Allogenic haematological stem cell transplantation (allo-SCT) from a human leukocyte antigen (HLA) matched related or unrelated donor is used as a curative therapy for a large number of malignant and non-malignant hae...Allogenic haematological stem cell transplantation (allo-SCT) from a human leukocyte antigen (HLA) matched related or unrelated donor is used as a curative therapy for a large number of malignant and non-malignant haematological diseases. The curative effect of allo-SCT is achieved by graft versus leukaemia effect while the downside of the graft versus patient activity is the graft-versus-host-disease (GVHD), a major reason for mortality and morbidity. The search of articles for this review had been accomplished using Ovid, Medline, Embase, Pubmed and was supplemented by retrieving cross references also. Electronic literature search for English language articles with full text access was performed using graft versus host disease, ocular, management, dry eyes as key words. This review has been intended to explicate the classification, pathogenesis, risk factors and management of ocular graft versus host disease.展开更多
Cysticercosis is a preventable and eradicable cause of blindness endemic in the Indian subcontinent, South- East Asia and other developing countries. Ocular and orbital cysticercosis has varied presentations depending...Cysticercosis is a preventable and eradicable cause of blindness endemic in the Indian subcontinent, South- East Asia and other developing countries. Ocular and orbital cysticercosis has varied presentations depending upon the site of involvement, number of lesion and the host immune response. In this article we present a review of the various clinical manifestations, diagnosis and management protocol for orbital and ocular cysticercosis. Owing to its varied presentation, cysticercosis may pose a diagnostic challenge to the health professionals. Early diagnosis and management can prevent the vision loss and optimize visual outcomes.展开更多
Dear editor,Globe luxation is defined as complete prolapse of the eyeball outside the orbital cavity with eyelids closed behind the eyeball.Broadly,globe luxation can be categorized as traumatic,spontaneous or volunta...Dear editor,Globe luxation is defined as complete prolapse of the eyeball outside the orbital cavity with eyelids closed behind the eyeball.Broadly,globe luxation can be categorized as traumatic,spontaneous or voluntary;males are affected more than females with an average age of 30 years.[1]Traumatic globe luxation is quite rare in children,with most cases reported in the adult age group.Orbital fracture comprises 5%to 25%of all facial fractures in the paediatric age group.[2]In cases with luxation of globe,immediate reposition is crucial for globe and vision salvage.We describe the clinical features,evaluation,and management of globe luxation present at birth following normal vaginal delivery conducted elsewhere.展开更多
In patients with lagophthalmos due to eyelid trauma,it is imperative to ensure adequate closure of the eye to protect the ocular surface.Sometimes it is difficult to surgically close eyelids by conventional methods of...In patients with lagophthalmos due to eyelid trauma,it is imperative to ensure adequate closure of the eye to protect the ocular surface.Sometimes it is difficult to surgically close eyelids by conventional methods of tarsorrhaphy,such as intermarginal suture tarsorrhaphy,Week’s tarsorrhaphy,and tongue-in-groove tarsorrhaphy.We need intact eyelid tissues to perform these procedures and might not be possible in patients with severe lagophthalmos due to lost/damaged eyelid tissues either due to deficient length of tissues or increased tension at the wound site,which can result in surgical failure.[1]展开更多
Purpose: To conduct a randomized prospective clinical trial to compare primary vitrectomy without scleral buckling versus conventional scleral buckling surger y in pseudophakic primary retinal detachment (PPRD) in ter...Purpose: To conduct a randomized prospective clinical trial to compare primary vitrectomy without scleral buckling versus conventional scleral buckling surger y in pseudophakic primary retinal detachment (PPRD) in terms of anatomic attachm ent rate, functional outcome and complications. Methods: Fifty consecutive eyes of 50 patients with PPRD were randomized into two groups, with 25 patients in ea ch of group 1 (scleral buckling group) and group 2 (pars plana vitrectomy withou t buckling group) in a hospital setting and followed up at 1 week, 2 weeks, 6 we eks and 6 months. Results: A primary reattachment rate of 76%(19 retinas) was o btained in group 1, while a reattachment rate of 84%(21 retinas) was achieved i n group 2. The final anatomic reattachment rate was 100%in both groups. The cau ses of failure in group 1were proliferative vitreoretinopathy in five eyes and o pen break/ missed break in one eye. The causes of failure in group 2 were missed break/op en break in three eyes and proliferative vitreoretinopathy in one eye. Best corr ected visual acuity (BCVA) at 2 weeks was better in group 1, while the final BCV A at end of 6 months was two lines better in group 2. The mean change in refract ive error was-1.38 D in group 1 and-0.85 D in group 2. Conclusions: Pars plana vitrectomywithout buckling provides an effective treatment for PPRD and results in better longterm visual and anatomic outcomes than conventional scleral buckl ing.展开更多
文摘Allogenic haematological stem cell transplantation (allo-SCT) from a human leukocyte antigen (HLA) matched related or unrelated donor is used as a curative therapy for a large number of malignant and non-malignant haematological diseases. The curative effect of allo-SCT is achieved by graft versus leukaemia effect while the downside of the graft versus patient activity is the graft-versus-host-disease (GVHD), a major reason for mortality and morbidity. The search of articles for this review had been accomplished using Ovid, Medline, Embase, Pubmed and was supplemented by retrieving cross references also. Electronic literature search for English language articles with full text access was performed using graft versus host disease, ocular, management, dry eyes as key words. This review has been intended to explicate the classification, pathogenesis, risk factors and management of ocular graft versus host disease.
文摘Cysticercosis is a preventable and eradicable cause of blindness endemic in the Indian subcontinent, South- East Asia and other developing countries. Ocular and orbital cysticercosis has varied presentations depending upon the site of involvement, number of lesion and the host immune response. In this article we present a review of the various clinical manifestations, diagnosis and management protocol for orbital and ocular cysticercosis. Owing to its varied presentation, cysticercosis may pose a diagnostic challenge to the health professionals. Early diagnosis and management can prevent the vision loss and optimize visual outcomes.
文摘Dear editor,Globe luxation is defined as complete prolapse of the eyeball outside the orbital cavity with eyelids closed behind the eyeball.Broadly,globe luxation can be categorized as traumatic,spontaneous or voluntary;males are affected more than females with an average age of 30 years.[1]Traumatic globe luxation is quite rare in children,with most cases reported in the adult age group.Orbital fracture comprises 5%to 25%of all facial fractures in the paediatric age group.[2]In cases with luxation of globe,immediate reposition is crucial for globe and vision salvage.We describe the clinical features,evaluation,and management of globe luxation present at birth following normal vaginal delivery conducted elsewhere.
文摘In patients with lagophthalmos due to eyelid trauma,it is imperative to ensure adequate closure of the eye to protect the ocular surface.Sometimes it is difficult to surgically close eyelids by conventional methods of tarsorrhaphy,such as intermarginal suture tarsorrhaphy,Week’s tarsorrhaphy,and tongue-in-groove tarsorrhaphy.We need intact eyelid tissues to perform these procedures and might not be possible in patients with severe lagophthalmos due to lost/damaged eyelid tissues either due to deficient length of tissues or increased tension at the wound site,which can result in surgical failure.[1]
文摘Purpose: To conduct a randomized prospective clinical trial to compare primary vitrectomy without scleral buckling versus conventional scleral buckling surger y in pseudophakic primary retinal detachment (PPRD) in terms of anatomic attachm ent rate, functional outcome and complications. Methods: Fifty consecutive eyes of 50 patients with PPRD were randomized into two groups, with 25 patients in ea ch of group 1 (scleral buckling group) and group 2 (pars plana vitrectomy withou t buckling group) in a hospital setting and followed up at 1 week, 2 weeks, 6 we eks and 6 months. Results: A primary reattachment rate of 76%(19 retinas) was o btained in group 1, while a reattachment rate of 84%(21 retinas) was achieved i n group 2. The final anatomic reattachment rate was 100%in both groups. The cau ses of failure in group 1were proliferative vitreoretinopathy in five eyes and o pen break/ missed break in one eye. The causes of failure in group 2 were missed break/op en break in three eyes and proliferative vitreoretinopathy in one eye. Best corr ected visual acuity (BCVA) at 2 weeks was better in group 1, while the final BCV A at end of 6 months was two lines better in group 2. The mean change in refract ive error was-1.38 D in group 1 and-0.85 D in group 2. Conclusions: Pars plana vitrectomywithout buckling provides an effective treatment for PPRD and results in better longterm visual and anatomic outcomes than conventional scleral buckl ing.
