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合并宫内感染的小孕周早产儿产程与大脑白质损伤的风险
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作者 Locatelli A. Vergani P. +2 位作者 Ghidini A. 王佳楣(译) 高雪莲(校) 《世界核心医学期刊文摘(妇产科学分册)》 2006年第1期9-10,共2页
The purpose of this study was to assess whether the duration of labor has any effect on the occurrence of cerebral white-matter damage in very preterm infants who are delivered in the presence of intrauterine infectio... The purpose of this study was to assess whether the duration of labor has any effect on the occurrence of cerebral white-matter damage in very preterm infants who are delivered in the presence of intrauterine infection. Study design: From a cohort of infants who were born spontaneously at < 32 weeks of gestation for whom placental information was available and who survived 7 days from birth, 126 infants had clinical, laboratory, or histologic evidence of intrauterine infection. Among them, variables were compared between those infants with white-matter damage (defined as intraventricular hemorrhage grade 3 plus, periventricular leukomalacia, or ventriculomegaly not associated with hydrocephaly [n = 13]) and those infants without it (n = 113). Comparisons were made with t test, chisquared test, and survival analysis; a probability value of < .05 was considered significant. Results: There were no differences between the 2 groups in gestational age at delivery and rates of labor or cesarean delivery. Duration of active labor (66 ± 45 minutes vs 88 ± 75 minutes; P = .49) and of clinical chorioamnionitis (310 ± 186 minutes vs 529 ± 544 minutes; P = .44) were similar in cases with and without neonatal white-matter damage. Conclusion: In 126 infants who were born at < 32 weeks of gestation with intrauterine infection, we found no correlation between the duration of labor or clinical chorioamnionitis and neonatal white-matter damage. 展开更多
关键词 脑白质损伤 宫内感染 产程长短 早产儿 小孕周 绒毛膜羊膜炎 脑室内出血 统计学分析 统计学差异 自然分娩率
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