Chamomile (<em>Matricaria recutita L</em>) and Chrysanthemum (<em>Chrysanthemum coronarium L. </em>(Garland)) are plants belonging to the family <em>Asteraceae</em>. The pharmacolog...Chamomile (<em>Matricaria recutita L</em>) and Chrysanthemum (<em>Chrysanthemum coronarium L. </em>(Garland)) are plants belonging to the family <em>Asteraceae</em>. The pharmacological properties of these herbs result from interactions among their many components. Of these, over 120 secondary metabolites with pharmacological and/or potential pesticide activity have been identified. The diverse chemical and biological characteristics of this set of compounds, <em>i.e.</em>, essential oils and organic extracts of genera <em>Matricaria</em> and <em>Chrysanthemum</em>, have been shown to have particular pesticidal effects, especially those rich in pyrethroids. This work characterizes chamomile and chrysanthemum extracts for their pesticidal properties and their effects following acute exposure in rats. Results show hepatotoxic and oxidative stress-inducing effects in the livers of rats exposed to<em> C. coronarium</em> extracts, but not those of <em>M. recutita</em>.展开更多
In many ways,cancer cells are different from healthy cells.A lot of tactical nano-based drug delivery systems are based on the difference between cancer and healthy cells.Currently,nanotechnology-based delivery system...In many ways,cancer cells are different from healthy cells.A lot of tactical nano-based drug delivery systems are based on the difference between cancer and healthy cells.Currently,nanotechnology-based delivery systems are the most promising tool to deliver DNA-based products to cancer cells.This review aims to highlight the latest development in the lipids and polymeric nanocarrier for siRNA delivery to the cancer cells.It also provides the necessary information about siRNA development and its mechanism of action.Overall,this review gives us a clear picture of lipid and polymer-based drug delivery systems,which in the future could form the base to translate the basic siRNA biology into siRNA-based cancer therapies.展开更多
文摘Chamomile (<em>Matricaria recutita L</em>) and Chrysanthemum (<em>Chrysanthemum coronarium L. </em>(Garland)) are plants belonging to the family <em>Asteraceae</em>. The pharmacological properties of these herbs result from interactions among their many components. Of these, over 120 secondary metabolites with pharmacological and/or potential pesticide activity have been identified. The diverse chemical and biological characteristics of this set of compounds, <em>i.e.</em>, essential oils and organic extracts of genera <em>Matricaria</em> and <em>Chrysanthemum</em>, have been shown to have particular pesticidal effects, especially those rich in pyrethroids. This work characterizes chamomile and chrysanthemum extracts for their pesticidal properties and their effects following acute exposure in rats. Results show hepatotoxic and oxidative stress-inducing effects in the livers of rats exposed to<em> C. coronarium</em> extracts, but not those of <em>M. recutita</em>.
文摘In many ways,cancer cells are different from healthy cells.A lot of tactical nano-based drug delivery systems are based on the difference between cancer and healthy cells.Currently,nanotechnology-based delivery systems are the most promising tool to deliver DNA-based products to cancer cells.This review aims to highlight the latest development in the lipids and polymeric nanocarrier for siRNA delivery to the cancer cells.It also provides the necessary information about siRNA development and its mechanism of action.Overall,this review gives us a clear picture of lipid and polymer-based drug delivery systems,which in the future could form the base to translate the basic siRNA biology into siRNA-based cancer therapies.
