Despite our recognition for biological role and es-sentiality of zinc （Zn）in human nutrtion,clinical as-sessment of Zn status remains highly problematic.Recent animal studies showed the change in plasmaACE （one of ...Despite our recognition for biological role and es-sentiality of zinc （Zn）in human nutrtion,clinical as-sessment of Zn status remains highly problematic.Recent animal studies showed the change in plasmaACE （one of the Zn-enzymes） with addition of Zn invitro was greater corresponding to the feeding periodof Zn deficient diet.In this study,we examinedwhether ACE ratio （increase with Zn/basal Ace）could be a sensitive parameter of Zn nutrition in hu-mans as well.ACE ratio was determined by the in-crement of ACE when added 450μmol/L of ZnSO4.4H<sub>2</sub>O to equivalent amount of plasma.which mightbe the optimal concentration in our preliminary study.In adult patients with intestinal failure receiving homeparenteral nutrition（HPN;100～220μmol/day of Znwas administered） (short bowel syndrome;3,展开更多
文摘Despite our recognition for biological role and es-sentiality of zinc （Zn）in human nutrtion,clinical as-sessment of Zn status remains highly problematic.Recent animal studies showed the change in plasmaACE （one of the Zn-enzymes） with addition of Zn invitro was greater corresponding to the feeding periodof Zn deficient diet.In this study,we examinedwhether ACE ratio （increase with Zn/basal Ace）could be a sensitive parameter of Zn nutrition in hu-mans as well.ACE ratio was determined by the in-crement of ACE when added 450μmol/L of ZnSO4.4H<sub>2</sub>O to equivalent amount of plasma.which mightbe the optimal concentration in our preliminary study.In adult patients with intestinal failure receiving homeparenteral nutrition（HPN;100～220μmol/day of Znwas administered） (short bowel syndrome;3,
