QUALITY ASSURANCE AND QUALITY CONTROL IN ESTIMATES OF ENVIRONMENTAL EXPOSURES FOR HUMAN RISK ASSESSMENT

Measurements of environmental and human sanples requires dataof known quality.The basis to obtain such measurements is in awell designed and executed quality assurance and quality controlprogram.In the measurement of mutagenesis and other genotoxicendpoints in environmental and human samples,QA/QC programs arestill in the stages of development,as evidenced by the lack ofagreement of resuits from laboratory to laboratory.The purposeof this is to elucidate the principles,requirements andstrategies for the development or improvement of a qualityassurance and quality control program in order to providecredible data and,second,to promote an understanding of thecomponents of the QA/QC program to evaluate the accuracy,biasand precision of environmental and human biological monitoringgenotoxic data forming the basis for estimates of environmentalexposures for human risk assessment.Such risk assessments canprovide the basis for critical decisions on vital matters rangingfrom the health of individuals to the

Enhanced photocatalytic activity of methylene blue using heterojunction Ag@TiO_(2)nanocomposite:Mechanistic and optimization study

The objective in this study is to investigate the adsorption-degradation of the methylene blue(MB)dye using a fabricated heterojunction Ag@TiO_(2)nanocomposite.The batch factors used in photo catalytic reactions were pH,UV-irradiation time,temperature,catalytic dosage,and concentration of MB.The results showed that 0.2×10^(3) g·ml^(-1))of the catalytic dose caused the Ag@TiO_(2)adsorption to degrade by 96.67%with darks and UV exposure.Using the Langmuir-Hinshelwood model to determine the kinetic,the Ag@TiO_(2)displays a greater kinetic rate than TiO_(2)and silver nanoparticle(AgNPs).The photocatalytic degradation of MB,which is an endothermic reaction involving all catalysts,is shown by the thermodynamic parameter to have the positive value of enthalpy(ΔH°).The enthalpies observed were Ag@TiO_(2)(126.80 kJ·mol^(-1))<AgNPs(354.47 kJ·mol^(-1))<TiO_(2)(430.04 kJ·mol^(-1)).Ascorbic acid(·OH scavenger),2-propanol(·O_(2)scavenger),and ammonium oxalate(AO)(hole h+scavenger)were employed to conduct the scavenger effects.The Ag@TiO_(2)demonstrated a reduction in MB degradation when combined with 2-propanol,and this clearly demonstrated that,in contrast to hydroxyl radicals(·OH)and holeh scavengers,superoxide radical anion(O_(2)scavenger)plays a significant role in MB degradation.Utilizing density functional theory(DFT)to elucidate the mechanism and B3LYP/6-311+G(d,p)level optimization,the degradation-adsorption process was explained.When the N-N,C-N or C-C bonds were severed,the Fukui faction was demonstrated for nucleophilic,electrophilic,and radical attack.

Synthesis of silver nanoparticle with Colocasia esculenta(L.) stem and its larvicidal activity against Culex quinquefasciatus and Chironomus sp

Objective:To synthesize silver nanoparticles with Colocasia esculenta as a reducing agent and to evaluate their effect against Culex quinquefasciatus and Chironomus sp.Methods:The aqueous extract of Colocasia esculenta stem was used for nanosynthesis.The synthesized nanoparticles were characterized by UV-Vis spectrophotometry,Fourier-transform infrared spectroscopy,scanning electron microscope,transmission electron microscopy,energy-dispersive X-ray spectroscopy,X-ray diffraction and Zeta potential studies.The toxicity of Colocasia esculenta stem extract and the synthesized silver nanoparticles was evaluated against the larval stages of target human filarial vector Culex quinquefasciatus and non-target Chironomus sp.Results:Scanning electron microscopy and transmission electron microscopy studies revealed almost spherical shape of the synthesized silver nanoparticles with size ranging from 13-50 nm.After 24 hours of exposure,the LC50 and LC90 of the plant extract against 4th instars larvae of Culex quinquefasciatus were 745.56 mg/L and 1258.28 mg/L,respectively,which were higher than those of synthesized silver nanoparticles(5.17 mg/L and 17.32 mg/L after 24 h;1.58 mg/L and 13.01 mg/L after 48 h).In addition,the LC50 and LC90 of silver nanoparticles against Chironomus sp.were 9.71 mg/L and 23.15 mg/L after 24 h as well as 2.38 mg/L and 19.49 mg/L after 48 h,respectively.Conclusions:The aqueous stem extract of Colocasia esculenta is a good agent for synthesis of silver nanoparticles,which are almost spherical with size less than 30 nm.The synthesized nanoparticles show good larvicidal activity without any harmful effect on non-target species.

Assessment of physicochemical properties of water and their seasonal variation in an urban river in Bangladesh

To assess the magnitude of water quality decline in the Turag River of Bangladesh,this study examined the seasonal variation of physi-cochemical parameters of water,identified potential pollution sources,and clustered the monitoring months with similar characteristics.Water samples were collected in four distinct seasons to evaluate temperature,pH,dissolved oxygen(DO)concentration,five-day biochemical oxygen demand(BOD 5),chemical oxygen demand(COD),electrical conductivity(EC),chloride ion(Cl^(-))concentration,total alkalinity(TA),turbidity,total dissolved solids(TDS)concentration,total suspended solids(TSS)concentration,and total hardness(TH)using standard methods.The analytical results revealed that 40%of water quality indices were within the permissible limits suggested by different agencies,with the exception of EC,Cl^(-)concentration,TA,turbidity,DO concentration,BOD 5,and COD in all seasons.Statistical analyses indicated that 52%of the contrasts were significantly different at a 95%confidence interval.The factor analysis presented the best fit among the parameters,with four factors explaining 94.29%of the total variance.TDS,BOD 5,COD,EC,turbidity,DO,and Cl?were mainly responsible for pollution loading and were caused by the significant amount of industrial discharge and toxicological compounds.The cluster analysis showed the seasonal change in surface water quality,which is usually an indicator of pollution from rainfall or other sources.However,the values of different physico-chemical properties varied with seasons,and the highest values of pollutants were recorded in the winter.With the change in seasonal tem-perature and increase in rainfall,the seasonal Turag River water followed a self-refining trend as follows:rainy season>pre-winter>summer>winter.

Implementation of the Air Quality Monitoring Network at Agadir City in Morocco

Air pollution is a major global issue with widely known harmful effects on human health and the environment. This pollution is a very complex phenomenon given the diversity of pollutants that may be present in the atmosphere. The air quality in urban areas is of a great concern for residents living in cities and represents a current issue that requires an adequate management. So that air quality policy is driven by health concerns. In this paper, we present an overview on the experience of Agadir city to establish the air quality management policy, local authority on the whole have developed a good understanding of air quality in the area. Indeed for several years, efforts have been made to monitor the air quality in this city, this translated by air quality assessment since 2006 using mobile laboratory and fixed station. Our goals in this study were to review the operation of Local Air Quality Management (LAQM) making better use of available resources to improve its outcomes and make recommendations with a view to improving air quality issues. This work highlights the requirement to revise periodically the LAQM for generating priority for air quality issues within local authority and the need to implement the optimizing Air Quality Monitoring Network (AQMN).

Impact of Domestic Solid Waste Management on Wet Land Water Quality: Case of Abomey-Calavi Municipality in Benin Republic

The waste management is a major environmental challenge in all the countries. In the Republic of Benin, in absence of controlled landfill, the wetlands are filling in by solid household waste to set up housing environments. This study aimed at identifying the various forms of wetlands water pollutions originated by this practice. Physico-chemical parameters of sampling water were determined by using Ionic chromatography and spectrometry of atomic absorption. The microorganisms indicating fecal peril were identified by the conventional techniques of microbiology. Water quality of a witness well was also used to assess the general water quality of the backfilled wetland. The results revealed the water samples collected from backefilled wetlands were mineralized (898.32 ± 6.13 μs/cm), rich in chlorinate (237.80 ± 4.23 mg/L) and nitrates ions (224.10 ± 3.42 mg/L). They are more colored (399.23 ± 3.01 Pt/Co) and more turbid (62.5 ± 2.48 NTU) than those of the unfilled wetlands. The results of microbiological analysis shown the presence of the cysts of Giardia lamblia (590/100 L) and cysts of Entamoeba histolytica (13/100 L) in all water, except those of witness well. The frequency of water contamination by bacteria indicating general degradation is 86.4%. The embankment of the wetlands by the solid household waste leads to the water pollution.

Trace metal dynamics in an industrialized Brazilian river:A combined application of Zn isotopes,geochemical partitioning,and multivariate statistics

The Paraiba do Sul(PSR)and Guandu Rivers(GR)water diversion system(120 km long)is located in the main industrial pole of Brazil and supplies drinking water for 9.4 million people in the metropolitan region of Rio de Janeiro.This study aims to discern the trace metals dynamics in this complex aquatic system.We used a combined approach of geochemical tools such as geochemical partitioning,Zn isotopes signatures,and multivariate statistics.Zinc and Pb concentrations in Suspended Particulate Matter(SPM)and sediments were considerably higher in some sites.The sediment partition of As,Cr,and Cu revealed the residual fraction(F4)as the main fraction for these elements,indicating low mobility.Zinc and Pb were mostly associated with the exchangeable/carbonate(F1)and the reducible(F2)fractions,respectively,implying a higher susceptibility of these elements to being released from sediments.Zinc isotopic compositions of sediments and SPM fell in a binary mixing source process between lithogenic(δ^(66/64)Zn_(JMC)≈+0.30‰)and anthropogenic(δ^(66/64)Zn_(JMC)≈+0.15‰)end members.The lighterδ^(66/64)Zn_(JMC)values accompanied by high Zn concentrations in exchangeable/carbonate fraction(ZnF1)enable the tracking of Zn anthropogenic sources in the studied rivers.Overall,the results indicated that Hg,Pb,and Zn had a dominant anthropogenic origin linked to the industrial activities,while As,Cr,and Cu were mainly associated with lithogenic sources.This work demonstrates how integrating geochemical tools is valuable for assessing geochemical processes and mixing source effects in anthropized river watersheds.