Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segment...Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segments of double-stranded RNA (segments A and B), targets B lymphocytes of bursa of Fabricious leading to immunosuppression. In Pakistan,poultry farming is the second biggest industry and IBD is the second biggest disease threating the poultry sector.However.展开更多
Alzheimer’s disease(AD)is the most common cause of dementia.Although AD was initially considered to be a cell autonomous neurodegenerative disorder,marked neuroinflammation has been observed in brains of AD patients....Alzheimer’s disease(AD)is the most common cause of dementia.Although AD was initially considered to be a cell autonomous neurodegenerative disorder,marked neuroinflammation has been observed in brains of AD patients.Genetic and molecular biological findings have suggested the central nervous system(CNS)inflammatory processes to be involved in the etiopathogenesis of AD,in which the activated microglia play a key role.展开更多
基金supported by the National Key Research and Development Program of China (Nos. 2016YFE0203200, 2017YFD0500704)the Major Project of National Natural Science Foundation of China (No. 31430087)the Modern Agro-industry Technology Research System (No. CARS-41-G15)
文摘Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segments of double-stranded RNA (segments A and B), targets B lymphocytes of bursa of Fabricious leading to immunosuppression. In Pakistan,poultry farming is the second biggest industry and IBD is the second biggest disease threating the poultry sector.However.
基金mainly supported in part by a grant from the Japan Agency for Medical Research and Developm ent(AMED)(to T.T.)partially by Grants-in-Aid(Nos.15 K09319 and 18 K07506 to T.K.,No.20 K16605 to T.O.,No.18K15461 to H.T.)from the Ministry of Education,Culture,Sports,Science and Technology of Japanresearch grants from Dainippon Sumitomo Pharma in 2018(to T.O.)and 2017(to T.K.).
文摘Alzheimer’s disease(AD)is the most common cause of dementia.Although AD was initially considered to be a cell autonomous neurodegenerative disorder,marked neuroinflammation has been observed in brains of AD patients.Genetic and molecular biological findings have suggested the central nervous system(CNS)inflammatory processes to be involved in the etiopathogenesis of AD,in which the activated microglia play a key role.
