Objective This study was undertaken to determine maternal and perinat al outcom es after expectant management of severe preeclampsia between 24 and 33 weeksge station. Study design A prospective observational study ...Objective This study was undertaken to determine maternal and perinat al outcom es after expectant management of severe preeclampsia between 24 and 33 weeksge station. Study design A prospective observational study of 239 women with severe preeclamptic and undelivered after antenatal steroid prophylaxis was performed. Pregnancy prolongation and maternal and perinatal morbidities were analyzed acc ording to the gestational age at time of expectant management: 24 to 28, 29 to 3 1, and 32 to 33 weeks. Statistical analysis was performed by Student t test and χ2 test. Results The days of pregnancy prolongation were significantly higher a mong those managed at less than 29 weeks (6) compared with the other groups (4). There were 13 perinatal deaths: 12 in those managed at less than 29 weeks and 1 in those managed at 29 to 31 weeks. Neonatal morbidities were significantly hig her among those managed at less than 29 weeks compared with the other groups. Th ere were no instances of maternal death or eclampsia. Maternal morbidities were similar among the groups. Conclusion Expectant management of severe preeclampsia at 24 to 33 weeks in a tertiary care center is associated with good perinatal o utcome with a minimal risk for the mother.展开更多
Objective. The purpose of this study was to examine sentinel lymph no de (SLN) detection in patients with early stage cervical cancer using 99mTc phytate and p atent blue dye and to compare our method with published f...Objective. The purpose of this study was to examine sentinel lymph no de (SLN) detection in patients with early stage cervical cancer using 99mTc phytate and p atent blue dye and to compare our method with published findings utilizing other radioisotopic tracers. Patients and methods. A total of 20 consecutive patients with cervical cancer scheduled for radical hysterectomy and total pelvic lympha denectomy at our hospital underwent SLN detection study. The day before surgery, lymphoscintigraphywas performedwith injection of 99m-technetium (99mTc)-label ed phytate into the uterine cervix. At surgery, patients underwent lymphatic map ping with a gamma detecting probe and patent blue injected into the same points as the phytate solution. Results. At least one positive node was detected in 18 patients (90%). A total of 46 sentinel nodeswere detected (mean, 2.3; range, 1 -5). Most sentinel nodes were in one of the following sites: external iliac (21 nodes), obturator (15 nodes), and parametrial (7 nodes). Eleven (24%) sentinel nodes were detected only through radioactivity and two (4%)-were detected onl y with blue dye. The sensitivity, specificity, and negative predictive value for SLN detection were all 100%. Nine published studies involving 295 patients had a summarized detection rate of 85%. Summarized sensitivity, specificity, and n egative predictive value were 93%, 100%, and 99%, respectively. Conclusion. C ombination of 99mTc phytate and patent blue is effective in SLN detection in ear ly stage cervical cancer.展开更多
No nerve fibers are found in endometr iomasor in the en-dometrioma-containing ovaries.These findings are con-sistent with our previous report that no correlation exists between the presence of nerve fibers and endomet...No nerve fibers are found in endometr iomasor in the en-dometrioma-containing ovaries.These findings are con-sistent with our previous report that no correlation exists between the presence of nerve fibers and endometriosis.展开更多
文摘Objective This study was undertaken to determine maternal and perinat al outcom es after expectant management of severe preeclampsia between 24 and 33 weeksge station. Study design A prospective observational study of 239 women with severe preeclamptic and undelivered after antenatal steroid prophylaxis was performed. Pregnancy prolongation and maternal and perinatal morbidities were analyzed acc ording to the gestational age at time of expectant management: 24 to 28, 29 to 3 1, and 32 to 33 weeks. Statistical analysis was performed by Student t test and χ2 test. Results The days of pregnancy prolongation were significantly higher a mong those managed at less than 29 weeks (6) compared with the other groups (4). There were 13 perinatal deaths: 12 in those managed at less than 29 weeks and 1 in those managed at 29 to 31 weeks. Neonatal morbidities were significantly hig her among those managed at less than 29 weeks compared with the other groups. Th ere were no instances of maternal death or eclampsia. Maternal morbidities were similar among the groups. Conclusion Expectant management of severe preeclampsia at 24 to 33 weeks in a tertiary care center is associated with good perinatal o utcome with a minimal risk for the mother.
文摘Objective. The purpose of this study was to examine sentinel lymph no de (SLN) detection in patients with early stage cervical cancer using 99mTc phytate and p atent blue dye and to compare our method with published findings utilizing other radioisotopic tracers. Patients and methods. A total of 20 consecutive patients with cervical cancer scheduled for radical hysterectomy and total pelvic lympha denectomy at our hospital underwent SLN detection study. The day before surgery, lymphoscintigraphywas performedwith injection of 99m-technetium (99mTc)-label ed phytate into the uterine cervix. At surgery, patients underwent lymphatic map ping with a gamma detecting probe and patent blue injected into the same points as the phytate solution. Results. At least one positive node was detected in 18 patients (90%). A total of 46 sentinel nodeswere detected (mean, 2.3; range, 1 -5). Most sentinel nodes were in one of the following sites: external iliac (21 nodes), obturator (15 nodes), and parametrial (7 nodes). Eleven (24%) sentinel nodes were detected only through radioactivity and two (4%)-were detected onl y with blue dye. The sensitivity, specificity, and negative predictive value for SLN detection were all 100%. Nine published studies involving 295 patients had a summarized detection rate of 85%. Summarized sensitivity, specificity, and n egative predictive value were 93%, 100%, and 99%, respectively. Conclusion. C ombination of 99mTc phytate and patent blue is effective in SLN detection in ear ly stage cervical cancer.
文摘No nerve fibers are found in endometr iomasor in the en-dometrioma-containing ovaries.These findings are con-sistent with our previous report that no correlation exists between the presence of nerve fibers and endometriosis.