The well-known frictional effect related to liquid-liquid two-phaseflow in pipelines can be reduced using drag-reducing additives.In this study,such an effect has been investigated experimentally using a mixture of oil...The well-known frictional effect related to liquid-liquid two-phaseflow in pipelines can be reduced using drag-reducing additives.In this study,such an effect has been investigated experimentally using a mixture of oil and water.Moreover,numerical simulations have been carried out using the COMSOL simulation software.The mea-surements were taken in a horizontal pipe with the length and diameter equal to 3 and 0.125 m,respectively.Moreover,Polyethylene oxide with 150 ppm was exploited to reduce the drag effect while considering different water-to-oil fractions(0.3,0.4,0.5,and 0.7)and a constant totalflow velocity of 2.3 m/s.As made evident by the results,a significant reduction can be obtained in terms of pressure drop,which becomes even more significant as the water to oil fraction is increased.The maximum achieved drag reduction is 70%with a water fraction of 0.7.The results also show that the addition of polymer additives can also have an impact on theflow pattern.Com-parison of experimental and numerically determined pressure drop indicates that the error is smaller than 7%.展开更多
BACKGROUND Spontaneous gastric hematoma is an exceedingly rare condition characterized by the accumulation of blood within the gastric wall without any apparent iatrogenic or traumatic cause.Coagulopathies are the mos...BACKGROUND Spontaneous gastric hematoma is an exceedingly rare condition characterized by the accumulation of blood within the gastric wall without any apparent iatrogenic or traumatic cause.Coagulopathies are the most frequent cause of gastric he-matomas.However,other causes include amyloidosis,pancreatitis,visceral vas-cular aneurysms,endoscopy complications and others.The pathophysiology of spontaneous gastric hematoma is not completely understood.However,it is postulated that it is caused by disruption of submucosal vessels that leads to dissection of the muscularis layer and formation of false lumen.The rarity of this condition increases the challenge of diagnosis,and there is no standard treatment protocol.CASE SUMMARY We present the case of a spontaneous gastric hematoma in a 22-year-old male.He presented to our emergency department complaining of pain in the left flank area lasting for 2 wk.There was no history of trauma,antico-agulant medications or endoscopy procedures.His hemoglobin and hematocrit levels were slightly lower than normal.Multi-slice computed tomography,ultrasound and endoscopy confirmed a gastric intramural hematoma.We recommended conservative treatment because there was no hemodynamic instability nor significant bleeding.The patient responded well,and there were no unexpected events.At the 3-mo follow-up,the ultrasound exa-mination revealed complete regression of the hematoma.CONCLUSION After reviewing the literature and our experience,we recommend that more of these cases should be treated conservatively.The tendency to treat these cases with potentially burdensome procedures such as total or subtotal gastrectomy should be significantly reduced.展开更多
In a high concentration substrate medium, a heterotrophic bacterium with high removal efficiency of ammonium, named W1, was isolated from activated sludge of coking wastewater treatment facility. The bacterium was Gra...In a high concentration substrate medium, a heterotrophic bacterium with high removal efficiency of ammonium, named W1, was isolated from activated sludge of coking wastewater treatment facility. The bacterium was Gram-negative, rod-shaped, and identified preliminarily as Alcaligenes sp. according to its morphological and physiological properties and its 16S rRNA gene sequence analysis. In the high concentration ammonium medium (400 mg·L 1 4 NH -N), the effects of C source, N source, C/N ratio and initial pH of medium on ammonium removal were investigated in order to determine the optimal condition for strain W1. The maximum ammonium removal was around 95% in 4 days in an improved medium. The production of N 2 gas was examined in a closed system that was full of pure oxygen at the beginning. N 2 gas was detected in the system after 4 days of cultivation, which further testified that strain W1 has heterotrophic nitrification and aerobic denitrification abilities simultaneously.展开更多
Chongqing is the largest municipality under the Chinese Central Government (MCG) in terms of administrative area and population and is now the most important economic and cultural center of the upper Yangtze River and...Chongqing is the largest municipality under the Chinese Central Government (MCG) in terms of administrative area and population and is now the most important economic and cultural center of the upper Yangtze River and Three Gorges area. The Three Gorges Dam project, one of the largest world infrastructure projects, causes a great deal of immigration to Chongqing and results in the rapid urbanization of the city, and it has brought in a great deal of environmental impact, which is a global concerned issue. This paper introduces the city profile of Chongqing municipality and its urbanization impact on energy and environment. The demand and the trend of energy consumption in built environment (building and transport) have been analysed. The living environment of Chongqing residents and the local energy efficient policy have been introduced. Finally the authors discuss the key issues of the sustainable urban development of Chongqing.展开更多
This paper proposed a two-tier location management mechanism (TTLM) by improving the current registration mechanism (CR) in IP Multimedia Subsystem (IMS). The TTLM includes the visited network registration and t...This paper proposed a two-tier location management mechanism (TTLM) by improving the current registration mechanism (CR) in IP Multimedia Subsystem (IMS). The TTLM includes the visited network registration and the home network registration, in which the visited network registration is responsible for re-registration in IMS. When subscriber roams, the location information of home network will be updated by the visited network based on the change of user equipment (UE)' s IP address. Thereibre the TTLM can reduce the times of IMS registration signaling. Using the proposed analytical model, the performance of the CR and the proposed TTLM were investigated. After the performance analysis of CR and TTLM by using proposed analytical model, the cost of CR in IMS could significantly be reduced theoretically and also was proven by simulation experiments.展开更多
BACKGROUND Type 2 diabetes mellitus(T2DM)has high morbidity and mortality worldwide,therefore there is of paramount importance to identify the risk factors in the populations at risk early in the course of illness.A s...BACKGROUND Type 2 diabetes mellitus(T2DM)has high morbidity and mortality worldwide,therefore there is of paramount importance to identify the risk factors in the populations at risk early in the course of illness.A strong correlation between severity of metabolic syndrome(MetS)and HbA1c,fasting insulin and insulin resistance has been reported.Accordingly,the MetS severity score(or MestS Zscore)can potentially be used to predict the risk of T2DM progression over time.AIM To evaluate the association the of MestS Z-score in first degree relatives(FDRs)of T2DM with the risk of prediabetes and type 2 diabetes in future.METHODS A prospective open cohort study was conducted between 2003-2018.At baseline,the sample comprised of 1766 FDRs of patients with T2DM who had a normal glucose tolerance test.Relative risk(RR)and 95%confidence interval were calculated based on logistic regression.The receiver-operator characteristic analysis and area under the curve based on MetS Z-score were used to evaluate the risk of prediabetes and diabetes among the FDR population.RESULTS Baseline MetS Z-scores were associated with the its latest values(P<0.0001).Compared with individuals who were T2DM free at the end of follow up,those who developed T2DM had higher MetS Z-score at baseline(P<0.001).In multivariable logistic regression analyses for every unit elevation in MetS Z-score at the baseline,the RR for developing future T2DM and prediabetes was(RR=1.94,RR=3.84),(RR=1.5,RR=2.17)in total population and female group,respectively(P<0.05).The associations remained significant after adjusting the potential confounding variables.A cut off value of 0.97 and 0.94 was defined in the receiver-operator characteristic curve based on the MetS Z-score for differentiating female patients with diabetes and prediabetes from the normal population,respectively.CONCLUSION The MetS Z-score was associated with an increased risk of future T2DM.Appropriate interventions at earlier stages for preventing and attenuating MetS effects may be considered as an effective strategy for FDR as at-risk population.展开更多
The present study compared eight breeds of cattle differing in gender (heifers, buls and steers) to determine associations between muscle characteristics and meat sensory qualities of theLongissimus thoracis muscle....The present study compared eight breeds of cattle differing in gender (heifers, buls and steers) to determine associations between muscle characteristics and meat sensory qualities of theLongissimus thoracis muscle. Animal types differed in al the muscle characteristics and sensory qualities. Many correlations among muscle characteristics and among sensory qualities were consistent for most animal types. Isocitrate dehydrogenase (ICDH) activities alowed discrimination of muscles with respect to myosin heavy chain (MyHC)-I proportions for al animal types. Lactate dehydrogenase (LDH) and phos-phofructokinase (PFK) activities were positively correlated for most animal types. Overal liking was correlated with beef lfavour and abnormal lfavour in al animal types and with global tenderness for al animal types except for Charolais cross breed steers. For al animal types except for Angus×Friesian heifers, beef lfavour and abnormal lfavour were negatively correlated. Overal liking was not correlated with juiciness. PFK, ICDH and citrate synthase (CS) activities were strongly associated with tenderness, beef lfavour and overal liking when average values for al animal types were used. However, associations between muscle characteristics and sensory qualities within animal types were weak and inconsistent.展开更多
The Declarative/Procedural Model of Pinker, Ullman and colleagues claims that the basal ganglia are part of a fronto-striatal procedural memory system which applies grammatical rules to combine morphemes (the smallest...The Declarative/Procedural Model of Pinker, Ullman and colleagues claims that the basal ganglia are part of a fronto-striatal procedural memory system which applies grammatical rules to combine morphemes (the smallest meaningful units in language) into complex words (e.g. talk-ed, talk-ing). We tested this claim b y investigating whether striatal damage or loss of its dopaminergic innervation is reliably associated with selective regular past tense deficits in patients wi th subcortical cerebrovascular damage, Parkinson’s disease or Huntington’s dis ease.We focused on past tense morphology since this allows us to contrast the re gular past tense (jump-jumped), which is rulebased,with the irregular past tens e (sleep-slept), which is not We used elicitation and priming tasks to test pat ients’ability to comprehend and produce inflected forms. We found no evidence o f a consistent association between striatal dysfunction and selective impairment of regular past tensemorphology, suggesting that the basal ganglia are not esse ntial for processing the regular past tense as a sequence of morphemes, either i n comprehension or production, in contrast to the claims of the Declarative/Proc edural Model. All patient groups showed normal activation of semantic and morpho logical representations in comprehension, despite difficulties suppressing seman tically appropriate alternatives when trying to inflect novel verbs. This is con sistent with previous reports that striatal dysfunction spares automatic activat ion of linguistic information, but disrupts later language processes that requir e inhibition of competing alternatives.展开更多
This paper introduces the interrelationships between urban form, microclimate and thermal comfort. It draws on recent research of monitoring, surveying and modelling urban thermal characteristics and proposes a method...This paper introduces the interrelationships between urban form, microclimate and thermal comfort. It draws on recent research of monitoring, surveying and modelling urban thermal characteristics and proposes a method of mapping urban diversity. Because the urban context provides a rich and varied environment that influences the way we use urban spaces (movement, sequence, activity) and how we feel in them (stimulation, thermal comfort), the aim here is to highlight the notion of diversity. Thus thermal diversity is used as a measure of the urban environment, rather than more conventional spatially or temporally fixed average values.展开更多
The Epstein-Barr virus membrane antigen was constructed and inserted into vaccinia virus, Tian-tan strain in order to study the effect of this virus on EB infection and tumorogenesis. The EBV-derived membrane antigen ...The Epstein-Barr virus membrane antigen was constructed and inserted into vaccinia virus, Tian-tan strain in order to study the effect of this virus on EB infection and tumorogenesis. The EBV-derived membrane antigen was expressed under the control of a 7.5 K promoter of vaccinia virus. The antibody against the membrane antigen of EB virus was produced on rabbits vaccinated with recombinant vaccinia virus.展开更多
文摘The well-known frictional effect related to liquid-liquid two-phaseflow in pipelines can be reduced using drag-reducing additives.In this study,such an effect has been investigated experimentally using a mixture of oil and water.Moreover,numerical simulations have been carried out using the COMSOL simulation software.The mea-surements were taken in a horizontal pipe with the length and diameter equal to 3 and 0.125 m,respectively.Moreover,Polyethylene oxide with 150 ppm was exploited to reduce the drag effect while considering different water-to-oil fractions(0.3,0.4,0.5,and 0.7)and a constant totalflow velocity of 2.3 m/s.As made evident by the results,a significant reduction can be obtained in terms of pressure drop,which becomes even more significant as the water to oil fraction is increased.The maximum achieved drag reduction is 70%with a water fraction of 0.7.The results also show that the addition of polymer additives can also have an impact on theflow pattern.Com-parison of experimental and numerically determined pressure drop indicates that the error is smaller than 7%.
文摘BACKGROUND Spontaneous gastric hematoma is an exceedingly rare condition characterized by the accumulation of blood within the gastric wall without any apparent iatrogenic or traumatic cause.Coagulopathies are the most frequent cause of gastric he-matomas.However,other causes include amyloidosis,pancreatitis,visceral vas-cular aneurysms,endoscopy complications and others.The pathophysiology of spontaneous gastric hematoma is not completely understood.However,it is postulated that it is caused by disruption of submucosal vessels that leads to dissection of the muscularis layer and formation of false lumen.The rarity of this condition increases the challenge of diagnosis,and there is no standard treatment protocol.CASE SUMMARY We present the case of a spontaneous gastric hematoma in a 22-year-old male.He presented to our emergency department complaining of pain in the left flank area lasting for 2 wk.There was no history of trauma,antico-agulant medications or endoscopy procedures.His hemoglobin and hematocrit levels were slightly lower than normal.Multi-slice computed tomography,ultrasound and endoscopy confirmed a gastric intramural hematoma.We recommended conservative treatment because there was no hemodynamic instability nor significant bleeding.The patient responded well,and there were no unexpected events.At the 3-mo follow-up,the ultrasound exa-mination revealed complete regression of the hematoma.CONCLUSION After reviewing the literature and our experience,we recommend that more of these cases should be treated conservatively.The tendency to treat these cases with potentially burdensome procedures such as total or subtotal gastrectomy should be significantly reduced.
基金Supported by the National Natural Science Foundation of China (51078252)the International Cooperation Projects of Shanxi Province (2010081018)the Natural Science Foundation of Shanxi Province (2010011016-1)
文摘In a high concentration substrate medium, a heterotrophic bacterium with high removal efficiency of ammonium, named W1, was isolated from activated sludge of coking wastewater treatment facility. The bacterium was Gram-negative, rod-shaped, and identified preliminarily as Alcaligenes sp. according to its morphological and physiological properties and its 16S rRNA gene sequence analysis. In the high concentration ammonium medium (400 mg·L 1 4 NH -N), the effects of C source, N source, C/N ratio and initial pH of medium on ammonium removal were investigated in order to determine the optimal condition for strain W1. The maximum ammonium removal was around 95% in 4 days in an improved medium. The production of N 2 gas was examined in a closed system that was full of pure oxygen at the beginning. N 2 gas was detected in the system after 4 days of cultivation, which further testified that strain W1 has heterotrophic nitrification and aerobic denitrification abilities simultaneously.
基金UK FCO GOF(PGI GCC 000012) and Chongqing Small town Programme (CSTC-2004AA7008)
文摘Chongqing is the largest municipality under the Chinese Central Government (MCG) in terms of administrative area and population and is now the most important economic and cultural center of the upper Yangtze River and Three Gorges area. The Three Gorges Dam project, one of the largest world infrastructure projects, causes a great deal of immigration to Chongqing and results in the rapid urbanization of the city, and it has brought in a great deal of environmental impact, which is a global concerned issue. This paper introduces the city profile of Chongqing municipality and its urbanization impact on energy and environment. The demand and the trend of energy consumption in built environment (building and transport) have been analysed. The living environment of Chongqing residents and the local energy efficient policy have been introduced. Finally the authors discuss the key issues of the sustainable urban development of Chongqing.
基金Supported by National Science Fund for Distinguished Young Scholars (No. 60525110 )National Basic Research Program of China (No.2007CB307100, 2007CB307103)+1 种基金Program for New Century Excellent Talents in University (No. NCET-04-0111 )Development Fund Project for Electronic and Information Industry (Mobile Service and Application System Based on 3G)
文摘This paper proposed a two-tier location management mechanism (TTLM) by improving the current registration mechanism (CR) in IP Multimedia Subsystem (IMS). The TTLM includes the visited network registration and the home network registration, in which the visited network registration is responsible for re-registration in IMS. When subscriber roams, the location information of home network will be updated by the visited network based on the change of user equipment (UE)' s IP address. Thereibre the TTLM can reduce the times of IMS registration signaling. Using the proposed analytical model, the performance of the CR and the proposed TTLM were investigated. After the performance analysis of CR and TTLM by using proposed analytical model, the cost of CR in IMS could significantly be reduced theoretically and also was proven by simulation experiments.
基金Supported by Isfahan Endocrine and Metabolism Research Center,No. 95017.
文摘BACKGROUND Type 2 diabetes mellitus(T2DM)has high morbidity and mortality worldwide,therefore there is of paramount importance to identify the risk factors in the populations at risk early in the course of illness.A strong correlation between severity of metabolic syndrome(MetS)and HbA1c,fasting insulin and insulin resistance has been reported.Accordingly,the MetS severity score(or MestS Zscore)can potentially be used to predict the risk of T2DM progression over time.AIM To evaluate the association the of MestS Z-score in first degree relatives(FDRs)of T2DM with the risk of prediabetes and type 2 diabetes in future.METHODS A prospective open cohort study was conducted between 2003-2018.At baseline,the sample comprised of 1766 FDRs of patients with T2DM who had a normal glucose tolerance test.Relative risk(RR)and 95%confidence interval were calculated based on logistic regression.The receiver-operator characteristic analysis and area under the curve based on MetS Z-score were used to evaluate the risk of prediabetes and diabetes among the FDR population.RESULTS Baseline MetS Z-scores were associated with the its latest values(P<0.0001).Compared with individuals who were T2DM free at the end of follow up,those who developed T2DM had higher MetS Z-score at baseline(P<0.001).In multivariable logistic regression analyses for every unit elevation in MetS Z-score at the baseline,the RR for developing future T2DM and prediabetes was(RR=1.94,RR=3.84),(RR=1.5,RR=2.17)in total population and female group,respectively(P<0.05).The associations remained significant after adjusting the potential confounding variables.A cut off value of 0.97 and 0.94 was defined in the receiver-operator characteristic curve based on the MetS Z-score for differentiating female patients with diabetes and prediabetes from the normal population,respectively.CONCLUSION The MetS Z-score was associated with an increased risk of future T2DM.Appropriate interventions at earlier stages for preventing and attenuating MetS effects may be considered as an effective strategy for FDR as at-risk population.
基金the framework of the EU Project ProSafeBeef(FOOD-CT-2006-36241)with INRA(Institut National de la Recherche Agronomique,France)Quality Assurance number AQ284
文摘The present study compared eight breeds of cattle differing in gender (heifers, buls and steers) to determine associations between muscle characteristics and meat sensory qualities of theLongissimus thoracis muscle. Animal types differed in al the muscle characteristics and sensory qualities. Many correlations among muscle characteristics and among sensory qualities were consistent for most animal types. Isocitrate dehydrogenase (ICDH) activities alowed discrimination of muscles with respect to myosin heavy chain (MyHC)-I proportions for al animal types. Lactate dehydrogenase (LDH) and phos-phofructokinase (PFK) activities were positively correlated for most animal types. Overal liking was correlated with beef lfavour and abnormal lfavour in al animal types and with global tenderness for al animal types except for Charolais cross breed steers. For al animal types except for Angus×Friesian heifers, beef lfavour and abnormal lfavour were negatively correlated. Overal liking was not correlated with juiciness. PFK, ICDH and citrate synthase (CS) activities were strongly associated with tenderness, beef lfavour and overal liking when average values for al animal types were used. However, associations between muscle characteristics and sensory qualities within animal types were weak and inconsistent.
文摘The Declarative/Procedural Model of Pinker, Ullman and colleagues claims that the basal ganglia are part of a fronto-striatal procedural memory system which applies grammatical rules to combine morphemes (the smallest meaningful units in language) into complex words (e.g. talk-ed, talk-ing). We tested this claim b y investigating whether striatal damage or loss of its dopaminergic innervation is reliably associated with selective regular past tense deficits in patients wi th subcortical cerebrovascular damage, Parkinson’s disease or Huntington’s dis ease.We focused on past tense morphology since this allows us to contrast the re gular past tense (jump-jumped), which is rulebased,with the irregular past tens e (sleep-slept), which is not We used elicitation and priming tasks to test pat ients’ability to comprehend and produce inflected forms. We found no evidence o f a consistent association between striatal dysfunction and selective impairment of regular past tensemorphology, suggesting that the basal ganglia are not esse ntial for processing the regular past tense as a sequence of morphemes, either i n comprehension or production, in contrast to the claims of the Declarative/Proc edural Model. All patient groups showed normal activation of semantic and morpho logical representations in comprehension, despite difficulties suppressing seman tically appropriate alternatives when trying to inflect novel verbs. This is con sistent with previous reports that striatal dysfunction spares automatic activat ion of linguistic information, but disrupts later language processes that requir e inhibition of competing alternatives.
文摘This paper introduces the interrelationships between urban form, microclimate and thermal comfort. It draws on recent research of monitoring, surveying and modelling urban thermal characteristics and proposes a method of mapping urban diversity. Because the urban context provides a rich and varied environment that influences the way we use urban spaces (movement, sequence, activity) and how we feel in them (stimulation, thermal comfort), the aim here is to highlight the notion of diversity. Thus thermal diversity is used as a measure of the urban environment, rather than more conventional spatially or temporally fixed average values.
文摘The Epstein-Barr virus membrane antigen was constructed and inserted into vaccinia virus, Tian-tan strain in order to study the effect of this virus on EB infection and tumorogenesis. The EBV-derived membrane antigen was expressed under the control of a 7.5 K promoter of vaccinia virus. The antibody against the membrane antigen of EB virus was produced on rabbits vaccinated with recombinant vaccinia virus.