyshev Chaotic Maps with Client Anonymity

Internet of Things(IoT)applications can be found in various industry areas,including critical infrastructure and healthcare,and IoT is one of several technological developments.As a result,tens of billions or possibly hundreds of billions of devices will be linked together.These smart devices will be able to gather data,process it,and even come to decisions on their own.Security is the most essential thing in these situations.In IoT infrastructure,authenticated key exchange systems are crucial for preserving client and data privacy and guaranteeing the security of data-in-transit(e.g.,via client identification and provision of secure communication).It is still challenging to create secure,authenticated key exchange techniques.The majority of the early authenticated key agreement procedure depended on computationally expensive and resource-intensive pairing,hashing,or modular exponentiation processes.The focus of this paper is to propose an efficient three-party authenticated key exchange procedure(AKEP)using Chebyshev chaotic maps with client anonymity that solves all the problems mentioned above.The proposed three-party AKEP is protected from several attacks.The proposed three-party AKEP can be used in practice for mobile communications and pervasive computing applications,according to statistical experiments and low processing costs.To protect client identification when transferring data over an insecure public network,our three-party AKEP may also offer client anonymity.Finally,the presented procedure offers better security features than the procedures currently available in the literature.

DYNAMIC PRODUCTION PREDICTION AND PARAMETER IDENTIFICATION FOR GAS WELL WITH VERTICAL FRACTURE

In order to devoid the hard work and factitious error in selecting charts while analyzing and interpreting hydraulic fracturing fracture parameters, on the basis of the non-Darcy flow factor, this paper put out the non-Darcy flow mathematical model of real gas in the formation and fracture, established the production history automatic matching model to identify fracture parameters, and offered the numerical solutions of those models, which took the variation of fracture conductivity in production process. These results offered a precise and reliable method to understand formation, analyze and evaluate the fracturing treatment quality of gas well.

3-D FRACTURE PROPAGATION SIMULATION AND PRODUCTION PREDICTION IN COALBED

In accordance with the fracturing and producing mechanism in coalbed methane well, and combining the knowledge of fluid mechanics, linear elastic fracture mechanics, thermal transfer, computing mathematics and software engineering, the three-dimensional hydraulic fracture propagating and dynamical production predicting models for coalbed methane well is put forward. The fracture propagation model takes the variation of rock mechanical properties and in-situ stress distribution into consideration. The dynamic performance prediction model takes the gas production mechanism into consideration. With these models, a three-dimensional hydraulic fracturing optimum design software for coalbed methane well is developed, and its practicality and reliability have been proved by ex-ample computation.

SBOOSP for Massive Devices in 5G WSNs Using Conformable Chaotic Maps

The commercialization of the fifth-generation(5G)wireless network has begun.Massive devices are being integrated into 5G-enabled wireless sensor networks(5GWSNs)to deliver a variety of valuable services to network users.However,there are rising fears that 5GWSNs will expose sensitive user data to new security vulnerabilities.For secure end-to-end communication,key agreement and user authentication have been proposed.However,when billions of massive devices are networked to collect and analyze complex user data,more stringent security approaches are required.Data integrity,nonrepudiation,and authentication necessitate special-purpose subtree-based signature mechanisms that are pretty difficult to create in practice.To address this issue,this work provides an efficient,provably secure,lightweight subtreebased online/offline signature procedure(SBOOSP)and its aggregation(Agg-SBOOSP)for massive devices in 5G WSNs using conformable chaotic maps.The SBOOSP enables multi-time offline storage access while reducing processing time.As a result,the signer can utilize the pre-stored offline information in polynomial time.This feature distinguishes our presented SBOOSP from previous online/offline-signing procedures that only allow for one signature.Furthermore,the new procedure supports a secret key during the pre-registration process,but no secret key is necessary during the offline stage.The suggested SBOOSP is secure in the logic of unforgeability on the chosen message attack in the random oracle.Additionally,SBOOSP and Agg-SBOOSP had the lowest computing costs compared to other contending schemes.Overall,the suggested SBOOSP outperforms several preliminary security schemes in terms of performance and computational overhead.

An Efficient Three-Factor Authenticated Key Agreement Technique Using FCM Under HC-IoT Architectures

The Human-Centered Internet of Things(HC-IoT)is fast becoming a hotbed of security and privacy concerns.Two users can establish a common session key through a trusted server over an open communication channel using a three-party authenticated key agreement.Most of the early authenticated key agreement systems relied on pairing,hashing,or modular exponentiation processes that are computationally intensive and cost-prohibitive.In order to address this problem,this paper offers a new three-party authenticated key agreement technique based on fractional chaotic maps.The new scheme uses fractional chaotic maps and supports the dynamic sensing of HC-IoT devices in the network architecture without a password table.The projected security scheme utilized a hash function,which works well for the resource-limited HC-IoT architectures.Test results show that our new technique is resistant to password guessing attacks since it does not use a password.Furthermore,our approach provides users with comprehensive privacy protection,ensuring that a user forgery attack causes no harm.Finally,our new technique offers better security features than the techniques currently available in the literature.

Feelings and Senses Given to the Music Present at the Hospital during Hemodynamic Procedures: Cardiac Catheterization and Coronary Angioplasty

Several studies indicate that music has soothing effects and is beneficial in reducing stress and anxiety in coronary patients. It is known that reactions to music are considered to be subjective, however, results of previous studies suggest that variables such as changes in heart rate, in cerebral blood flow and heart rate variability increase with a faster musical tempo, regardless of individual preferences. The effects of stress on the cardiovascular system have also been proven. However, the meanings assigned to music when used during hemodynamic procedures are unknown, as are the meanings of the experience of these procedures. The aim of this research is to understand the senses and feelings of music for patients undergoing hemodynamic procedures, identify and interpret the related fantasies and emotions and study the possibility of deploying in hospitals the “Musical Method for Hemodynamic Procedures”, being developed by the author. This research is based on a Clinical-Qualitative Methodology. The sampling method is the theoretical saturation. The semi structured interview was used in order to obtain data that were submitted to content analysis. The subjects are patients undergoing hemodynamic procedures in the Hospital SEMPER (Permanent Medical Service), Belo Horizonte, Brazil. We conclude that within the experience of listening to music while undergoing catheterization, 100% of the patients interviewed claimed they had overcome the experience of stress and felt calm, tranquility, peace and happiness. Some patients described the music as a companion, as something that diverts their attention from fear, transporting them to an imaginary place, to another dimension. The episodic memory, the capacity to recognize a musical excerpt for which the spatiotemporal context surrounding its former encounter could be recalled, was also important, with surprising results, in the case of patients who underwent catheterization in the presence of music and, later, angioplasty without the presence of music.

Short Circuit Thermally Stimulated Discharge Current Measurement on PMMA:PEMA:PVDF Ternary Blends

The attainment of a better understanding and improvement of electrical properties of ternary blend is a task of particular scientific and economic importance. Ternary films of Poly (methylmethacrylate), Poly (ethlymathacrylate) and poly (vinlylidenefluoride) were prepared using solution cast technique. Thereafter, to study the hetro charges, homo-charges and interfacial charge formation in ternary system, the short circuit thermally stimulated discharge current (SC-TSDC) measurements were carried out on bilaterally metallized electrets. The ternary blend samples taken for the present investigations are hetrogeneous system involving three polymers differing in their conduction behaviour and dielectric property. Thus, unequal ohmic conduction currents arriving at the interface are expected to result in accumulation of charges at the interface or the Maxwell-Wagner effect. Clearly the Maxwell Wagner effect is expected to contribute discernibly to the observed TSDC’s of the ternary blends. The PMMA: PEMA: PVDF:: 100:100:50 blend exhibits highest tendency while 100:50:100 the least, towards the anomalous current flow. Moreover, the conductivity of 100: 100: 50 is found to be more and, therefore, a large amount of homocharge is injected leading to anomalous current.

Effect of confined one-gluon-exchange potential and instanton-induced interaction on nucleon–nucleon interaction

The effect of confined one-gluon-exchange potential and instanton-induced interaction potential in the singlet(1S0)and triplet(3S1)channels for nucleon–nucleon interaction has been investigated in the framework of the relativistic harmonic model using the resonating group method in the adiabatic limit with the Born–Oppenheimer approximation.The contributions of the different components of the interaction potentials have been analyzed.

One Pot Synthesis of Medicinally Important cis-2.Methyl-4-am i no s u bstituted-1,2,3,4-tetrahyd roq u i nolines

A simple synthesis of medicinally important cis-2-methyl-4-azapan-2-one-1,2,3,4-tetrahydroquinolines/cis-9- （2-methyl-l,2,3,4-tetrahydroquinolin-4-yl）-9H-carbazole was reported. Multicomponent one pot synthesis with ani- lines and N-vinylcaprolactam/N-vinyl carbazole via imino Diels-Alder reaction by using antimony trichloride as catalyst and acetonitrile as solvent was employed. NMR technique （2D） was used to study the regio- and stereo- chemistry of newly synthesized compounds. The cis diastereo-selectivity of the products was predicted by COSY and NOESY studies.

Aged diabetic amputee with COVID-19:A medication therapy

To the editor:Both innate and acquired immunity can be presented in the human body.Immunity defends us against disease of foreign organisms like bacteria,viruses,and other microbes.'Corona virus disease 2019(COVID-19)has been declared a global pandemic by the World Health Organization,as the novel coronavirus continues to spread swiftly over the world.