Objective To analyze the differences in the composition and abundance of gut microbiota between patients with active pulmonary tuberculosis and healthy controls,and to identify the specific bacteria as biomarkers to d...Objective To analyze the differences in the composition and abundance of gut microbiota between patients with active pulmonary tuberculosis and healthy controls,and to identify the specific bacteria as biomarkers to distinguish between the two groups.Methods Patients with active pulmonary tuberculosis treated in three municipal designated tuberculosis medical institutions in Sichuan,Jiangsu and Shanghai from September 2017 to September 2019 were selected as case group(n=88),and the healthy people without a history of tuberculosis from the same regions were recruited as control group(n=62).展开更多
Objective To study the iodine nutritional status ofpregnant women in Foshan City,Guangdong Province,and to provide basis for iodine supplementation scientificallyfor them. Methods In 2017, five districtsChancheng,Nanh...Objective To study the iodine nutritional status ofpregnant women in Foshan City,Guangdong Province,and to provide basis for iodine supplementation scientificallyfor them. Methods In 2017, five districtsChancheng,Nanhai,Shunde,Sanshui and Gaoming inFoshan were selected. Each monitoring site was dividedinto five sections according to stratified random samplingin five directions: east,west,south,north and middle.One township (street) was taken in each section,and 20pregnant women were taken from each township( street)to detected their family salt iodine and urinary iodine levels.Results A total of 500 edible salt samples were collectedfrom the families of pregnant women,the medianof salt iodine was 24. 8 mg /kg,the qualified iodized saltconsumption rate was 95. 8% (479 /500),and the iodizedsalt coverage rate was 99. 0% (495 /500).展开更多
Objective To examine the associations of 10 singlenucleotide polymorphisms(SNPs)in peroxisome proliferator-activated receptor(PPARs)gene with lipoprotein(a)level,and to investigate if there is gene-gene interaction am...Objective To examine the associations of 10 singlenucleotide polymorphisms(SNPs)in peroxisome proliferator-activated receptor(PPARs)gene with lipoprotein(a)level,and to investigate if there is gene-gene interaction among the SNPs on lipoprotein(a)level.Methods Totally 644 subjects(234 men and 410 women)were enrolled from Prevention of Multiple Metabolic Disorders and Metabolic Syndrome Study Cohort,which was an urban community survey study conducted in Jiangsu province.Ten SNPs in PPARα(rs135539,rs4253778,展开更多
Objective To compare selenium content in hair samples of children in Kashin-Beck Disease (KBD) areas and control areas,and to provide academic data for KBD control and prevention.Methods In 2011,Longnan,Qingyang,Dingx...Objective To compare selenium content in hair samples of children in Kashin-Beck Disease (KBD) areas and control areas,and to provide academic data for KBD control and prevention.Methods In 2011,Longnan,Qingyang,Dingxi City of KDB areas in Gansu Province were selected as survey point,meanwhile,colleagues of Tianshui City and Lanzhou City were selected as control.展开更多
Objective To investigate the association of adiponectin(APN),free fatty acids(FFA),and insulin resistance(IR)with metabolic syndrome(MS)and its components.Methods In the baseline survey,the subjects were divided into ...Objective To investigate the association of adiponectin(APN),free fatty acids(FFA),and insulin resistance(IR)with metabolic syndrome(MS)and its components.Methods In the baseline survey,the subjects were divided into MS group and the control group展开更多
Objective To study the mechanism of liver fibrosis in rats caused by chronic exposure through drinking water containing sodium arsenite,and to identify the differential proteins via proteomics technique.Methods Totall...Objective To study the mechanism of liver fibrosis in rats caused by chronic exposure through drinking water containing sodium arsenite,and to identify the differential proteins via proteomics technique.Methods Totally 40healthy 8-week-old male Sprague Dawley(SD)rats of specific pathogen free(SPF)grade were randomly divided into 4 groups,which were control group(deionized water),0.68,1.36 and 2.73 mg/kg sodium展开更多
Objective To investigate the effect of haplotype and linkage disequilibrium of PPARγgene rs3856806,rs12490265,rs1797912,and rs1175543 in patients with metabolic syndrome(MS)in Kazakhs of Xinjiang.Methods MALDI-TOF-MS...Objective To investigate the effect of haplotype and linkage disequilibrium of PPARγgene rs3856806,rs12490265,rs1797912,and rs1175543 in patients with metabolic syndrome(MS)in Kazakhs of Xinjiang.Methods MALDI-TOF-MS was used to detect PPAPγgene rs3856806,rs12490265,rs1797912,and rs1175543 genotypes in 489 subjects(including 245 MS and 244 con-展开更多
Objective To examine the incidence and risk factors of violent behaviors in community-dwelling unmedicated patients with severe mental disorders in Shenzhen.Methods The baseline and follow-up data of unmedicated patie...Objective To examine the incidence and risk factors of violent behaviors in community-dwelling unmedicated patients with severe mental disorders in Shenzhen.Methods The baseline and follow-up data of unmedicated patients with severe mental disorders were collected from the Information Management System of Mental Health Prevention and Control in Shenzhen.展开更多
Objective To analyze the arsenic exposure of industrial residents and its influencing factors,so as to provide scientific basis for protecting the health of industrial residents.Methods In 2017,the samples of PM2.5,dr...Objective To analyze the arsenic exposure of industrial residents and its influencing factors,so as to provide scientific basis for protecting the health of industrial residents.Methods In 2017,the samples of PM2.5,drinking water and soil were collected by using cross-sectional survey and were tested for arsenic contents in Xigu District,Lanzhou City.展开更多
文摘Objective To analyze the differences in the composition and abundance of gut microbiota between patients with active pulmonary tuberculosis and healthy controls,and to identify the specific bacteria as biomarkers to distinguish between the two groups.Methods Patients with active pulmonary tuberculosis treated in three municipal designated tuberculosis medical institutions in Sichuan,Jiangsu and Shanghai from September 2017 to September 2019 were selected as case group(n=88),and the healthy people without a history of tuberculosis from the same regions were recruited as control group(n=62).
文摘Objective To study the iodine nutritional status ofpregnant women in Foshan City,Guangdong Province,and to provide basis for iodine supplementation scientificallyfor them. Methods In 2017, five districtsChancheng,Nanhai,Shunde,Sanshui and Gaoming inFoshan were selected. Each monitoring site was dividedinto five sections according to stratified random samplingin five directions: east,west,south,north and middle.One township (street) was taken in each section,and 20pregnant women were taken from each township( street)to detected their family salt iodine and urinary iodine levels.Results A total of 500 edible salt samples were collectedfrom the families of pregnant women,the medianof salt iodine was 24. 8 mg /kg,the qualified iodized saltconsumption rate was 95. 8% (479 /500),and the iodizedsalt coverage rate was 99. 0% (495 /500).
文摘Objective To examine the associations of 10 singlenucleotide polymorphisms(SNPs)in peroxisome proliferator-activated receptor(PPARs)gene with lipoprotein(a)level,and to investigate if there is gene-gene interaction among the SNPs on lipoprotein(a)level.Methods Totally 644 subjects(234 men and 410 women)were enrolled from Prevention of Multiple Metabolic Disorders and Metabolic Syndrome Study Cohort,which was an urban community survey study conducted in Jiangsu province.Ten SNPs in PPARα(rs135539,rs4253778,
文摘Objective To compare selenium content in hair samples of children in Kashin-Beck Disease (KBD) areas and control areas,and to provide academic data for KBD control and prevention.Methods In 2011,Longnan,Qingyang,Dingxi City of KDB areas in Gansu Province were selected as survey point,meanwhile,colleagues of Tianshui City and Lanzhou City were selected as control.
文摘Objective To investigate the association of adiponectin(APN),free fatty acids(FFA),and insulin resistance(IR)with metabolic syndrome(MS)and its components.Methods In the baseline survey,the subjects were divided into MS group and the control group
文摘Objective To study the mechanism of liver fibrosis in rats caused by chronic exposure through drinking water containing sodium arsenite,and to identify the differential proteins via proteomics technique.Methods Totally 40healthy 8-week-old male Sprague Dawley(SD)rats of specific pathogen free(SPF)grade were randomly divided into 4 groups,which were control group(deionized water),0.68,1.36 and 2.73 mg/kg sodium
文摘Objective To investigate the effect of haplotype and linkage disequilibrium of PPARγgene rs3856806,rs12490265,rs1797912,and rs1175543 in patients with metabolic syndrome(MS)in Kazakhs of Xinjiang.Methods MALDI-TOF-MS was used to detect PPAPγgene rs3856806,rs12490265,rs1797912,and rs1175543 genotypes in 489 subjects(including 245 MS and 244 con-
文摘Objective To examine the incidence and risk factors of violent behaviors in community-dwelling unmedicated patients with severe mental disorders in Shenzhen.Methods The baseline and follow-up data of unmedicated patients with severe mental disorders were collected from the Information Management System of Mental Health Prevention and Control in Shenzhen.
文摘Objective To analyze the arsenic exposure of industrial residents and its influencing factors,so as to provide scientific basis for protecting the health of industrial residents.Methods In 2017,the samples of PM2.5,drinking water and soil were collected by using cross-sectional survey and were tested for arsenic contents in Xigu District,Lanzhou City.
