Neurocognitive functions in obsessive-compulsive disorder patients and their unaffected first-degree relatives

Objective To find the common neurocognitive deficits in patients with obsessive-compulsive disorder (OCD) and their unaffected first-degree relatives (UFDR) and to identify neurocognitive endophenotypes for OCD. Methods Forty patients with OCD,forty UFDR of OCD probands and forty

Brain activation before and after cognitivebehavior therapy in first-episode patients with mildto-moderate major depressive disorder

Objective To explore the neurobiological mechanisms underlying cognitive-behavior therapy(CBT)for major depressive disorder(MDD)by detecting the neural changes of patients following CBT.Methods Thirteen first-episode treatment-naive patients with MDD and 13 matched healthy volunteers underwent fM RI scan.All the patients were treated with 6-week CBT only and scanned again after treatment.A gender recognition