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Heat shock protein 90 is a potential therapeutic target for ameliorating skeletal muscle abnormalities in Parkinson's disease
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作者 Nour Erekat Ahed Al-Khatib Muhammed Al-Jarrah 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第6期616-621,共6页
Previous studies have confirmed that heat shock protein 90 overexpression can lead to dopami- nergic neuronal death. This study was designed to further investigate what effects are produced by heat shock protein 90 af... Previous studies have confirmed that heat shock protein 90 overexpression can lead to dopami- nergic neuronal death. This study was designed to further investigate what effects are produced by heat shock protein 90 after endurance exercise training. Immunohistochemistry results showed that exercise training significantly inhibited heat shock protein 90 overexpression in the soleus and gastrocnemius in Parkinson's disease rats, which is a potential therapeutic target for ameliorating skeletal muscle abnormalities in Parkinso^s disease. 展开更多
关键词 nerve regeneration heat shock protein 90 Parkinson's disease exerecise soleus muscle gastrocnemius muscle skeletal muscle treadmill excise neural regeneration
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