Background Living donor kidney transplantation is becoming popular in China, whereas, in clinical situations, some kidney donors may be sub-optimal, namely marginal living donor. The present study aimed to evaluate th...Background Living donor kidney transplantation is becoming popular in China, whereas, in clinical situations, some kidney donors may be sub-optimal, namely marginal living donor. The present study aimed to evaluate the safety and efficacy of marginal living donor kidney transplantation in a Chinese single center. Methods Between January 2001 and December 2009, 888 kidney transplantations were performed in our center; 149 were living donor kidney transplantations. The living donors and recipients were followed up regularly after the operation. Of the living donors, 30 donors were marginal, who were older than 60 years or suffered from kidney anomaly or some benign diseases. Among the non-marginal living kidney transplantations, 58 donors and recipients had complete peri- operative and follow-up data. We compared the marginal and non-marginal living donor kidney transplantations with regard to donor age, follow-up period, donor＇s serum creatinine at the last follow-up, recipient＇s serum creatinine at the last follow-up, and graft survival at the last follow-up. Results The mean age of donors in the marginal and non-marginal living donors were （55＋9） （37-66） and （43＋12） （30- 59） years. The mean follow-up times of the marginal and non-marginal groups were （26.4＋13.4） months and （28.8＋14.8） months. The donor and recipient serum creatinine levels at the last follow-up were （1.16＋0.20） mg/dl and （1.30＋0.24） mg/dl in the marginal group, and （1.12＋0.32） mg/dl and （1.34＋0.32） mg/dl in the non-marginal group. Three recipients in the marginal group and five recipients in the non-marginal group had acute rejection episodes during the first year. Actuarial 3-year graft survival was 96.7% in the marginal group and 100% in the non-marginal group. No significant differences were detected between the two groups with regard to these data. Conclusion Utilization of highly selective marginal living donors can be a safe, feasible, and effective way for the treatment of patients with end stage renal disease.展开更多
Objective To investigate the prevalences of benign prostatic hyperplasia (BPH) and metabolic syndrome (MS) and to analyze the risk factors for benign prostatic hyperplasia and metabolic syndrome in the elderly.Methods...Objective To investigate the prevalences of benign prostatic hyperplasia (BPH) and metabolic syndrome (MS) and to analyze the risk factors for benign prostatic hyperplasia and metabolic syndrome in the elderly.Methods A total of 490 elderly men undergoing health examination in our hospital from January 2010展开更多
Objective To explore the expression of microRNA-502 ( miRNA-502) and its correlation with clinicopathological features of gastric cancer. Methods A total of 28 gastric cancer patients were enrolled in the study. Quant...Objective To explore the expression of microRNA-502 ( miRNA-502) and its correlation with clinicopathological features of gastric cancer. Methods A total of 28 gastric cancer patients were enrolled in the study. Quantitative real time polymerase chain reaction ( qRT-PCR) was used to detect the expression of miRNA- 502 in cancer tissues and its paired-adjacent normal tissues.展开更多
文摘Background Living donor kidney transplantation is becoming popular in China, whereas, in clinical situations, some kidney donors may be sub-optimal, namely marginal living donor. The present study aimed to evaluate the safety and efficacy of marginal living donor kidney transplantation in a Chinese single center. Methods Between January 2001 and December 2009, 888 kidney transplantations were performed in our center; 149 were living donor kidney transplantations. The living donors and recipients were followed up regularly after the operation. Of the living donors, 30 donors were marginal, who were older than 60 years or suffered from kidney anomaly or some benign diseases. Among the non-marginal living kidney transplantations, 58 donors and recipients had complete peri- operative and follow-up data. We compared the marginal and non-marginal living donor kidney transplantations with regard to donor age, follow-up period, donor＇s serum creatinine at the last follow-up, recipient＇s serum creatinine at the last follow-up, and graft survival at the last follow-up. Results The mean age of donors in the marginal and non-marginal living donors were （55＋9） （37-66） and （43＋12） （30- 59） years. The mean follow-up times of the marginal and non-marginal groups were （26.4＋13.4） months and （28.8＋14.8） months. The donor and recipient serum creatinine levels at the last follow-up were （1.16＋0.20） mg/dl and （1.30＋0.24） mg/dl in the marginal group, and （1.12＋0.32） mg/dl and （1.34＋0.32） mg/dl in the non-marginal group. Three recipients in the marginal group and five recipients in the non-marginal group had acute rejection episodes during the first year. Actuarial 3-year graft survival was 96.7% in the marginal group and 100% in the non-marginal group. No significant differences were detected between the two groups with regard to these data. Conclusion Utilization of highly selective marginal living donors can be a safe, feasible, and effective way for the treatment of patients with end stage renal disease.
文摘Objective To investigate the prevalences of benign prostatic hyperplasia (BPH) and metabolic syndrome (MS) and to analyze the risk factors for benign prostatic hyperplasia and metabolic syndrome in the elderly.Methods A total of 490 elderly men undergoing health examination in our hospital from January 2010
文摘Objective To explore the expression of microRNA-502 ( miRNA-502) and its correlation with clinicopathological features of gastric cancer. Methods A total of 28 gastric cancer patients were enrolled in the study. Quantitative real time polymerase chain reaction ( qRT-PCR) was used to detect the expression of miRNA- 502 in cancer tissues and its paired-adjacent normal tissues.
