The kilns of Chenlu Town, Tongchuan City, Shaanxi Province, have been firing for the past 1,400 years. Ceramics production methods in Chenlu date back to the famous Tang Dynasty （618-907） Yaozhou Kiln, and the quali...The kilns of Chenlu Town, Tongchuan City, Shaanxi Province, have been firing for the past 1,400 years. Ceramics production methods in Chenlu date back to the famous Tang Dynasty （618-907） Yaozhou Kiln, and the quality of their products remains peerless. The demand for Yaozhou ceramic reached its zenith during the Song Dynasty （960-1279）, when they were regarded as the ultimate imperial tribute.展开更多
We have previously described a simple method to analyze the chromatin structure of Arabidopsis telomeres independently of that of Interstitial Telomeric Sequences (ITSs). By using this method, we found that, whereas I...We have previously described a simple method to analyze the chromatin structure of Arabidopsis telomeres independently of that of Interstitial Telomeric Sequences (ITSs). By using this method, we found that, whereas ITSs are heterochromatic, Arabidopsis telomeres exhibit euchromatic features [1]. Some concerns have been recently raised about the accuracy of this procedure [2]. Here, we summarize these concerns and justify our experimental approaches and interpretation of results.展开更多
We have read with interest the article “Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α” by Arnoult and colleagues [1]. This study focuses on human telomeric chrom...We have read with interest the article “Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α” by Arnoult and colleagues [1]. This study focuses on human telomeric chromatin structure using different techniques like Chromatin Immunoprecipitation (ChIP), cytolocalization or RT-qPCR. However, it has been performed without taking into consideration the presence of Interstitial Telomeric Sequences (ITSs) in the human genome. Some of the conclusions of the article are undoubtedly clear but there are others that might be explained in alternative ways, considering the existence of ITSs. Following, we mention some comments that arise from this interesting article.展开更多
XIAO An tightly grips his BMX's handlebars as he soars through the air. He lands, rolls back over some rocks, pedals forwards again and 'bunnyhops' over still more large stones. Then he steadies the bike. ...XIAO An tightly grips his BMX's handlebars as he soars through the air. He lands, rolls back over some rocks, pedals forwards again and 'bunnyhops' over still more large stones. Then he steadies the bike. With a sudden jump from the pedals, and展开更多
文摘The kilns of Chenlu Town, Tongchuan City, Shaanxi Province, have been firing for the past 1,400 years. Ceramics production methods in Chenlu date back to the famous Tang Dynasty （618-907） Yaozhou Kiln, and the quality of their products remains peerless. The demand for Yaozhou ceramic reached its zenith during the Song Dynasty （960-1279）, when they were regarded as the ultimate imperial tribute.
文摘We have previously described a simple method to analyze the chromatin structure of Arabidopsis telomeres independently of that of Interstitial Telomeric Sequences (ITSs). By using this method, we found that, whereas ITSs are heterochromatic, Arabidopsis telomeres exhibit euchromatic features [1]. Some concerns have been recently raised about the accuracy of this procedure [2]. Here, we summarize these concerns and justify our experimental approaches and interpretation of results.
文摘We have read with interest the article “Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α” by Arnoult and colleagues [1]. This study focuses on human telomeric chromatin structure using different techniques like Chromatin Immunoprecipitation (ChIP), cytolocalization or RT-qPCR. However, it has been performed without taking into consideration the presence of Interstitial Telomeric Sequences (ITSs) in the human genome. Some of the conclusions of the article are undoubtedly clear but there are others that might be explained in alternative ways, considering the existence of ITSs. Following, we mention some comments that arise from this interesting article.
文摘XIAO An tightly grips his BMX's handlebars as he soars through the air. He lands, rolls back over some rocks, pedals forwards again and 'bunnyhops' over still more large stones. Then he steadies the bike. With a sudden jump from the pedals, and
