Acupuncture can intervene with and treat vascular dementia(VD)through multiple targets and pathways.The mechanisms of its action involve inhibiting central inflammatory responses,regulating neuronal synaptic plasticit...Acupuncture can intervene with and treat vascular dementia(VD)through multiple targets and pathways.The mechanisms of its action involve inhibiting central inflammatory responses,regulating neuronal synaptic plasticity,modulating oxidative stress,reducing neuronal apoptosis,and adjusting cellular autophagy.This paper summarizes researches on the mechanisms of acupuncture treatment for vD over the past decade,aiming to provide theoretical support for the clinical application of acupuncture in treating VD and offer a reference for future in-depth research in this field.展开更多
How to test the treatments of Chinese medicine（CM） and make them more widely accepted by practitioners of Western medicine and the international healthcare community is a major concern for practitioners and research...How to test the treatments of Chinese medicine（CM） and make them more widely accepted by practitioners of Western medicine and the international healthcare community is a major concern for practitioners and researchers of CM.For centuries,various approaches have been used to identify and measure the efficacy and safety of CM.However,the high-quality evidence related to CM that produced in China is still rare.Over the recent years,evidence-based medicine（EBM） has been increasingly applied to CM,strengthening its theoretical basis.This paper reviews the past and present state of CM,analyzes the status quo,challenges and opportunities of basic research,clinical trials,systematic reviews,clinical practice guidelines and clinical pathways and evidence-based education developed or conducted in China,pointing out how EBM can help to make CM more widely used and recognized worldwide.展开更多
基金Supported by National Natural Science Foundation of ChinaGeneral Program:82074530Heilongjiang Provincial Natural Science Foundation Project:ZD2021H007Heilongjiang Provincial Traditional Chinese Medicine Research Project:ZHY2023-189,ZHY2023-209。
文摘Acupuncture can intervene with and treat vascular dementia(VD)through multiple targets and pathways.The mechanisms of its action involve inhibiting central inflammatory responses,regulating neuronal synaptic plasticity,modulating oxidative stress,reducing neuronal apoptosis,and adjusting cellular autophagy.This paper summarizes researches on the mechanisms of acupuncture treatment for vD over the past decade,aiming to provide theoretical support for the clinical application of acupuncture in treating VD and offer a reference for future in-depth research in this field.
基金Supported by the National Natural Science Foundation of China(No.81430098,81273935,81503459)
文摘How to test the treatments of Chinese medicine（CM） and make them more widely accepted by practitioners of Western medicine and the international healthcare community is a major concern for practitioners and researchers of CM.For centuries,various approaches have been used to identify and measure the efficacy and safety of CM.However,the high-quality evidence related to CM that produced in China is still rare.Over the recent years,evidence-based medicine（EBM） has been increasingly applied to CM,strengthening its theoretical basis.This paper reviews the past and present state of CM,analyzes the status quo,challenges and opportunities of basic research,clinical trials,systematic reviews,clinical practice guidelines and clinical pathways and evidence-based education developed or conducted in China,pointing out how EBM can help to make CM more widely used and recognized worldwide.
