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Recurrent ectopic pancreatitis of the jejunum and mesentery over a 30-year period 被引量:4
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作者 John CT Wong Charlotte Robinson +5 位作者 Edward C Jones Alison Harris Charles Zwirewich Robert Wakefield Richard K Simons Eric M Yoshida 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2011年第2期218-220,共3页
BACKGROUND:Ectopic pancreas is defined as pancreatic tissue found outside its usual anatomical position,with no ductal or vascular communication with the native pancreas. We describe a case of ectopic pancreas of the ... BACKGROUND:Ectopic pancreas is defined as pancreatic tissue found outside its usual anatomical position,with no ductal or vascular communication with the native pancreas. We describe a case of ectopic pancreas of the small bowel and mesentery causing recurrent episodes of pancreatitis, initially suspected on computed tomography(CT)and magnetic resonance cholangiopancreatography(MRCP),and confirmed on histological review of the resection. METHODS:A 67-year-old woman presented with clinical symptoms and biochemical evidence of pancreatitis.She had similar episodes over the past 30 years with unrevealing investigations,and was concluded to have idiopathic pancreatitis. She underwent CT and MRCP,with findings suggestive of ectopic pancreas,a diagnosis confirmed on histology of the resection. RESULTS:MRCP identified a mass in the proximal small bowel mesentery isointense to the native pancreas,with a small duct draining into a proximal jejunal loop.The resected specimen consisted of normal parenchyma with lobulated acinar tissue with scattered islets of Langerhans,an occasional ductular structure,and admixed areas of adipose tissue.The patient remained asymptomatic with normal biochemistry six months post-operatively. CONCLUSION:In an individual with abdominal pain,elevated serum amylase/lipase,but imaging findings of a normal native pancreas,ectopic pancreatitis should be considered,and can be evaluated by CT and MRCP. 展开更多
关键词 ectopic pancreas gastrointestinal tract endoscopic ultrasound computed tomography magnetic resonance cholangiopancreatography
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中国人和日本人胰腺癌组织中pBcl-2和pBax表达的比较
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作者 周建平 董明 +3 位作者 Nio Yoshinori 孔凡民 郑新宇 郭克建 《中国医学科学院学报》 CAS CSCD 北大核心 2005年第5期611-614,共4页
目的比较中国和日本人胰腺浸润性导管癌中pBcl-2和pBax的表达情况,研究二者与胰腺癌患者预后之间的关系。方法采用免疫组织化学方法,检测59例中国和65例日本胰腺浸润性导管癌患者癌组织中pBcl-2和pBax的表达情况,并进行比较。结果在59... 目的比较中国和日本人胰腺浸润性导管癌中pBcl-2和pBax的表达情况,研究二者与胰腺癌患者预后之间的关系。方法采用免疫组织化学方法,检测59例中国和65例日本胰腺浸润性导管癌患者癌组织中pBcl-2和pBax的表达情况,并进行比较。结果在59例中国患者中,pBcl-2和pBax的阳性表达率分别为35.6%和49.2%;在65例日本患者中,二者的阳性表达率分别为23.1%和64.7%。在男性患者和组织学中分化的患者中,pBcl-2的表达中日间差异有显著性(χ2=4.447,P=0.035;χ2=4.114,P=0.043);在65岁以上人群中,pBax的表达中日间差异也有显著性(χ2=6.657,P=0.010)。中日pBcl-2(+)组患者的术后中位生存时间与pBcl-2(-)组相比差异有显著性(χ2=9.99,P=0.0016;χ2=7.63,P=0.0058);日本pBax(+)组患者的术后中位生存时间与pBax(-)组相比差异有显著性(χ2=9.37,P=0.0022);中日pBcl-2(+)组之间及pBax(+)组之间术后生存时间相比差异均有显著性(χ2=4.48,P=0.0342;χ2=5.23,P=0.023)。结论pBcl-2和pBax在中日胰腺癌患者中均有较高的表达。在中日两国患者中,pBcl-2表达均提示较好的预后。pBax表达在日本患者中可提示较好的预后,而在中国患者中却没有显著意义。 展开更多
关键词 胰腺癌 pBel-2 pBax 免疫组织化学
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