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视网膜色素变性患者阅读能力的调查研究:MN-READ图表
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作者 Virgili G. Pierrottet C. +1 位作者 Parmeggiani F. 陈立军 《世界核心医学期刊文摘(眼科学分册)》 2005年第2期30-31,共2页
PURPOSE. To evaluate the relationship between reading performance and severity of disease in patients with retinitis pigmentosa (RP), assessed with routine cl inical psychophysical visual tests. METHODS. Seventy-six c... PURPOSE. To evaluate the relationship between reading performance and severity of disease in patients with retinitis pigmentosa (RP), assessed with routine cl inical psychophysical visual tests. METHODS. Seventy-six consecutive patients w ith RP (145 eyes), with reading acuity of at least 1.6 logMAR (logarithm of the minimum angle of resolution) in at least one eye, were examined. Each patient un derwent a complete ophthalmic evaluation, including visual acuity (Early Treatme nt Diabetic Retinopathy Study ETDRS charts), contrast sensitivity (Pelli-Robs on charts), visual field perimetry (Humphrey central 30-2 full-threshold progr am; Carl Zeiss Meditec, Dublin, CA), and a test of reading acuity, critical prin t size, and maximum reading speed (Minnesota Reading charts MNREAD). RESULTS. Reading acuity was 1.0 logMAR or more in the better eye of all but six (92%) pa tients. Maximum reading speed was better than 100 words per minute in the better eye of 59 (78%) subjects. Moderate to severe reading impairment, defined as re ading acuity of 0.4 logMAR or worse, was observed in the better eye of 47 (62%) patients. EDT RS visual acuity of 0.3 logMAR (20/40)-or worse was 89%sensitive and 66%speci fic when used as a criterion to define reading impairment. Contrast sensitivity and visual acuity correlated significantly with all three reading components, wh ereas mean light sensitivity in the central visual field (6°) demonstrated a hi gher correlation with maximum reading speed. The number of years elapsed since t he diagnosis of RP was a strong negative predictor of reading performance when c linical visual tests were taken into account, whereas a better reading ability c haracterized the patients with RP who had a higher level of education. A reduced reading speed with larger print size was found in 30 eyes (21%). This correlat ed with central light sensitivity, as it was more common among eyes with a mean sensitivity of< 10 dB. CONCLUSIONS. The reading performance of most patients wit h RP is only moderately impaired. It correlates with contrast sensitivity, visua l acuity, and visual field. It should be assessed in all cases, as disability ca n ensue, even when visual acuity is preserved. In patients with RP with poor rea ding performance, there is little potential for high-magnification devices beca use visual field constriction affects the reading rate. 展开更多
关键词 视网膜色素变性 MN-READ 平均光敏感度 对比敏感度 视野计 角分辨率 中心视野 光敏度 评价量表 阅读量
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