OBJECTIVES: The purpose of this study was to evaluate whether multislice compu ted tomography(MSCT) provides a reliable, noninvasive imaging modality for ident ification of patients with degenerative aortic valve sten...OBJECTIVES: The purpose of this study was to evaluate whether multislice compu ted tomography(MSCT) provides a reliable, noninvasive imaging modality for ident ification of patients with degenerative aortic valve stenosis(AS) by quantifying the aortic valve area(AVA) in comparison to the accepted diagnostic standard tr ansthoracic echocardiography(TTE). BACKGROUND: Management of patients with degen erative AS is based on the severity of disease. The severity of AS in clinical p ractice is assessed by TTE and classified as mild, moderate, or severe according to the AVA. METHODS: Forty-six patients were examined with contrast-enhanced, electrocardiogram-gated, 16-row MSCT for the evaluation of the diagnostic acc uracy. In 30 patients, quantification of the AVA with MSCT was compared to TTE u sing the continuity equation with Doppler velocity-time integral for calculatio n of the AVA. RESULTS: Sensitivity of MSCT for the identification of patients wi th degenerative AS was 100%, and the specificity was 93.7%. Thirty of 46 patie nts had AS determined by TTE. Quantification of AVA by MSCT(mean AVA=0.94 cm2) i n patients with AS showed a good correlation to TTE(r=0.89; p< 0.001). Bland-Al tman plot illustrated good intermodality agreement between the two methods(limit s of agreement, 0.20; 0.29). CONCLUSIONS: Multislice computed tomography may pro vide an accurate, noninvasive imaging technique for detection of patients with A S and quantification of AVA.展开更多
文摘OBJECTIVES: The purpose of this study was to evaluate whether multislice compu ted tomography(MSCT) provides a reliable, noninvasive imaging modality for ident ification of patients with degenerative aortic valve stenosis(AS) by quantifying the aortic valve area(AVA) in comparison to the accepted diagnostic standard tr ansthoracic echocardiography(TTE). BACKGROUND: Management of patients with degen erative AS is based on the severity of disease. The severity of AS in clinical p ractice is assessed by TTE and classified as mild, moderate, or severe according to the AVA. METHODS: Forty-six patients were examined with contrast-enhanced, electrocardiogram-gated, 16-row MSCT for the evaluation of the diagnostic acc uracy. In 30 patients, quantification of the AVA with MSCT was compared to TTE u sing the continuity equation with Doppler velocity-time integral for calculatio n of the AVA. RESULTS: Sensitivity of MSCT for the identification of patients wi th degenerative AS was 100%, and the specificity was 93.7%. Thirty of 46 patie nts had AS determined by TTE. Quantification of AVA by MSCT(mean AVA=0.94 cm2) i n patients with AS showed a good correlation to TTE(r=0.89; p< 0.001). Bland-Al tman plot illustrated good intermodality agreement between the two methods(limit s of agreement, 0.20; 0.29). CONCLUSIONS: Multislice computed tomography may pro vide an accurate, noninvasive imaging technique for detection of patients with A S and quantification of AVA.
