Artificial intelligence for characterization of diminutive colorectal polyps:A feasibility study comparing two computer-aided diagnosis systems

BACKGROUND Artificial intelligence(AI)has potential in the optical diagnosis of colorectal polyps.AIM To evaluate the feasibility of the real-time use of the computer-aided diagnosis system(CADx)AI for ColoRectal Polyps(AI4CRP)for the optical diagnosis of diminutive colorectal polyps and to compare the performance with CAD EYE^(TM)(Fujifilm,Tokyo,Japan).CADx influence on the optical diagnosis of an expert endoscopist was also investigated.METHODS AI4CRP was developed in-house and CAD EYE was proprietary software provided by Fujifilm.Both CADxsystems exploit convolutional neural networks.Colorectal polyps were characterized as benign or premalignant and histopathology was used as gold standard.AI4CRP provided an objective assessment of its characterization by presenting a calibrated confidence characterization value(range 0.0-1.0).A predefined cut-off value of 0.6 was set with values<0.6 indicating benign and values≥0.6 indicating premalignant colorectal polyps.Low confidence characterizations were defined as values 40%around the cut-off value of 0.6(<0.36 and>0.76).Self-critical AI4CRP’s diagnostic performances excluded low confidence characterizations.RESULTS AI4CRP use was feasible and performed on 30 patients with 51 colorectal polyps.Self-critical AI4CRP,excluding 14 low confidence characterizations[27.5%(14/51)],had a diagnostic accuracy of 89.2%,sensitivity of 89.7%,and specificity of 87.5%,which was higher compared to AI4CRP.CAD EYE had a 83.7%diagnostic accuracy,74.2%sensitivity,and 100.0%specificity.Diagnostic performances of the endoscopist alone(before AI)increased nonsignificantly after reviewing the CADx characterizations of both AI4CRP and CAD EYE(AI-assisted endoscopist).Diagnostic performances of the AI-assisted endoscopist were higher compared to both CADx-systems,except for specificity for which CAD EYE performed best.CONCLUSION Real-time use of AI4CRP was feasible.Objective confidence values provided by a CADx is novel and self-critical AI4CRP showed higher diagnostic performances compared to AI4CRP.

Electron beam pumping improves the conversion efficiency of low-frequency photons radiated by perovskite quantum dots

This research argues that using an electron beam with high kinetic energy to pump perovskite quantum dots can significantly boost the efficiency of the low-frequency photon radiation conversion.Firstly,we measure the random lasing threshold and luminescence threshold of CsPbX_(3)films pumped by an electron beam.Then,we simulate the spatial distribution of the electron beams in CsPbX_(3)films.Combined with the above data,a low-frequency photon radiation conversion model based on the electron pumped perovskite quantum dots is presented.This could be a way to create a terahertz source with a high-power output or to multiply the terahertz power.

Meta-analysis of CO_(2) conversion,energy efficiency,and other performance data of plasma-catalysis reactors with the open access PIONEER database

This paper brings the comparison of performances of CO_(2)conversion by plasma and plasma-assisted catalysis based on the data collected from literature in this field,organised in an open access online database.This tool is open to all users to carry out their own analyses,but also to contributors who wish to add their data to the database in order to improve the relevance of the comparisons made,and ultimately to improve the efficiency of CO_(2)conversion by plasma-catalysis.The creation of this database and database user interface is motivated by the fact that plasma-catalysis is a fast-growing field for all CO_(2)conversion processes,be it methanation,dry reforming of methane,methanolisation,or others.As a result of this rapid increase,there is a need for a set of standard procedures to rigorously compare performances of different systems.However,this is currently not possible because the fundamental mechanisms of plasma-catalysis are still too poorly understood to define these standard procedures.Fortunately however,the accumulated data within the CO_(2)plasma-catalysis community has become large enough to warrant so-called“big data”studies more familiar in the fields of medicine and the social sciences.To enable comparisons between multiple data sets and make future research more effective,this work proposes the first database on CO_(2)conversion performances by plasma-catalysis open to the whole community.This database has been initiated in the framework of a H_(2)0_(2)0 European project and is called the“PIONEER Data Base”.The database gathers a large amount of CO_(2)conversion performance data such as conversion rate,energy efficiency,and selectivity for numerous plasma sources coupled with or without a catalyst.Each data set is associated with metadata describing the gas mixture,the plasma source,the nature of the catalyst,and the form of coupling with the plasma.Beyond the database itself,a data extraction tool with direct visualisation features or advanced filtering functionalities has been developed and is available online to the public.The simple and fast visualisation of the state of the art puts new results into context,identifies literal gaps in data,and consequently points towards promising research routes.More advanced data extraction illustrates the impact that the database can have in the understanding of plasma-catalyst coupling.Lessons learned from the review of a large amount of literature during the setup of the database lead to best practice advice to increase comparability between future CO_(2)plasma-catalytic studies.Finally,the community is strongly encouraged to contribute to the database not only to increase the visibility of their data but also the relevance of the comparisons allowed by this tool.

Enhanced Hoek-Brown(H-B)criterion for rocks exposed to chemical corrosion

Underground constructions often encounter water environments,where water–rock interaction can increase porosity,thereby weakening engineering rocks.Correspondingly,the failure criterion for chemically corroded rocks becomes essential in the stability analysis and design of such structures.This study enhances the applicability of the Hoek-Brown(H-B)criterion for engineering structures operating in chemically corrosive conditions by introducing a kinetic porosity-dependent instantaneous mi(KPIM).A multiscale experimental investigation,including nuclear magnetic resonance(NMR),X-ray diffraction(XRD),scanning electron microscopy(SEM),pH and ion chromatography analysis,and triaxial compression tests,is employed to quantify pore structural changes and their linkage with the strength responses of limestone under coupled chemical-mechanical(C-M)conditions.By employing ion chromatography and NMR analysis,along with incorporating the principles of free-face dissolution theory accounting for both congruent and incongruent dissolution,a kinetic chemical corrosion model is developed.This model aims to calculate the kinetic porosity alterations within rocks exposed to varying H+concentrations and durations.Subsequently,utilizing the generalized mixture rule(GMR),the kinetic porositydependent mi is formulated.Evaluation of the KPIM-enhanced H-B criterion using compression test data from 5 types of rocks demonstrated a high level of consistency between the criterion and the experimental results,with a coefficient of determination greater than 0.96,a mean absolute percentage error less than 4.84%,and a root-mean-square deviation less than 5.95 MPa.Finally,the physical significance of the porosity-dependent instantaneous mi is clarified:it serves as an indicator of a rock’s capacity to leverage the confining pressure effect.

Study on green power supply modes for heavy load in Remote Areas

In this study,the present situation and characteristics of power supply in remote areas are summarized.By studying the cases of power supply projects in remote areas,the experience is analyzed and described,and the applicability of related technologies,such as grid-forming storage and power load management,is studied,including grid-connection technologies,such as grid-forming converters and power load management.On this basis,three power-supply modes were proposed.The application scenarios and advantages of the three modes were compared and analyzed.Based on the local development situation,the temporal sequences of the three schemes are described,and a case study was conducted.The study of the heavy-load power supply mode in remote areas contributes to solving the problem of heavy-load green power consumption in remote areas and promoting the further development of renewable energy.

Influence of the embedded structure on the EFP formation of compact terminal sensitive projectile

To improve the damage efficiency of compact terminal sensitive projectile with EFP warhead,it is vital to understand how the embedded structure(ES)affects the EFP forming performance.In this paper,the corresponding numerical investigation is focused on,in which the fluid-structure interaction(FSI)method and the experimental verification are used.Based on the obtained quantitative relations between the forming performance and a(the ratio of height to maximum radius of ES),an optimal design is further provided.The results indicate that:when the embedded structural length and width range 0.1e0.3D and 0.1e0.2D(D:diameter of EFP warhead)at a fixed volume,respectively,EFP forming velocity nearly keeps as a constant,1760 m/s;the height of ES has a dramatical effect on the propagating range of detonation wave,resulting in significant influence on the aerodynamic shape and length-to-diameter ratio of EFP;under the given constraints,the EFP length-diameter ratio can reach the optimal value2.76,when the height of ES is 0.22D.

Analysis of Metro Station Ridership Considering Spatial Heterogeneity

This study aims to explore the role of spatial heterogeneity in ridership analysis and examine the relationship between built environment, station attributes and urban rapid transit ridership at the station level.Although spatial heterogeneity has been widely acknowledged in spatial data analysis, it has been rarely considered in travel behavior studies.Four models(three global models-ordinary least squares(OLS), spatial lag model(SLM), spatial error model(SEM) and one local model-geographically weighted regression(GWR) model) are estimated separately to explore the relationship between various independent variables and station ridership, and identify the influence of spatial heterogeneity.Using the data of built environment and station characteristics, the results of diagnostic identify evidence the existence of spatial heterogeneity in station ridership for the metro network in Nanjing, China.Results of comparing the various goodness-of-fit indicators show that, the GWR model yields the best fit of the data, performance followed by the SEM, SLM and OLS model.The results also demonstrate that population, number of lines, number of feeder buses, number of exits, road density and proportion residential area have a significant impact on station ridership.Moreover, the study pays special attention to the spatial variation in the coefficients of the independent variables and their statistical significance.It underlines the importance of taking spatial heterogeneity into account in the station ridership analysis and the decision-making in urban planning.

An electrophoretic display driving waveform based on improvement of activation pattern

Electrophoretic display(EPD) technology has become one of the main supporting pillars of the electronic paper display industry.Despite its benefits,the EPD technology suffers from several disadvantages such as non-fixed threshold voltage value for gray scale display.In addition,the display has to repeatedly refresh between white and black states to eliminate ghost image when it needs to update a new image.The traditional driving waveform for the EPD includes four stages: erasing the original image,resetting to black state,clearing to white state,and writing a new image.A flicker can be found when transferring between two adjacent stages.A new driving waveform based on the improvement of activation pattern is proposed to weaken the ghost image and reduce the flicker.Experimental results show that the proposed driving waveform could weaken the ghost image effectively and reduce the number of flickers by 50%.Compared with the traditional driving waveform,the driving waveform of this work has a better performance.

Convergence Properties of Local Defect Correction Algorithm for the Boundary Element Method

Sometimes boundary value problems have isolated regions where the solution changes rapidly.Therefore,when solving numerically,one needs a fine grid to capture the high activity.The fine grid can be implemented as a composite coarse-fine grid or as a global fine grid.One cheaper way of obtaining the composite grid solution is the use of the local defect correction technique.The technique is an algorithm that combines a global coarse grid solution and a local fine grid solution in an iterative way to estimate the solution on the corresponding composite grid.The algorithm is relatively new and its convergence properties have not been studied for the boundary element method.In this paper the objective is to determine convergence properties of the algorithm for the boundary element method.First,we formulate the algorithm as a fixed point iterative scheme,which has also not been done before for the boundary element method,and then study the properties of the iteration matrix.Results show that we can always expect convergence.Therefore,the algorithm opens up a real alternative for application in the boundary element method for problems with localised regions of high activity.

CONTROLLING THE 3D NANOSCALE ORGANIZATION OF BULK HETEROJUNCTION POLYMER SOLAR CELLS

In this study,the three dimensional nanoscale organization in the photoactive layers of poly(3-hexylthiophene) (P3HT) and a methanofullerene derivative (PCBM) is revealed by transmission electron tomography.After annealing treatment,either at elevated temperature or during slow solvent evaporation,nanoscale interpenetrating networks are formed with high crystalline order and favorable concentration gradients of both components through the thickness of the photoactive layer.Such a tailored morphology account...

Exponential Set-Point Stabilization of Underactuated Vehicles Moving in Three-Dimensional Space

This paper investigates the stabilization of underactuated vehicles moving in a three-dimensional vector space.The vehicle’s model is established on the matrix Lie group SE(3),which describes the configuration of rigid bodies globally and uniquely.We focus on the kinematic model of the underactuated vehicle,which features an underactuation form that has no sway and heave velocity.To compensate for the lack of these two velocities,we construct additional rotation matrices to generate a motion of rotation coupled with translation.Then,the state feedback is designed with the help of the logarithmic map,and we prove that the proposed control law can exponentially stabilize the underactuated vehicle to the identity group element with an almost global domain of attraction.Later,the presented control strategy is extended to set-point stabilization in the sense that the underactuated vehicle can be stabilized to an arbitrary desired configuration specified in advance.Finally,simulation examples are provided to verify the effectiveness of the stabilization controller.

Experimental study on attenuation of Stoneley wave under different fracture factors

To quantitatively determine the effect of different factors such as fracture width,dip angle,extension and filling material on Stoneley wave amplitude decreasing,the shock tube experiment method was changed from fixing the sample and vertically moving the sensor in the borehole to fixing the sensors along the shock tube wall and vertically moving the sample without drilling the borehole in it.The measurement accuracy and the signal-to-noise ratio of the first Stoneley wave were improved by the time corrections and amplitude corrections of Stoneley wave signals.At the same time,21 sets of core models with different fracture parameters were processed for this measurement method by using full-diameter carbonate core,and relative amplitudes were defined to characterize Stoneley wave amplitude decreasing.The experimental results show that the relative amplitude of Stoneley wave exponentially decreases with increasing fracture width.The relative amplitude of Stoneley wave linearly decreases with increasing fracture dip angle.The relative amplitude of Stoneley wave exponentially decreases with increasing fracture extension.The relative amplitude of Stoneley wave decreases with increasing the permeability of filling material in the fracture.Under the above four conditions,the fracture width has the greatest effect on the decreasing of Stoneley wave amplitude,followed by the fracture extension and the permeability of filling material,and finally the fracture dip angle.

A New Model to Study Healing of a Complex Femur Fracture with Concurrent Soft Tissue Injury in Sheep

High energy bone fractures resulting from impact trauma are often accompanied by subcutaneous soft tissue injuries, even if the skin remains intact. There is evidence that such closed soft tissue injuries affect the healing of bone fractures, and vice versa. Despite this knowledge, most impact trauma studies in animals have focussed on bone fractures or soft tissue trauma in isolation. However, given the simultaneous impact on both tissues a better understanding of the interaction between these two injuries is necessary to optimise clinical treatment. The aim of this study was therefore to develop a new experimental model and characterise, for the first time, the healing of a complex fracture with concurrent closed soft tissue trauma in sheep. A pendulum impact device was designed to deliver a defined and standardised impact to the distal thigh of sheep, causing a reproducible contusion injury to the subcutaneous soft tissues. In a subsequent procedure, a reproducible femoral butterfly fracture (AO C3-type) was created at the sheep’s femur, which was initially stabilised for 5 days by an external fixator construct to allow for soft tissue swelling to recede, and ultimately in a bridging construct using locking plates. The combined injuries were applied to twelve sheep and the healing observed for four or eight weeks (six animals per group) until sacrifice. The pendulum impact led to a moderate to severe circumferential soft tissue injury with significant bruising, haematomas and partial muscle disruptions. Posttraumatic measurements showed elevated intra-compartmental pressure and circulatory tissue breakdown markers, with recovery to normal, pre-injury values within four days. Clinically, no neurovascular deficiencies were observed. Bi-weekly radiological analysis of the healing fractures showed progressive callus healing over time, with the average number of callus bridges increasing from 0.4 at two weeks to 4.2 at eight weeks. Biomechanical testing after sacrifice showed in- creasing torsional stiffness between four and eight weeks healing time from 10% to 100%, and increasing ultimate torsional strength from 10% to 64% (relative to the contralateral control limb). Our results demonstrate the robust healing of a complex femur fracture in the presence of a severe soft tissue contusion injury in sheep and demonstrate the establishment of a clinically relevant experimental model, for research aimed at improving the treatment of bone fractures accompanied by closed soft tissue injuries.

Synthesis of a Green Nano-Silica Material Using Beneficiated Waste Dunites and Its Application in Concrete

Nano-silica, one of the substances boosting the field of nanomaterials, can be produced by dissolving olivine in acid. The dissolution of olivine is a convenient alternative route to the existing methods of nano-silica production (neutralization of sodium silicate and flame hydrolysis) because the olivine dissolution is a low temperature process making this method cheaper and greener. Furthermore, this process can use waste olivine materials for the production of nano-silica. The produced nano-silica has a specific surface area between 100 and 400 m2/g;a primary particle size between 10 and 25 nm, which is agglomerated in clusters;and an impurity content below 5 wt.%. In addition, olivine nano-silica can be classified as a pozzolanic material with an activity index of 101%. The optimum replacement level of olivine nano-silica in conventional vibrated concrete is around 5% by volume resulting in: 1) a compressive strength increase of 20%;2) a CO2 emission reduction of 3%. Therefore, the use of the olivine nano-silica in CVC does not only improve the compressive strength but also reduce the CO2 emissions.

Verification of Hypertorus Communication Grids by Infinite Petri Nets and Process Algebra

A model of a hypertorus communication grid has been constructed in the form of an infinite Petri net. A grid cell represents either a packet switching device or a bioplast cell. A parametric expression is obtained to allow a finite specification of an infinite Petri net. To prove properties of an ideal communication protocol, we derive an infinite Diophantine system of equations from it, which is subsequently solved. Then we present the programs htgen and ht-mcrl2-gen, developed in the C language, which generate Petri net and process algebra models of a hypertorus with a given number of dimensions and grid size. These are the inputs for the respective modeling tools Tina and mCRL2, which provide model visualization, step simulation, state space generation and reduction, and structural analysis techniques. Benchmarks to compare the two approaches are obtained. An ad-hoc induction-like technique on invariants,obtained for a series of generated models, allows the calculation of a solution of the Diophantine system in a parametric form.It is proven that the basic solutions of the infinite system have been found and that the infinite Petri net is bounded and conservative. Some remarks regarding liveness and liveness enforcing techniques are also presented.

A 60 GHz Phased Array System Analysis and Its Phase Shifter in a 40 nm CMOS Technology

A 60 GHz phased array system for mm wave frequency in 5G is introduced and a 5 bit digitally controlled phase shifter in 40 nm CMOS technology is presented.In a phased array system,the signal to noise ratio(SNR)of the receiver is improved with the beaming forming function.Therefore,the communication data rate and distance are improved accordingly.The phase shifter is the key component for achieving the beam forming function,and its resolution and power consumption are also very critical.In the second half of this paper,an analysis of phase shifter is introduced,and a 60 GHz 5 bit digitally controlled phase shifter in 40 nm complementary metal oxide semiconductor(CMOS)technology is presented.In this presented phase shifter,a hybrid structure is implemented for its advantage on lower phase deviation while keeping comparable loss.Meanwhile,this digitally controlled phase shifter is much more compact than other works.For all 32 states,the minimum phase error is 1.5°,and the maximum phase error is 6.8°.The measured insertion loss is-20.9±1 dB including pad loss at 60 GHz and the return loss is more than 10 dB over 57-64 GHz.The total chip size is 0.24 mm^2 with 0 mW DC power consumption.

MISCIBILITY BEHAVIOR AND PRESSURE DEPENDENCE OF THE SYSTEMS POLYSTYRENE/CYCLOPENTANE AND POLYSTYRENE/1-PHENYLDECANE ACCORDING TO A MODIFIED HOLE THEORY

The influence of pressure on miscibility behavior of the systems polystyrene/cyclopentan(?)and polystyrene/1-phenyldecane is studied with a modified hole theory.It is found that the pres-sure dependence of excess volume is responsible for the different kinds of behavior of these two sys-tems.Furthermore,the excess volume is decomposed into two separatc parts,one from the contri-bution of cell volume expansion and the other from the change of hole fraction,and their relation-ship with pressure dependence of the miscibility behavior is analysed.

The role of solvents in the formation of methylammonium lead triiodide perovskite

Metal halide perovskites(MHPs) are gaining increasing attention as low-cost, high-performance semiconductors for optoelectronics. In particular, their solution processing is compatible with the largescale manufacturing of thin-film devices, including solar cells and light-emitting diodes.Understanding the coordination chemistry in precursor-solvent solution and atomistic mechanisms of film formation is of great importance for optimizing the optoelectronic properties of the final films.Using the methylammonium lead triiodide(MAPbI_(3)) as an example, we study the complex evolution of the molecular species from the solution to the initial stage of the crystallization by using a combination of density functional theory(DFT) calculations and ab-initio molecular dynamics(AIMD) simulations. We focus on the widely employed solvents DMSO and DMF, analyze the structures and energies of the iodoplumbate complexes in the form of simple complex of [PbI_(m)L_(n)]^(2-m))_(x) and polymeric iodoplumbates of([PbI_(m)L_(n)]^(2-m))_(x). Based on the calculated formation enthalpies, we propose reaction schemes of MAPbI_(3) formation in DMSO, DMF and DMF-DMSO binary solvent and explain the advantages of the binary solvent.We highlight the important role of NH...O hydrogen bonds in the formation of iodoplumbates monomers.Our calculations indicate unbalanced reaction energies at several elementary reaction steps in either DMF(formation of [PbI_(4)L_(n)]^(2-) being highly favourable) or DMSO(formation of [PbI_(5)L_(n)]^(3- )being retarded).Mixing a small amount of DMSO in DMF gives rise to a better balance in the energies and, therefore,potentially better equilibria in the overall crystallization process and better quality of the final perovskite films.

Nitridation of Ni-based alloys:thermodynamics,kinetics,and deformation phenomena accompanying internal precipitation

When a moderately stable phase is precipitated out during an intemal reaction, the behaviour of the penetrating atoms within the diffusion zone can be interpreted based on thermodynamic considerations. Evidence for “up-hill” diffusion of the penetrating species through the matrix towards the precipitation front during the intemal nitridation of Ni-Cr alloys at 1125℃ and 6000 bar of N2-pressure was predicted. Such behaviour of nitrogen is opposite to the boundary conditions in Wagner＇s description of internal reactions. A volume change associated with the precipitation reaction resulted in a stress gradient between the alloys surface and the intemal nitridation front. Stress relief occurred mainly by transport of nickel to the gas/metal interface. Pipe diffusion-controlled creep is the dominant stress accommodation mechanism during nitriding of dilute Ni-Cr alloys at 700℃ under a flowing NH3 ＋ H2 gas mixture.

Liquid-Liquid Equilibrium for Extraction of Benzene from 1-Hexene Using Two Different Solvents

Two different solvents had been used to separate benzene from 1-hexene under atmosphere pressure by employing one of the following two solvents, viz.: dimethyl sulfoxide (DMSO) at 298.15 K and 318.15 K, and furfural at 298.15 K. A series of liquid-liquid equilibrium (LLE) data had been obtained and the distribution coefficient together with the separation factor were calculated from them. Both the NRTL and the UNIQUAC models could fit in with the experimental data quite well.