Occupation-related airborne diseases: Management and prevention of tuberculosis among nurses working in Ekiti State University Teaching Hospital

Objective:More health workers die from infectious diseases such as tuberculosis(TB)than from any other infectious agent,so the current study is designed to assess TB treatment and preventive measures as they relate to nursing care practice.Materials and Methods:A cross-sectional study was conducted among 82 nurses from December 2022 to January 2023.The data were collected through a self-developed questionnaire and analyzed by frequency table and analysis of variance(ANOVA)statistics.Results:The researchers found that nurses have sufficient knowledge on Infection Prevention and Control(IPC)policy,but not all nurses follow this management protocol,and the reason for their action is addressed in this study.The management and preventive measures used by the participants were identified as:proper cough etiquette/hygiene,working in a well-ventilated area,use of mask,appropriate disposal of used items and so on was reported.Moreover,this study also discovered that there is a positive correlation between nurses who had received training in IPC policy and their use of airborne preventive measures for TB patients(F=1.87,P=0.002)as well as a positive correlation between the availability of resources and their adherence to the proper use of airborne preventive measures when caring for TB patients(F=1.96,P˂0.001).Conclusion:We proposed infection and control training for nurses and adequate equipment supplies to the TB ward which are required in quick TB diagnosis,and must be carried out on a regular basis by health-care personnel,for efficient nursing practice.Ensuring proper safety equipment and isolation units should be available and assessable for nurses or other health workers showing sign or symptoms of TB.Similarly,it is necessary for government to put in place the control and regulations that will safeguard nurses and mandate them to adopt TB prevention protocols,which will aid in lowering the prevalence of TB among nurses.

The gravity field and gravity data reduction across the continental area of Nigeria

This research presents the variation of the gravity field and associated gravity field components over the continental area of Nigeria to provide data for geoscience research,geodetic and engineering works,aerodynamic studies and deep crustal inferences.Accurate positions and elevations were observed at 58 of the 59 base stations of the Primary Gravity Network of Nigeria(PGNN),whose absolute gravity values had been accurately determined.The absolute gravity values were plotted against their respective positions to reveal the distribution pattern and strength of the gravity field within the study area.Theoretical gravity values at each base station were generated using the Somigliana's equation.The free-air gravity and free-air anomaly gravity values were generated with respect to the World Geodetic System 1984(WGS84)ellipsoid using GPS-derived elevation data.Then,the perturbing potential,free-air gravity with respect to the geoid,and the indirect effects were evaluated.The average of the indirect effects was used to adjust the WGS84 gravity formula to produce a gravity formula that better approximates the geoid across the continental area of Nigeria,compatible with the heights measured relative to the geoid,which can serve as a reference for establishing a vertical height control.The Bouguer gravity and Bouguer gravity anomalies across Nigeria revealed a“trans-southern gravity high strip”interpreted to be associated with mantle upwelling.Two new major mega-lineaments related to mantle upwelling were mapped.A batholith province trending NWeSE was delineated,occurring from north central Nigeria to the north western region and containing closures of“Bouguer gravity lows”interpreted as batholiths.A separate closure of“Bouguer gravity low”was detected at Azare,north eastern Nigeria,which may be due to the presence of intrusive granitic body.It is recommended that the mantle structure beneath“the trans-southern gravity high strip”,“delineated batholith province”and“isolated gravity closures”around the northeast of Nigeria should be studied from seismic shear wave splitting analysis for better understanding of the deep lithospheric structures and moho relief.

Assessment of ERA5 and ERA-Interim in Reproducing Mean and Extreme Climates over West Africa

In situ data in West Africa are scarce,and reanalysis datasets could be an alternative source to alleviate the problem of data availability.Nevertheless,because of uncertainties in numerical prediction models and assimilation methods,among other things,existing reanalysis datasets can perform with various degrees of quality and accuracy.Therefore,a proper assessment of their shortcomings and strengths should be performed prior to their usage.In this study,we examine the performance of ERA5 and ERA-interim(ERAI)products in representing the mean and extreme climates over West Africa for the period 1981-2018 using observations from CRU and CHIRPS.The major conclusion is that ERA5 showed a considerable decrease in precipitation and temperature biases and an improved representation of inter-annual variability in much of western Africa.Also,the annual cycle is better captured by ERA5 in three of the region’s climatic zones;specifically,precipitation is well-reproduced in the Savannah and Guinea Coast,and temperature in the Sahel.In terms of extremes,the ERA5 performance is superior.Still,both reanalyses underestimate the intensity and frequency of heavy precipitations and overestimate the number of wet days,as the numerical models used in reanalyses tend to produce drizzle more often.While ERA5 performs better than ERAI,both datasets are less successful in capturing the observed long-term trends.Although ERA5 has achieved considerable progress compared to its predecessor,improved datasets with better resolution and accuracy continue to be needed in sectors like agriculture and water resources to enable climate impact assessment.

Protein kinase inhibitors affect spermatogenic functions and blood testis barrier remodelling:A scoping review

Objective:To identify the role of protein kinase in male reproduction in animal models and human spermatogenic function.Methods:This study assessed the protein kinase of male reproduction in animal models and human using different reviewed paper indexed in PubMed,Science Direct,EBSCO,Scopus,Cochrane Library,Sage Journals,and Google Scholar.Data were charted based on author,year of publication published between 1893 and 2023,country,purpose,data collection,key findings,and research focus/domain.Results:The MAPK pathway contributed to the growth,maturation,and functionality of male germ cells.We also found out that certain influencing factors categorized into hormonal/non hormonal factors and chemotoxicant,as well as heat stress expressed an inhibitory mechanism on protein kinase,thus affecting spermatogenic functions and maintenance/remodeling of the blood testis barrier,as well as the physiology of the Sertoli cells necessary for nutritional support of spermatogenesis.However,activating protein kinases pathway like the mTOR pathway as well as increased expression of peroxiredoxin-4 and L-carnitine mediated protein kinases may be useful for treating or managing male reproductive dysfunction.Conclusions:Protein kinase plays an important role in spermatogenic functions and blood testis remodeling in animal and human.Its assessment provides essential information that can guide treatment strategies aimed at improving male reproductive potential.Taken together,these recent advances highlight a future therapeutic intervention in assessing male reproductive potential.It might also be possible to look at potential targets for male contraceptives in the MAPK pathway.

Traditional medicine use during pregnancy and labor in African context:A scoping review

Traditional medicine(TM)has been more popular among pregnant women worldwide and has played a significant part in maternal health-care services in many nations.Herbs,herbal preparations,and finished herbal products all contain active substances that are derived from plant parts or other plant components that are thought to have medicinal advantages.To diagnose,prevent,and treat illnesses as well as to enhance general well-being,about 80%of people use a variety of TM,including herbal remedies.A systematic search of Google Scholar and PubMed was performed utilizing an established scoping review framework by Joanna Briggs Institute from January 2012 to December 2022.A consequent title and abstract review of articles published on TM in the African context were completed.Of over 15,000 published studies identified,15 meeting the inclusion criteria were integrated into the following seven categorical themes:prevalence of TM use,source of information on TM use,reasons for use of TM,route of administration,common herbs used in pregnancy and labor,the effect of herbs used in pregnancy and labor,and predictors of use of TM.The studies reviewed were primarily in the context of an African setting on the use of TM regarding herbal medicine.Of all the articles,the highest number of studies was conducted in Zimbabwe.This review shows increased use of TM by women during pregnancy and labor with a reported prevalence rate varying from 12%to 60%.However,a decrease in use in the third trimester of pregnancy was reported.The most frequent source of information on the use of TM was from family and friends,while age,parity,education,and income were factors affecting use.In conclusion,the participants do not often disclose the use of TM during their antenatal attendance and the reason for use was accessibility and cost.Therefore,there is a need for further study on the safety and efficacy of TM use in pregnancy and labor.

Synthesis, SAR, and in Silico ADME Screening Studies of Some 9-Amino-3-Phenylacridone Derivatives as Topoisomerase II Inhibitors

Cancer is a leading cause of death globally, claiming about 9.6 million lives and approximately 420 million new cases of cancer will be diagnosed in the world by the year 2025. The aim of this study was to synthesize and computationally evaluate pharmacological potential of some derivatives of 9-amino-3-phenylacridone, as topoisomerase II (Topo II) inhibitors. In this study, 10 derivatives of 3-phenyl-9-aminoacridone were chemically synthesized and characterized, and the potential pharmacological indications of these compounds were computationally predicted by methods such as ADMET prediction, molecular target prediction and molecular docking. The results showed that two derivatives (58e and 58j) were non-permeant of blood-brain barrier, and this property was found similar to that of amsacrine and etoposide. The results of molecular docking of the ten derivatives of 3-phenyl-9-aminoacridone that were synthesized in this work showed that the synthetic compounds (58a-j) and the standard drugs have overall best binding affinities for human acetylcholine esterase than butyrylcholinesterase, and overall best binding affinities for human topo IIα than human topo IIβ. Overall, the results of this study suggest that the synthetic compounds 58a, 58c, 58f, 58g, and 58i could probably inhibit topo IIα by catalytic inhibition as seen with amsacrine, but only 58b and 58e possessed DNA non-intercalation properties as seen with etoposide, serving as topo II poison. In conclusion, this study showed that 3-phenyl-9-aminoacridone derivatives are potential inhibitor of topo IIα/β both by catalytic inhibition and poison as non-intercalator of DNA.

Source, Contamination Assessment and Risk Evaluation of Heavy Metals in the Stream Sediments of Rivers around Olode Area SW, Nigeria

In order to investigate the source,contamination,and risk of heavy metals such as Pb,Zn,Cu,Ni,Co,Fe,Mn,and Cr,twelve(12)stream sediments and ten(10)rock samples were collected from pegmatite mining sites at Olode and its environs inside Ibadan,Southwestern Nigeria.The average values and order of abundance obtained followed the pattern:Mn(595.09)>Ba(80)>Cr(50.82)>V(45.09)>Zn(29.73)>Cu(13.82)>Co(13.82)>Sr(10.46)>Ni(9.73)>Pb(9.09)>Fe(1.59).These were greater than the background values,indicating that mining has a negative impact on the study area,as indicated by the high coefficient of variation and correlation values(>0.6)for Copper-Lead(0.929),Copper-Vanadium(0.970),Copper-Chromium(0.815),Lead-Vanadium(0.884),and others.On the basis of the enrichment factor(EF),the Olode sediments show extremely high enrichment for Mn and Ba in the research region.Cu and Ni are most likely to blame for the elevated contamination levels,according to CF values.The degree of contamination(CD),pollution load index(PLI),pollution index(PI),and modified pollution index(MPI)all revealed high levels of contamination in all stream sediment samples,whereas Igeo shows that the Olode stream sediments are“practically uncontaminated to extremely contaminated by Ni,Co,and Mn”.Ni and Cu are the major regulating factors that are most likely causing the possible Eri.As a result,these findings give important information for conducting appropriate ecological management research.

Blast-induced ground vibration prediction in granite quarries:An application of gene expression programming,ANFIS,and sine cosine algorithm optimized ANN

Blasting of rocks has intrinsic environmental impacts such as ground vibration,which can interfere with the safety of lives and property.Hence,accurate prediction of the environmental impacts of blasting is imperative as the empirical models are not accurate as evident in the literature.Therefore,there is need to consider some robust predictive models for accurate prediction results.Gene expression programming(GEP),adaptive neuro-fuzzy inference system(ANFIS),and sine cosine algorithm optimized artificial neural network(SCA-ANN)models are proposed for predicting the blast-initiated ground vibration in five granite quarries.The input parameters into the models are the distance from the point of blasting to the point of measurement(D),the weight of charge per delay(W),rock density(q),and the Schmidt rebound hardness(SRH)value while peak particle velocity(PPV)is the targeted output.100 datasets were used in developing the proposed models.The performance of the proposed models was examined using the coefficient of determination(R2)and error analysis.The R2 values obtained for the GEP,ANFIS,and SCA-ANN models are 0.989,0.997,and 0.999,respectively,while their errors are close to zero.The proposed models are compared with an empirical model and are found to outperform the empirical model.

Ethylacetate extract of red onion(Allium cepa L.)tunic affects hemodynamic parameters in rats

The effects of ethylacetate extract of red onion(Allium cepa)tunic(ACTE)on some hemodynamic and biochemical parameters were evaluated in normotensive albino rats.Blood pressure parameters were determined in anaesthetized rats orally administered ACTE(10-,20-,or 40 mg/kg)or ramipril(1 mg/kg)once daily for 14 days.Respectively,10-,20-,or 40 mg/kg ACTE produced significant(P<0.01),dose-dependent fall in systolic blood pressure,SBP(21%,27%,33%),diastolic blood pressure,DBP(6%,10%,16%),pulse pressure,PP(42%,49%,56%),mean arterial blood pressure,MAPB(13%,18%,23%)and heart rate,HR(4%,5%,7%).The highest effective dose(40 mg/kg)compared well with ramipril(1 mg/kg)with regards to SBP(41%),DBP(19%),PP(70%),MABP(29%)and HR(10%).Similar trends(decreases)were recorded for 40 mg/kg ACTE and ramipril,respectively,as regards the activities of serum enzymes:creatine kinase(60%and 65%),ALT(18%and 14%)and ALP(28%and 16%).HPLC fingerprints of the flavonoid-rich ACTE revealed that flavonols:quercetin,quercitrin,isoquercitrin,rutin and kaempferol are the active flavonoids.The results demonstrate the hypotensive effect of A.cepa tunic flavonoids initiating further investigation of their individual or synergistic contribution(s)to the observed effects.

Geochemistry and petrogenetic evolution of metasedimentary rocks in Bunu Area,part of Kabba-Lokoja-Igarra schist belt,SW Nigeria

Field and geochemical studies of the Bunu area,SW Nigeria,were carried out on gneiss-metasedimentary rocks that consist of migmatised gneiss,quartz-mica schist,and foliated and massive quartzites.These gneissmetasedimentary rocks are interbedded with meta-igneous rock(amphibolite),all of which are intruded by granitoid and cut by basic and felsic dykes.Geochemical data on major,trace,and rare Earth elements of these rocks from the area were used to speculate on the petrogenetic and geodynamic evolution of the rocks in the area.Compositionally,the metasedimentary rocks in the area have a restricted range of major oxides such as SiO_(2)and Al_(2)O_(3)with low average values of FeO,MnO,CaO,and PO.Concentrations of average values of HSFE such as Zr,Nb,and Y are moderately high in migmatitic gneiss,quartzmica schist,and low in both massive and foliated quartzite.ΣLREE average values are 124.25,132.41,and18.64 ppm respectively for migmatite gneiss,quartz-mica schist,and low in both massive and foliated quartzite.These rocks are also generally enriched in Ba,Cs,Pb,U,Cr,Rb,and Zr and depleted in Be,Sr,Ti,Mo,Th,and W.This enrichment–depletion in major oxides and trace elements of the rocks in this area is probably a consequence of the movement of metamorphic remobilized fluids within the rocks in the area during the Pan-African or earlier events as noted in the adjacent Egbe-Isanlu Schist belt.A further geochemical characterisation of the rocks in the area using Log(Na_(2)O/KO)vs Log(SiO_(2)/Al_(2)O_(3)indicates that while the protolith of migmatised gneiss and quartzmica schist are greywackes to litharenite in compositions that of quartzites are sublitharenite to quartz arenite.On the ternary plot of Al_(2)O_(3)-(CaO+Na_(2)O)-KO for metasedimentary rocks in the area,most migmatitic gneiss and quartz-mica schist rocks plot close to average shale while quartzites mostly tend to illite compositions and almost toward the Al_(2)O_(3)-apex of the diagram attesting to depletion of CaO and Na_(2)O with the removal of KO.CIA vs PIA plot of the rocks in the area shows that while migmatitic-gneiss and quartz-mica schist are moderately weathered,both massive and foliated quartzites are high to extremely weathered.They are all derived mostly from predominantly felsic igneous to quartzose sedimentary provenance and mostly emplaced in passive continental margins.These nature of the protoliths suggests gradual subsidence of the basin during its genesis,and/or tectonic stable or inactive environment from which the sediments were derived.

Water Resource, Hygienic Practice, and Soil Transmitted Helminthiasis in Some Rural Communities of Osun State, Nigeria

Provision of water, sanitation and hygiene (WASH) resources has been advocated as necessary add-on strategy for sustainable control of soil-transmitted helminthiasis (STH) alongside annual mass drug administration (MDA) of albendazole to endemic communities. This study investigated the burden of STH and status of WASH resources in eight rural communities in Aiyedaade LGA, Osun State, Nigeria. Four of the communities were supported with improved water and hygiene resources (Category A), and another four supported only with improved water resources (Category B). Two hundred and sixteen (216) fresh stool samples were collected from consenting community members and screened for Ascaris lumbricoides, Hookworm and Trichuris trichiura infections using ether concentration method. The status and condition of WASH resources were determined using questionnaire and physical observation. An overall prevalence of 35.2% was observed for any STH infection. Species’ prevalence of Ascaris lumbricoides, Hookworm and Trichuris trichiura prevalence was 33.8%, 22.7%, and 0.5% respectively. Intensity of STH infection was significantly higher in Category A communities than in Category B communities. The prevalence of STH in Category A communities was higher (42.0%) than that in Category B communities (30.1%). There were significant differences (p = 0.000) in STH infections between the two categories. The status of improved water supply was not significantly different (p = 0.3153) in the two categories. Knowledge, attitude, and practices about STH, its transmission and control were low in both categories of communities. These results imply that current implementation of WASH which tends to focus on resource distribution, equity, and coverage, is unlikely to impact on STH transmission and control. Therefore, it is necessary for WASH providers to consider STH transmission control in their planning and implementation of WASH intervention for STH endemic communities.

Non-Relativistic Treatment of a Generalized Inverse Quadratic Yukawa Potential

A bound state solution is a quantum state solution of a particle subjected to a potential such that the particle＇s energy is less than the potential at both negative and positive infinity. The particle＇s energy may also be negative as the potential approaches zero at infinity. It is characterized by the discretized eigenvalues and eigenfunctions, which contain all the necessary information regarding the quantum systems under consideration. The bound state problems need to be extended using a more precise method and approximation scheme. This study focuses on the non-relativistic bound state solutions to the generalized inverse quadratic Yukawa potential. The expression for the non-relativistic energy eigenvalues and radial eigenfunctions are derived using proper quantization rule and formula method, respectively. The results reveal that both the ground and first excited energy eigenvalues depend largely on the angular momentum numbers, screening parameters, reduced mass, and the potential depth. The energy eigenvalues, angular momentum numbers, screening parameters, reduced mass, and the potential depth or potential coupling strength determine the nature of bound state of quantum particles. The explored model is also suitable for explaining both the bound and continuum states of quantum systems.

Uptake of in-vitro fertilization among couples attending fertility clinic in a tertiary health institution

Objective:To identify factors that determine the uptake of in-vitro fertilization(IVF),and to determine the predicting effect of the identified factors on the uptake of IVF among couples attending fertility clinic at a tertiary health institution in Benin City,Nigeria.Methods:This study adopted a cross-sectional descriptive design.A self-structured questionnaire tested was validated and administered to 250 couples who attended fertility clinic.Data were collected from March 2021 to June 2021 and were analyzed using the Statistical Package for Social Science(SPSS)version 21.Data were presented and interpreted using descriptive statistics and inferential statistics such as Chi-square,univariate statistics and multivariate logistic regression analysis.Results:Among 250 couples,154(61.6%)were willing to adopt IVF.The multivariate logistic regression analysis showed that catholic religion[odds ratio(OR)0.21,95%confident interval(CI)0.54-0.73],family income(OR 1.50,95%CI 1.10-2.00)and age(OR 1.04,95%CI 1.01-1.10)were the major factors that determined the uptake of IVF,with P-value of<0.001,0.018 and 0.031,respectively.Conclusions:The uptake of IVF could be sustained or improved on,if the government should improve on the cost of living for families,and religious leaders need to be encouraged to pass on the information about IVF to their members to be well guided about the possibilities of IVF.

Reversal of acetaminophen-generated oxidative stress and concomitant hepatotoxicity by a phytopharmaceutical product

The increasing popularity of herbal medicine and the well-established health benefits of phytochemicals have spurred the multiplicity of nutraceutical and phytopharmaceutical products.In this study,Trévo^TM,a nutraceutical and phytopharmaceutical product,was evaluated for beneficial effects in acetaminophen-induced hepatic toxicity in Wistar rats.Animals received Trévo^TM(1.5 mL/kg,3.0 mL/kg or 4.5 mL/kg)orally for 14 days.Hepatotoxicity was induced by the oral administration of acetaminophen(2 g/kg),24 h prior to sacrifice.Biochemical liver function tests,oxidative stress indicators and histoarchitectural changes were evaluated.Acetaminophen administration occasioned significant increase(P<0.05)in serum bilirubin level and activities of the aminotransferases,alkaline phosphatase,γ-glutamyltransferase and lactate dehydrogenase accompanied by a significant decrease(P<0.05)in albumin level as well as histopathological alterations in liver sections.Promotion of hepatic oxidative stress by acetaminophen was revealed by significant(P<0.05)increase in lipid peroxidation,depletion of reduced glutathione,and decrease in superoxide dismutase and catalase activities.Administration of Trévo^TM remarkably ameliorated acetaminophen-induced histopathological alterations and changes in serum and tissue biochemical markers.The protective effect of Trévo^TM(4.5 mL/kg)was at par with that of Silymarin(25 mg/kg).The present study indicates that Trévo^TM has notable salubrious effects.

Ethnobotanical Survey of Medicinal Plants Used in Curing Some Diseases in Infants in Abeokuta South Local Government Area of Ogun State, Nigeria

An ethnobotanical survey of medicinal plants used in curing some diseases in infants in Abeokuta South Local Government Area of Ogun State, Nigeria was carried out between February and June, 2012. Ethnobotanical data were collected by oral interview with the aid of a semi-structured questionnaire administered to fifty (50) respondents made up of traditional medical practitioners (TMPs), herbalists and herb sellers. From the survey, a total of 63 plant species belonging to 33 families were found to be useful in the treatment of cold, malaria, fontanel, diarrhoea, typhoid, chicken pox, measles and small pox. Recipes used in the treatment of these ailments were documented. Herbal remedies were either prepared from dry or freshly collected plants while the traditional solvents of choice includes water, pure honey, lime and aqueous extracts from fermented maize. The methods of preparation were decoction and infusion while method of administration ranges from 1 drop to 1 teaspoonful daily. Survey revealed that leaves form the major part of plant for herbal preparations. Residents in the study area find the traditional medicine cheaper as compared to orthodox medicines. It is therefore implicated that efforts should be made on how to improve on documentation, conservation and standardization of the medicinal plants in Nigeria. Also, attention of the scientists and health officials should be drawn to the importance and various uses of the medicinal plants and they should intensify on the research to reveal other concealed values.

Accession ×Treatment Interaction, Variability and Correlation Studies of Pepper (<i>Capsicum</i>spp.) under the Influence of Arbuscular Mycorrhiza Fungus (<i>Glomus clarum</i>) and Cow Dung

The field experiment was conducted in the Department of Botany, University of Ibadan, Nigeria between September to December 2012. Four accessions of pepper (Capsicum spp.), obtained from Moor plantation in Ibadan and LUTH (Lagos University Teaching Hospital) vegetable garden, Idi-Araba Lagos were evaluated to investigate the morpho-agronomic variability and interaction of accession × treatment × days after transplant in treatment combinations of arbuscular mycorrhizal fungus (Glomus clarum) and cowdung. The experiment was a 4 × 4 factorial arrangement laid out in a randomized complete block design with three replications. The combined analysis of variance showed significant accession, treatment, days after transplant, and accession × treatment interactive effect for most of the growth characters at P 0.01 and P 0.05. The result also showed significant difference in yield related traits of fruits for pepper accessions. The number of leaves per plant was significant and positively associated with plant height (r = 0.516;P 0.05), and highly significant and positively correlated with the number of branches (r = 0.836;P 0.01), but negative and non-significantly related with stem girth. Glomus clarum treated plants responded significantly with higher growth and yield. It suggested that G. clarum treatment had higher potential in influencing crop yield compared to cowdung and untreated plants. This study further explored the relationship between G.

Food Access and Experience of Food Insecurity in Nigerian Households during the COVID-19 Lockdown

The food insecurity experiences and related behaviors of Nigerian households during the COVID-19 lockdown have not been fully discussed. This study was conducted to elicit information on the impact of COVID-19 lockdown on economic and behavioral patterns related to food access. An online-based semi-structured questionnaire distributed through messaging platforms was used to collect information on characteristics, food purchasing behaviour before and during COVID-19 lockdown among respondents. Experience of food insecurity was assessed using Food Insecurity Experience Scale (FIES). A total of 883 responses were received and analyzed using SPSS Version 20.0. Most of the respondents (90.5%) were at home or had stopped going to work due to COVID-19 restrictions. Even though smaller households had higher food expenditure claims than larger households (p = 0.012), the larger the household, the more acute the challenge of economic access to food (p = 0.050). Location (p = 0.000), age (p = 0.003), occupation (p = 0.014) and income level (p = 0.000) were associated with experience of food insecurity. In conclusion, lockdown restrictions increased food expenditure and experience of food insecurity among the respondents and thus we recommend the probe of long-term consequences of deviations from usual food access on undernutrition or overnutrition in Nigerian households.

I must eat what I want: A roadblock to type 2 diabetes management

Globally,type 2 diabetes mellitus(T2DM)is considered as one of the most common diseases,which is associated with irreversible risk factors such as age,gene,race,ethnicity,and reversible factors such as diet,physical activity,and smoking.Noncompliance to dietary regimen is the major factors for rapidly rising incidence of T2DM among developing countries.Recently,elevated HbA1c level has also been considered as one of the leading risk factors for developing microvascular and macrovascular complications.Improvement in the elevated HbA1c level can be achieved through diet management;thus,this study found that improvement in patients’dietary knowledge,attitude toward,and compliance to diet regimen will promote a better control of the disease.In conclusion,the stakeholders(health-care providers,health facilities,agencies involved in T2DM care)should educate the patients on the importance of dietary modification in the disease management.Similarly,there is a need for nurses and other health care professionals to advocate and promote a better holistic management that will encourage patients participation and family involvement in the care.