Objective To observe the effect of the Shenqu Zhuyu Decoction(SZD)on varicocele(VC)rats mitophagy and apoptosis in left testis based on PTENinduced putative kinase 1(PINK1)/E3 ubiquitin protein ligase(Parkin)signaling...Objective To observe the effect of the Shenqu Zhuyu Decoction(SZD)on varicocele(VC)rats mitophagy and apoptosis in left testis based on PTENinduced putative kinase 1(PINK1)/E3 ubiquitin protein ligase(Parkin)signaling pathway,and to explore its mechanism.Methods Totally 36 male SD rats were randomly divided into sham operation group,model group and SZD group,12 rats in each group.VC rats model was established by partial ligation of the left renal vein in model group and SZD group.At 48th day after successful molding,the rats in SZD group were treated with SZD(0.7 g/100 g)by gavage,and rats in sham operation group and model group were given the equal volume of normal saline by gavage,twice a day for 60 days.展开更多
Objective To evaluate the diagnostic performance of plasma miR-499 in acute myocardial infarction(AMI)diagnosis.Methods Diagnostic accuracy test was used.The suspected AMI patients,who with chest pain for more than ha...Objective To evaluate the diagnostic performance of plasma miR-499 in acute myocardial infarction(AMI)diagnosis.Methods Diagnostic accuracy test was used.The suspected AMI patients,who with chest pain for more than half an hour and been admitted in the SecondPeople’s Hospital of Wuxi and First People’s Hospital of Chuzhou during October 2010 and July 2011,were consecutively and prospectively enrolled in the present study.Sixty apparently healthy individuals were designed as展开更多
Objective To study the expression changes of IL-1β,FN-α6,IFN-γand TNFR-m18 in peripheral blood within 2 hours in epileptic mice.Methods Semi quantitative real-time PCR was used to test the mRNA expression level of ...Objective To study the expression changes of IL-1β,FN-α6,IFN-γand TNFR-m18 in peripheral blood within 2 hours in epileptic mice.Methods Semi quantitative real-time PCR was used to test the mRNA expression level of IL-1β,FN-α6,IFN-γand TNFR-m18 in peripheral blood from normal and展开更多
文摘Objective To observe the effect of the Shenqu Zhuyu Decoction(SZD)on varicocele(VC)rats mitophagy and apoptosis in left testis based on PTENinduced putative kinase 1(PINK1)/E3 ubiquitin protein ligase(Parkin)signaling pathway,and to explore its mechanism.Methods Totally 36 male SD rats were randomly divided into sham operation group,model group and SZD group,12 rats in each group.VC rats model was established by partial ligation of the left renal vein in model group and SZD group.At 48th day after successful molding,the rats in SZD group were treated with SZD(0.7 g/100 g)by gavage,and rats in sham operation group and model group were given the equal volume of normal saline by gavage,twice a day for 60 days.
文摘Objective To evaluate the diagnostic performance of plasma miR-499 in acute myocardial infarction(AMI)diagnosis.Methods Diagnostic accuracy test was used.The suspected AMI patients,who with chest pain for more than half an hour and been admitted in the SecondPeople’s Hospital of Wuxi and First People’s Hospital of Chuzhou during October 2010 and July 2011,were consecutively and prospectively enrolled in the present study.Sixty apparently healthy individuals were designed as
文摘Objective To study the expression changes of IL-1β,FN-α6,IFN-γand TNFR-m18 in peripheral blood within 2 hours in epileptic mice.Methods Semi quantitative real-time PCR was used to test the mRNA expression level of IL-1β,FN-α6,IFN-γand TNFR-m18 in peripheral blood from normal and
