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ECMO基础上表面活性物质替代疗法不能改善新生儿先天性膈疝的预后
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作者 Colby C. E. 肖莉 《世界核心医学期刊文摘(儿科学分册)》 2005年第4期49-50,共2页
背景/目的:对于患先天性膈疝(CDH)的新生儿来说,呼吸衰竭可能部分是因原发性或继发性的表面活性物质缺乏引起。在CDH和呼吸衰竭的新生儿中,对表面活性物质替代疗法最佳方法的认识有限。本研究的目的是确定在体外膜式氧合(ECMO)的基础上。
关键词 表面活性物质 ECMO 先天性膈疝 体外膜式氧合 呼吸衰竭 EXTRACORPOREAL 临床过程 严重异常 GESTATIONAL HERNIA
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低危人群的剖宫产分娩率及新生儿发病率
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作者 Gould J.B. Danielsen B. +1 位作者 Korst L.M. 成健 《世界核心医学期刊文摘(妇产科学分册)》 2005年第8期36-37,共2页
OBJECTIVE: To estimate the relationship between case-mix adjusted cesarean delivery rates and neonatal morbidity and mortality in infants born to low-risk mothers. METHODS: This retrospective cohort study used vital a... OBJECTIVE: To estimate the relationship between case-mix adjusted cesarean delivery rates and neonatal morbidity and mortality in infants born to low-risk mothers. METHODS: This retrospective cohort study used vital and administrative data for 748,604 California singletons born without congenital abnormalities in 1998-2000. A total of 282 institutions was classified as average-, low-, or high-cesarean delivery hospitals based on their cesarean delivery rate for mothers without a previous cesarean delivery, in labor at term, with no evidence of maternal, fetal, or placental complications. Neonatal mortality, diagnoses, and therapeutic interventions determined by International Classification of Diseases, 9th Revision, Clinical Modification codes, and neonatal length of stay were compared across these hospital groupings. RESULTS: Compared with average-cesarean delivery-rate hospi tals, infants born to low-risk mothers at low-cesarean delivery hospitals had increased fetal hemorrhage, birth asphyxia, meconium aspiration syndrome, feeding problems, and electrolyte abnormalities (P <.02). Infused medication, pressors, transfusion for shock, mechanical ventilation, and length of stay were also increased (P <.001). This suggests that some infants born in low-cesarean delivery hospitals might have benefited from cesarean delivery. Infants delivered at high-cesarean delivery hospitals demonstrated increased fetal hemorrhage, asphyxia, birth trauma, electrolyte abnormalities, and use of mechanical ventilation (P <.001), suggesting that high cesarean delivery rates themselves are not protective. CONCLUSION: Neonatal morbidity is increased in infants born to low-risk women who deliver at both low-and high-cesarean delivery-rate hospitals. The quality of perinatal care should be assessed in these outlier hospitals. 展开更多
关键词 剖宫产分娩 新生儿发病率 低危人群 胎粪吸入综合征 围生期 足月分娩 喂养问题 出生婴儿 先天性疾病 药物输注
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