Contents1.Introduction2.Methods2.1 Guideline project group2.2 Registration and methodology2.3 Guideline process2.3.1 Formulation of clinical questions2.3.2 Systematic literature review2.3.3 Consensus on recommendation...Contents1.Introduction2.Methods2.1 Guideline project group2.2 Registration and methodology2.3 Guideline process2.3.1 Formulation of clinical questions2.3.2 Systematic literature review2.3.3 Consensus on recommendations3.Recommendations3.1 General principles3.2 Drug delivery,reception and storage3.3 Dispensing of antineoplastics3.4 Administration and carrying of antineoplastics3.5 Prevention measures for blood,excreta(urine and feces),and vomitus of patients3.6 Medical waste disposal4.Discussion5.Conclusions 1.Introduction The exposure of nurses,pharmacists,physicians,laboratory technicians,drug transportationstaff,,patients and caregivers in medical institutions to antineoplastics is a potential health hazard.Furthermore,these antineoplastics are potential contaminants if disposed inappropriately to the environment,thus making it an issue of immense concern in medical safety.A drug is declared hazardous if it shows one or more of the following six impacts on humans or animals:carcinogenicity,teratogenicity or other developmental toxicity,reproductive toxicity,organ toxicity at low doses,and genotoxicity.Hazardous drugs also include new drugs possessing structural and toxicity profiles similar to the existing hazardous drugs(1).展开更多
文摘Contents1.Introduction2.Methods2.1 Guideline project group2.2 Registration and methodology2.3 Guideline process2.3.1 Formulation of clinical questions2.3.2 Systematic literature review2.3.3 Consensus on recommendations3.Recommendations3.1 General principles3.2 Drug delivery,reception and storage3.3 Dispensing of antineoplastics3.4 Administration and carrying of antineoplastics3.5 Prevention measures for blood,excreta(urine and feces),and vomitus of patients3.6 Medical waste disposal4.Discussion5.Conclusions 1.Introduction The exposure of nurses,pharmacists,physicians,laboratory technicians,drug transportationstaff,,patients and caregivers in medical institutions to antineoplastics is a potential health hazard.Furthermore,these antineoplastics are potential contaminants if disposed inappropriately to the environment,thus making it an issue of immense concern in medical safety.A drug is declared hazardous if it shows one or more of the following six impacts on humans or animals:carcinogenicity,teratogenicity or other developmental toxicity,reproductive toxicity,organ toxicity at low doses,and genotoxicity.Hazardous drugs also include new drugs possessing structural and toxicity profiles similar to the existing hazardous drugs(1).