Existence and exponential stability of almost-periodic solutions for MAM neural network with distributed delays on time scales

This paper is concerned with multidirectional associative memory neural network with distributed delays on almost-periodic time scales.Some sufficient conditions on the existence,uniqueness and the global exponential stability of almost-periodic solutions are established.An example is presented to illustrate the feasibility and effectiveness of the obtained results.

Approximate Solution of Fuzzy Matrix Equations with LR Fuzzy Numbers

In the paper, a class of fuzzy matrix equations AX=B where A is an m × n crisp matrix and is an m × p arbitrary LR fuzzy numbers matrix, is investigated. We convert the fuzzy matrix equation into two crisp matrix equations. Then the fuzzy approximate solution of the fuzzy matrix equation is obtained by solving two crisp matrix equations. The existence condition of the strong LR fuzzy solution to the fuzzy matrix equation is also discussed. Some examples are given to illustrate the proposed method. Our results enrich the fuzzy linear systems theory.

The History Journey of A Literary Slogan——Reality

As a literary slogan given to a special meaning by history, ‘reality＇ has constituted a dominant clue in the evolution of the ideological trend of realism in 20th Century Chinese Literature. In the ‘New Literature Movement＇ of May 4th Movement,‘reality＇, as the characterization of scientific rationality spirit and an imposition on the description of the objective reality, has been incorporated into the perspective of Modern Chinese literature： In the 1950s and 1960s, it protested to obtain an independent literary discourse as a saving weapon; in the early 1980s, it‘restored＇ realism as a theory starting point of ‘re-enlightenment＇. In the late 1980s, with the conversion of historical context, and the subversion and reconstruction of Western ‘refer to＇ concept to ＂reality＂ concept of traditional epistemology, ‘reality＇ ended its historic mission, and thus to retire

4,4'-二(苯并咪唑-1-甲基)联苯和间苯二甲酸构筑的钴、镍配合物的合成及性质研究（英文）

目的:研究苯并咪唑类化合物结构与性质之间的关系,探讨具有抗菌性质新型苯并咪唑类配合物材料的合成方法。方法:溶剂热条件下,硝酸钴、硝酸镍与4,4'-二(苯并咪唑-1-甲基)联苯(bbmb)和间苯二甲酸(IPA)的自组装生成2个新型配合物{[Co(bbmb)(IPA)]·(H_2O)_3}_n(1)和{[Ni(bbmb)(IPA)(H_2O)]·H_2O}_n(2),并对配合物进行X-射线单晶衍射、热重分析、X-射线粉末衍射及固体紫外等表征。结果:配合物1属于单斜晶系,具有含S形链的二维层状结构,配合物2属于三斜晶系,具有含之字形链和直链的二维层状结构,且2种配合物都具有很强的固体紫外吸收。结论:由具有抗菌性的苯并咪唑衍生物与不同金属离子通过自组装合成了具有不同结构的2种新型配合物,为新型抗菌性配合物的设计合成提供了参考。

Effect of Bushenwenyanghuayu decoction on nerve growth factor and bradykinin/bradykinin B_1 receptor in a endometriosis dysmenorrhea mouse model

OBJECTIVE:To observe the effects of Bushenwenyanghuayu decoction(BD),a Traditional Chinese Medicine(TCM),on the serum concentration of nerve growth factor(NGF) and bradykinin(BK),and protein and mRNA levels of NGF and bradykinin B_1receptor(BKB1R) in a mouse model of endometriosis dysmenorrhea.METHODS:Seventy-five experimental female BALB/c mice were randomly divided into five groups,15 mice each:sham,model,BD high dose(61.67 g/kg),BD low dose(15.42 g/kg),and gestrinone(0.4 mg/kg) groups.All the mice except for those in the sham group underwent auto-transplantation surgery and were gavaged estradiol valerate(0.5 mg/kg,daily for 12 days) after surgery.On the 12 th day,1 h after administration,writhing response was induced by intraperitoneal injection of oxytocin at 2 U/mouse.The writhing frequency and latency were recorded and the volume of the ectopic foci was measured.The concentration of serum NGF and BK was detected by enzyme-linked immunosorbent assay,the protein expression of NGF and BKB1 R was tested by immunohistochemistry and western blotting,and NGF and BKB1 R mRNAs were detected by real-time PCR.RESULTS:Compared with the model group,the volume of the ectopic foci in the treatment groups was significantly lower(P < 0.01),the writhing frequency was decreased(P < 0.05),and the writhing latency was prolonged(P < 0.01).Compared with the sham group,serum NGF and BK levels in the model group were significantly increased(P <0.01).There were positive correlations for writhing frequency among the NGF and BK groups(P <0.01).The serum NGF and BK levels were significantly lower in the treatment groups than the model group(P < 0.05).The protein expression of NGF,BKB1 R was significantly decreased in the treatment groups compared with the model group(P < 0.01).NGF and BKB1 R mRNA expression was significantly decreased in the treatment groups compared with the model group(P < 0.01).CONCLUSION:NGF and BK/BKB1 R may play an important role in the development of endometriosis-associated dysmenorrhea,and BD was found to inhibit the development of endometriosis and relieve dysmenorrhea by influencing NGF and BK/BKB1 R mRNA and protein levels.

Unexpected carbon-oxygen bond cleavage of THF promoted by guanidinate titanium complex/lithium diisopropylamide: Synthesis and crystal structure

An unexpected carbon-oxygen bond cleavage of THF (THF = tetrahydrofuran) promoted by guanidinate titanium complex was described. Guanidinate lithium [Pr2iNC(NCy)2]Li (Cy = cyclohexyl) formed in situ reacted with TiCl4(THF)2 in a 2:1 molar ratio to produce the gua- nidinate titanium chloride [Pr2iNC(NCy)2]2TiCl2 (1) in good yield. The reaction of [Pr2iNC(NCy)2]2TiCl2 with lithium diisopropylamide in THF afforded an unexpected [Pr2iNC(NCy)2]2Ti(OBun)2 (2), which was formed by the cleavage of carbon-oxygen bond of THF. Complexes 1 and 2 were fully characterized by elemental analysis, NMR and IR spectroscopies, and X-ray crystal structure determination for complex 2.

“Block and attack”strategy for tumor therapy through ZnO_(2)/siRNA/NIR-mediating Zn^(2+)-overload and amplified oxidative stress

Intracellular zinc ion(Zn^(2+))accumulation disrupts the Zn^(2+)homeostasis,providing an ion-overloading anticancer strategy with great potential.The self-adaptation of tumor cells to ion concentration,however,puts forward higher requirements for the design of ion-overloading strategy.Herein,“block and attack”antitumor strategy was applied through a composite nanomaterials(UHSsPZH NPs).The strategy demonstrated powerful ion interference ability through both“blocking”the efflux of excess Zn^(2+)via gene silencing and“attacking”tumor cells via target delivery of ZnO_(2).After cellular internalization,ZnO_(2) was degraded to Zn^(2+)and hydrogen peroxide(H_(2)O_(2)),and the gene expression of zinc transporter 1(ZnT1)was silenced by targeting of released siRNA,which together caused intracellular Zn2+-overload.Disorder of Zn^(2+)further interfered with intracellular Ca^(2+)homeostasis,inhibited the electron transport chain and promoted the production of endogenous reactive oxygen species(ROS),which assisted the“attack”to tumor cells together with the exogenous ROS generated by UHSsPZH NPs under 980 nm laser irradiation.In summary,this work supplies a“block and attack”strategy for the application of ion homeostasis interference in tumor therapy.

Balanced Truncation Based on Generalized Multiscale Finite Element Method for the Parameter-Dependent Elliptic Problem

In this paper,we combine the generalized multiscale finite element method(GMsFEM)with the balanced truncation(BT)method to address a parameterdependent elliptic problem.Basically,in progress of a model reduction we try to obtain accurate solutions with less computational resources.It is realized via a spectral decomposition from the dominant eigenvalues,that is used for an enrichment of multiscale basis functions in the GMsFEM.The multiscale bases computations are localized to specified coarse neighborhoods,and follow an offline-online process in which eigenvalue problems are used to capture the underlying system behaviors.In the BT on reduced scales,we present a local-global strategy where it requires the observability and controllability of solutions to a set of Lyapunov equations.As the Lyapunov equations need expensive computations,the efficiency of our combined approach is shown to be readily flexible with respect to the online space and an reduced dimension.Numerical experiments are provided to validate the robustness of our approach for the parameter-dependent elliptic model.