Surface plasmon resonance (SPR) sensing is an optical method based on evanescent wave.SPR biosensor can detect interaction of label-free biomolecules in real-time.With further development,it can become a research ins...Surface plasmon resonance (SPR) sensing is an optical method based on evanescent wave.SPR biosensor can detect interaction of label-free biomolecules in real-time.With further development,it can become a research instrument in proteomics.SPR biosensor can be divided intensity measurement and phase measurement,and the latter possesses higher sensitivity than the former one.This paper attempts to summarize the SPR phase detection theory,discuss the major developments,compare the merits and deficiencies of various methods,and look forward to future prospects.展开更多
The electrochemical quartz crystal microbalance (EQCM) is used to investigate the characteristics of the thiolated self-assembled monolayer(SAM) on gold surface.A 5MHz QCM element serves as both the mass-sensitive sen...The electrochemical quartz crystal microbalance (EQCM) is used to investigate the characteristics of the thiolated self-assembled monolayer(SAM) on gold surface.A 5MHz QCM element serves as both the mass-sensitive sensor and the working electrode of the electrochemical system.The 6-mecapto-1-hexanol and and the 16-mer oligonucleotide with a mercaptohexyl group at the 5'-phosphate end are utilized to form the SAM on the gold electrode.The frequency response of the QCM during cyclic voltammetry (CV) scanning and cbronoamperometry are recorded together with the electrochemical current.The experimental results indicates that the frequency response is more sensitive to the surface coverage.Therefore,the response of the EQCM reveals more details of the SAM on gold electrode.It is especially useful for analysing the immobilization quality,such as probe orientation and coverage,of the SAM.展开更多
Complex correlation analysis of remotely sensed multi-spectral images of large scale and series of measurements taken simultaneously on the ground , together with closer attention to the optical characteristics of chl...Complex correlation analysis of remotely sensed multi-spectral images of large scale and series of measurements taken simultaneously on the ground , together with closer attention to the optical characteristics of chlorophyll , yielded quantitative estimates of the chlorophyll distribution , a principal index of nutrient in Yuqiao Reservoir. This is one of the approaches to monitoring nutrients in lakes.展开更多
In recent life science research,identifying and characterizing entire biomolecular interaction networks is prerequisite to understanding cellular processes on a molecular and biophysical level.A surface plasmon resona...In recent life science research,identifying and characterizing entire biomolecular interaction networks is prerequisite to understanding cellular processes on a molecular and biophysical level.A surface plasmon resonance (SPR) imaging interferometer based on spatial phase modulation detection is presented to meet this demand.In this method,the SPR sensing chip surface is illuminated with collimated parallel light beam,and a Wollaston prism is introduced into the reflected light path to produce the interference of polarized light reflected from SPR sensing chip.Information of biomolecular interactions can be obtained by extracting the phase change from the SPR interference patterns.Using our interferometer,we made experiments on a series concentration of NaCl solutions to investigate its detection range,linearity,sensitivity and resolution.The results indicate that the SPR imaging interferometer is mainly sufficient for biomolecular interaction detection.展开更多
High resolution of surface plasmon resonance (SPR) detection is of vital importance.SPR biosensing system resolution is determined by intrinsic sensitivity of biochip and light signal acquisition system.In this articl...High resolution of surface plasmon resonance (SPR) detection is of vital importance.SPR biosensing system resolution is determined by intrinsic sensitivity of biochip and light signal acquisition system.In this article,different signal acquisition system resolutions on photodetector were analyzed based on light intensity and phase detection.Result shows that charge coupled device (CCD) with larger numbers of pixels is potential to achieve higher detection resolution.A 64 pixel line array CCD and a 12 bit ADC can achieve resolution of 10^(-7) refractive index unit (RIU).In array detection mode,increasing of detection throughput is at the cost of decreasing system resolution.Simulation analysis indicates that,if noise is taken into account,phase modulation methods are capable of providing better noise reduction performance than intensity methods.展开更多
In cases of measurement,like the beverage discrimination or waste water monitoring,since sensors with direct measuring for specific variables cannot be practically applied,the interest in soft sensor technology,which ...In cases of measurement,like the beverage discrimination or waste water monitoring,since sensors with direct measuring for specific variables cannot be practically applied,the interest in soft sensor technology,which is based on the acquisition and analysis for a lot of information variables,has rapidly increased.This article presents a novel soft sensor which activates a voltage signal between two specially-designed electrodes,inside the Chinese tea solution,and measures the produced current.The proposed sensor discriminated four different kinds of tea,and the dissolution processes of two of them are described as curves on a bidimensional plane.The results indicate that the proposed approach can also be adapted in characterization or discrimination for other solutions.展开更多
The method of error correction is one of key techniques of parallel robot. A new method of end error correction of 6-HTRT parallel robot is presented for engineering and researching on correlative theory of 6-HTRT par...The method of error correction is one of key techniques of parallel robot. A new method of end error correction of 6-HTRT parallel robot is presented for engineering and researching on correlative theory of 6-HTRT parallel robot. The method need calculate many kinematics equations of parallel robot such as position back solution, velocity Jacobin, position forward solution and error Jacobin. New methods presented for solving these questions are simpler and fitter for programming and calculating, because former methods are too complex to use in engineering. These questions may be solved by iterative method of numerical value which has fast velocity of calculating. These new methods may be used in other mechanism of parallel robot too, and so have wider using value. The experimental results demonstrate that the system may satisfy entirely high technical request and fit for engineering in new measures.展开更多
In this paper,a dynamic linear detecting method,that the non-linear coefficient NL% was led and the non-linearity of data were estimated continuously and dynamically and determined when NL% exceeded reference value (...In this paper,a dynamic linear detecting method,that the non-linear coefficient NL% was led and the non-linearity of data were estimated continuously and dynamically and determined when NL% exceeded reference value (5%),was used for data processing and could solve the problem caused by the phenomenon of substrate depleting occurred following the redox reaction in portable blood sugar analyzer.By contrast to the conventional end-point method,the dynamic linear detecting method is based on multipoint data collecting.Experiments of measuring the calibration glucose solution with 8 various concentrations from 50 mg/dl to 400 mg/dl were carried out with the analyzer developed by our group.The linear regression curve,whose correlation for the data was 0.9995 and the residual was 2.8080,were obtained.The obtained correlation,residual, and the computation workload are all fit for the portable blood sugar analyzer.展开更多
Scheduling is one of the key factors of affecting the flexibility of an FMS. In this paper, scheduling problems in FMS, including description, solving and rescheduling, are discussed in detail.
Acoustic telemetry along the drill string helps to know the physical and chemical characteristics of the formation and drilling fluid.A time-domain algorithm is developed for the propagation of one-dimensional axial s...Acoustic telemetry along the drill string helps to know the physical and chemical characteristics of the formation and drilling fluid.A time-domain algorithm is developed for the propagation of one-dimensional axial stress waves with the inner and outer viscous fluid.The algorithm simulates the passbands,stopbands and spikes due to the presence of the discontinuous boundaries of drill string.Then the effects of transmitted pulses and transceivers on acoustic transmission are analysed.The simulated results show that the raised cosine pulses and optimal placements of transceivers improve system performance.Moreover,dual PZT receivers can exclude signals propagating in a direction opposite to the transmitted signals. It is obvious that the uses of the available modeling and signal processing techniques can make the drill string as a waveguide for transmitting information at high data rates.展开更多
The moisture content measurement of human skin is a significant way to assess skin conditions and diagnose diseases that influence skin function.The necessity of evaluating the efficacy of a cosmetic product makes it ...The moisture content measurement of human skin is a significant way to assess skin conditions and diagnose diseases that influence skin function.The necessity of evaluating the efficacy of a cosmetic product makes it important to improve the accuracy and reproducibility of the measurement.A pair of interdigitated gold electrodes was fabricated on the printed circuit board (PCB) substrate and utilized directly in contact with the measured skin.A square-wave voltage at a single frequency was applied to the electrodes and the corresponding response current was measured to get the equivalent impedance of human skin.Since it's easy to generate and control a square-wave signal by digital electric circuits,this method is suitable to be used in the portable application.The experimental results indicate that good repeatability and satisfied accuracy can be obtained by this method.展开更多
1 Introduction 1.1 Advantages of DOE 1)High diffraction efficiency; 2)Dispersive; 3)More selectivity of designing parameters; 4)More selectivity of primary materials; 5)Can make components miniature,forming array and ...1 Introduction 1.1 Advantages of DOE 1)High diffraction efficiency; 2)Dispersive; 3)More selectivity of designing parameters; 4)More selectivity of primary materials; 5)Can make components miniature,forming array and integration. 1.2 1.3 megapixel triplet plastic mobile展开更多
文摘Surface plasmon resonance (SPR) sensing is an optical method based on evanescent wave.SPR biosensor can detect interaction of label-free biomolecules in real-time.With further development,it can become a research instrument in proteomics.SPR biosensor can be divided intensity measurement and phase measurement,and the latter possesses higher sensitivity than the former one.This paper attempts to summarize the SPR phase detection theory,discuss the major developments,compare the merits and deficiencies of various methods,and look forward to future prospects.
文摘The electrochemical quartz crystal microbalance (EQCM) is used to investigate the characteristics of the thiolated self-assembled monolayer(SAM) on gold surface.A 5MHz QCM element serves as both the mass-sensitive sensor and the working electrode of the electrochemical system.The 6-mecapto-1-hexanol and and the 16-mer oligonucleotide with a mercaptohexyl group at the 5'-phosphate end are utilized to form the SAM on the gold electrode.The frequency response of the QCM during cyclic voltammetry (CV) scanning and cbronoamperometry are recorded together with the electrochemical current.The experimental results indicates that the frequency response is more sensitive to the surface coverage.Therefore,the response of the EQCM reveals more details of the SAM on gold electrode.It is especially useful for analysing the immobilization quality,such as probe orientation and coverage,of the SAM.
文摘Complex correlation analysis of remotely sensed multi-spectral images of large scale and series of measurements taken simultaneously on the ground , together with closer attention to the optical characteristics of chlorophyll , yielded quantitative estimates of the chlorophyll distribution , a principal index of nutrient in Yuqiao Reservoir. This is one of the approaches to monitoring nutrients in lakes.
文摘In recent life science research,identifying and characterizing entire biomolecular interaction networks is prerequisite to understanding cellular processes on a molecular and biophysical level.A surface plasmon resonance (SPR) imaging interferometer based on spatial phase modulation detection is presented to meet this demand.In this method,the SPR sensing chip surface is illuminated with collimated parallel light beam,and a Wollaston prism is introduced into the reflected light path to produce the interference of polarized light reflected from SPR sensing chip.Information of biomolecular interactions can be obtained by extracting the phase change from the SPR interference patterns.Using our interferometer,we made experiments on a series concentration of NaCl solutions to investigate its detection range,linearity,sensitivity and resolution.The results indicate that the SPR imaging interferometer is mainly sufficient for biomolecular interaction detection.
文摘High resolution of surface plasmon resonance (SPR) detection is of vital importance.SPR biosensing system resolution is determined by intrinsic sensitivity of biochip and light signal acquisition system.In this article,different signal acquisition system resolutions on photodetector were analyzed based on light intensity and phase detection.Result shows that charge coupled device (CCD) with larger numbers of pixels is potential to achieve higher detection resolution.A 64 pixel line array CCD and a 12 bit ADC can achieve resolution of 10^(-7) refractive index unit (RIU).In array detection mode,increasing of detection throughput is at the cost of decreasing system resolution.Simulation analysis indicates that,if noise is taken into account,phase modulation methods are capable of providing better noise reduction performance than intensity methods.
文摘In cases of measurement,like the beverage discrimination or waste water monitoring,since sensors with direct measuring for specific variables cannot be practically applied,the interest in soft sensor technology,which is based on the acquisition and analysis for a lot of information variables,has rapidly increased.This article presents a novel soft sensor which activates a voltage signal between two specially-designed electrodes,inside the Chinese tea solution,and measures the produced current.The proposed sensor discriminated four different kinds of tea,and the dissolution processes of two of them are described as curves on a bidimensional plane.The results indicate that the proposed approach can also be adapted in characterization or discrimination for other solutions.
文摘The method of error correction is one of key techniques of parallel robot. A new method of end error correction of 6-HTRT parallel robot is presented for engineering and researching on correlative theory of 6-HTRT parallel robot. The method need calculate many kinematics equations of parallel robot such as position back solution, velocity Jacobin, position forward solution and error Jacobin. New methods presented for solving these questions are simpler and fitter for programming and calculating, because former methods are too complex to use in engineering. These questions may be solved by iterative method of numerical value which has fast velocity of calculating. These new methods may be used in other mechanism of parallel robot too, and so have wider using value. The experimental results demonstrate that the system may satisfy entirely high technical request and fit for engineering in new measures.
文摘In this paper,a dynamic linear detecting method,that the non-linear coefficient NL% was led and the non-linearity of data were estimated continuously and dynamically and determined when NL% exceeded reference value (5%),was used for data processing and could solve the problem caused by the phenomenon of substrate depleting occurred following the redox reaction in portable blood sugar analyzer.By contrast to the conventional end-point method,the dynamic linear detecting method is based on multipoint data collecting.Experiments of measuring the calibration glucose solution with 8 various concentrations from 50 mg/dl to 400 mg/dl were carried out with the analyzer developed by our group.The linear regression curve,whose correlation for the data was 0.9995 and the residual was 2.8080,were obtained.The obtained correlation,residual, and the computation workload are all fit for the portable blood sugar analyzer.
基金National Post Doctor Science Foundation of China
文摘Scheduling is one of the key factors of affecting the flexibility of an FMS. In this paper, scheduling problems in FMS, including description, solving and rescheduling, are discussed in detail.
文摘Acoustic telemetry along the drill string helps to know the physical and chemical characteristics of the formation and drilling fluid.A time-domain algorithm is developed for the propagation of one-dimensional axial stress waves with the inner and outer viscous fluid.The algorithm simulates the passbands,stopbands and spikes due to the presence of the discontinuous boundaries of drill string.Then the effects of transmitted pulses and transceivers on acoustic transmission are analysed.The simulated results show that the raised cosine pulses and optimal placements of transceivers improve system performance.Moreover,dual PZT receivers can exclude signals propagating in a direction opposite to the transmitted signals. It is obvious that the uses of the available modeling and signal processing techniques can make the drill string as a waveguide for transmitting information at high data rates.
文摘The moisture content measurement of human skin is a significant way to assess skin conditions and diagnose diseases that influence skin function.The necessity of evaluating the efficacy of a cosmetic product makes it important to improve the accuracy and reproducibility of the measurement.A pair of interdigitated gold electrodes was fabricated on the printed circuit board (PCB) substrate and utilized directly in contact with the measured skin.A square-wave voltage at a single frequency was applied to the electrodes and the corresponding response current was measured to get the equivalent impedance of human skin.Since it's easy to generate and control a square-wave signal by digital electric circuits,this method is suitable to be used in the portable application.The experimental results indicate that good repeatability and satisfied accuracy can be obtained by this method.
文摘1 Introduction 1.1 Advantages of DOE 1)High diffraction efficiency; 2)Dispersive; 3)More selectivity of designing parameters; 4)More selectivity of primary materials; 5)Can make components miniature,forming array and integration. 1.2 1.3 megapixel triplet plastic mobile
