Background: The prevalence of child obesity is increasing rapidly worldwide as well as Turkey due to skipped main meals and increased snacking. The objectives were to study the prevalence rates of overweight and obesi...Background: The prevalence of child obesity is increasing rapidly worldwide as well as Turkey due to skipped main meals and increased snacking. The objectives were to study the prevalence rates of overweight and obesity in a group of Turkish children, and to analyze the relationship between eating habits and lifestyle and obesity. Methods: The study was carried out in 6 schools in urban regions in the city of Eskisehir, Western Turkey between February and May2008. Atotal of 1421 students aged 7 - 14 years (708 boys and 713 girls) were examined. Eating habits and life-style were obtained by evaluation of a standard set of 15 questions prepared using the literature. Results: Most obese students reported having a snack in the afternoon, not spending at least five hours of leisure time per week in physical activities, being high income level, that their mother’ education level was university, eating less fruits, eating less vegetables, having more dessert after any meal, eating more potato chips, watching television more, living a physically active life less, less breast feeding, that their father consumed alcohol, that their father was overweight/ obese, their mother wase overweight/obese (statistically important relationships for each one). Conclusions: A small portion of 7 - 14-year-old Turkish children are at increased health risk owing to overweight and obesity in an urban po- pulation in a developing country.展开更多
The number of diabetic patients has recently been increasing all over the world together with lifestyle changes including sedentary life and high-calorie diet intake, and as a result the increase in these suffering fr...The number of diabetic patients has recently been increasing all over the world together with lifestyle changes including sedentary life and high-calorie diet intake, and as a result the increase in these suffering from diabetes mellitus has become a global issue. Diabetic animal models play a key role in bettering our understanding of the pathophysiology of diabetes and in developing new therapies for the disease. Diabetes is classified into two types, type 1 and type 2, and type 2 diabetes is chiefly caused by a depletion of insulin secretion in the pancreas and insulin resistance in peripheral tissues. The Goto-Kakizaki (GK) rat and the Spontaneously Diabetic Torii (SDT) rat are genetic non-obese type 2 diabetic models, and the both rats are considered to be suitable models for investigating the etiology of the depletion of insulin secretion and impaired glucose tolerance. In this review, we overviewed the outline of pathophysiological features in GK rats and SDT rats, including biological parameters and pharmacological responses.展开更多
Research Background and Purpose: The number of diabetic patients is rapidly increasing, making it crucial to find methods to prevent diabetic retinopathy (DR), a leading cause of blindness. We investigated the effects...Research Background and Purpose: The number of diabetic patients is rapidly increasing, making it crucial to find methods to prevent diabetic retinopathy (DR), a leading cause of blindness. We investigated the effects of prophylactic pattern scanning laser retinal photocoagulation on DR development in Spontaneously Diabetic Torii (SDT) fatty rats as a new prevention approach. Methods: Photocoagulation was applied to the right eyes of 8-week-old Spontaneously Diabetic Torii (SDT) fatty rats, with the left eyes serving as untreated controls. Electroretinography at 9 and 39 weeks of age and pathological examinations, including immunohistochemistry for vascular endothelial growth factor and glial fibrillary acidic protein at 24 and 40 weeks of age, were performed on both eyes. Results: There were no significant differences in amplitude and prolongation of the OP waves between the right and left eyes in SDT fatty rats at 39 weeks of age. Similarly, no significant differences in pathology and immunohistochemistry were observed between the right and left eyes in SDT fatty rats at 24 and 40 weeks of age. Conclusion: Prophylactic pattern scanning retinal laser photocoagulation did not affect the development of diabetic retinopathy in SDT fatty rats.展开更多
文摘Background: The prevalence of child obesity is increasing rapidly worldwide as well as Turkey due to skipped main meals and increased snacking. The objectives were to study the prevalence rates of overweight and obesity in a group of Turkish children, and to analyze the relationship between eating habits and lifestyle and obesity. Methods: The study was carried out in 6 schools in urban regions in the city of Eskisehir, Western Turkey between February and May2008. Atotal of 1421 students aged 7 - 14 years (708 boys and 713 girls) were examined. Eating habits and life-style were obtained by evaluation of a standard set of 15 questions prepared using the literature. Results: Most obese students reported having a snack in the afternoon, not spending at least five hours of leisure time per week in physical activities, being high income level, that their mother’ education level was university, eating less fruits, eating less vegetables, having more dessert after any meal, eating more potato chips, watching television more, living a physically active life less, less breast feeding, that their father consumed alcohol, that their father was overweight/ obese, their mother wase overweight/obese (statistically important relationships for each one). Conclusions: A small portion of 7 - 14-year-old Turkish children are at increased health risk owing to overweight and obesity in an urban po- pulation in a developing country.
文摘The number of diabetic patients has recently been increasing all over the world together with lifestyle changes including sedentary life and high-calorie diet intake, and as a result the increase in these suffering from diabetes mellitus has become a global issue. Diabetic animal models play a key role in bettering our understanding of the pathophysiology of diabetes and in developing new therapies for the disease. Diabetes is classified into two types, type 1 and type 2, and type 2 diabetes is chiefly caused by a depletion of insulin secretion in the pancreas and insulin resistance in peripheral tissues. The Goto-Kakizaki (GK) rat and the Spontaneously Diabetic Torii (SDT) rat are genetic non-obese type 2 diabetic models, and the both rats are considered to be suitable models for investigating the etiology of the depletion of insulin secretion and impaired glucose tolerance. In this review, we overviewed the outline of pathophysiological features in GK rats and SDT rats, including biological parameters and pharmacological responses.
文摘Research Background and Purpose: The number of diabetic patients is rapidly increasing, making it crucial to find methods to prevent diabetic retinopathy (DR), a leading cause of blindness. We investigated the effects of prophylactic pattern scanning laser retinal photocoagulation on DR development in Spontaneously Diabetic Torii (SDT) fatty rats as a new prevention approach. Methods: Photocoagulation was applied to the right eyes of 8-week-old Spontaneously Diabetic Torii (SDT) fatty rats, with the left eyes serving as untreated controls. Electroretinography at 9 and 39 weeks of age and pathological examinations, including immunohistochemistry for vascular endothelial growth factor and glial fibrillary acidic protein at 24 and 40 weeks of age, were performed on both eyes. Results: There were no significant differences in amplitude and prolongation of the OP waves between the right and left eyes in SDT fatty rats at 39 weeks of age. Similarly, no significant differences in pathology and immunohistochemistry were observed between the right and left eyes in SDT fatty rats at 24 and 40 weeks of age. Conclusion: Prophylactic pattern scanning retinal laser photocoagulation did not affect the development of diabetic retinopathy in SDT fatty rats.
