In 2007, the American Medical Association and the Ameri- can College of Sports Medicine co-launched a health initiative called ＂Exercise is Medicine＂. It soon became a multinational collaboration, currently involvin...In 2007, the American Medical Association and the Ameri- can College of Sports Medicine co-launched a health initiative called ＂Exercise is Medicine＂. It soon became a multinational collaboration, currently involving 43 national centers across the globe.1 Moreover, the slogan ＂Exercise is Medicine＂ has quickly spread outside healthcare settings and has become a popular discourse surrounding exercise. In recent years, however, some exercise scientists began to question if the medical model of exercise makes it an attractive approach for promoting exercise. In this special issue of Journal of Sport and Health Science, we present the views of leading researchers in exercise sociology, sport and exercise psychology, exercise physiology, as well as sports and exercise medicine who par- ticipated in an international symposium on Physical activity continuum throughout the lifespan： Is exercise a medicine or what？. This symposium was organized by the Shanghai Jiao Tong University and the China Sport Science Society in Shanghai on November 11-12, 2015.展开更多
The substantia nigra pars reticulate(SNr),which plays a pivotal role in motor control,is the key structure in integrating information for cortex,basal ganglia and thalamus.Abnormal gait and posture deficits can be rev...The substantia nigra pars reticulate(SNr),which plays a pivotal role in motor control,is the key structure in integrating information for cortex,basal ganglia and thalamus.Abnormal gait and posture deficits can be reversed by SNr deep brain stimulation(DBS)in certain Parkinson’s disease cases.However,functional characterization of SNr,which is the key for the optimization of DBS effect,remains elusive.In current study,we recorded extracellular single unit in SNr of urethane anesthetized rats.We have found that urethane can induce slow delta and theta oscillations in SNr local field potential.The high gamma oscillation observed is positively correlated with the occurrence of action potential.The putative GABAergic neurons have a mean firing rate of(20.82±2.04)Hz,of which 65.2%display a regular firing pattern and 34.8%show irregular firing.Our results demonstrated the heterogeneous property of SNr and provided possible theoretical basis for promoting the next generation of DBS electrode design and optimization of clinical DBS parameters.展开更多
文摘In 2007, the American Medical Association and the Ameri- can College of Sports Medicine co-launched a health initiative called ＂Exercise is Medicine＂. It soon became a multinational collaboration, currently involving 43 national centers across the globe.1 Moreover, the slogan ＂Exercise is Medicine＂ has quickly spread outside healthcare settings and has become a popular discourse surrounding exercise. In recent years, however, some exercise scientists began to question if the medical model of exercise makes it an attractive approach for promoting exercise. In this special issue of Journal of Sport and Health Science, we present the views of leading researchers in exercise sociology, sport and exercise psychology, exercise physiology, as well as sports and exercise medicine who par- ticipated in an international symposium on Physical activity continuum throughout the lifespan： Is exercise a medicine or what？. This symposium was organized by the Shanghai Jiao Tong University and the China Sport Science Society in Shanghai on November 11-12, 2015.
基金the Science and Technology Commission of Shanghai Municipality(No.18JC1413100)the National Key Research and Development Program(No.2016YFC0906400)。
文摘The substantia nigra pars reticulate(SNr),which plays a pivotal role in motor control,is the key structure in integrating information for cortex,basal ganglia and thalamus.Abnormal gait and posture deficits can be reversed by SNr deep brain stimulation(DBS)in certain Parkinson’s disease cases.However,functional characterization of SNr,which is the key for the optimization of DBS effect,remains elusive.In current study,we recorded extracellular single unit in SNr of urethane anesthetized rats.We have found that urethane can induce slow delta and theta oscillations in SNr local field potential.The high gamma oscillation observed is positively correlated with the occurrence of action potential.The putative GABAergic neurons have a mean firing rate of(20.82±2.04)Hz,of which 65.2%display a regular firing pattern and 34.8%show irregular firing.Our results demonstrated the heterogeneous property of SNr and provided possible theoretical basis for promoting the next generation of DBS electrode design and optimization of clinical DBS parameters.
