Objective： To observe the effect of electro-scalp acupuncture on glucose metabolism of cerebral regions involving mental activity in healthy people. Methods: A total of 6 cases of volunteer healthy subjects (3 males ...Objective： To observe the effect of electro-scalp acupuncture on glucose metabolism of cerebral regions involving mental activity in healthy people. Methods: A total of 6 cases of volunteer healthy subjects (3 males and 3 females) ranging in age from 22 to 36 years were subjected to this study. Changes of cerebral glucose metabolism before and after electro-scalp acupuncture were observed by using positron emission tomography (PET) and semi-quantifying analysis method. Electro-scalp acupuncture stimulation (50 Hz, 2 rnA) of Middle Line of Vertex (Dingzhongxian,顶中线,MS5), Middle Line of Forehead (Ezhongxian,额中线, MS1 ) and bilateral Lateral Line 1 of Forehead (Epangyixian,额旁一线,MS2) was administered for 30 minutes. Then cerebral regions of interest (ROIs) were chosen and their average glucose metabolism levels (radioactivity of 18 fluorine deoxyglucose ) were analyzed. Results：After administration of electro-scalp acupuncture, the glucose metabolism levels in bilateral frontal lobes and bilateral caudate nuclei, left cingulate gyrus and right cerebellum increased significantly in comparison with those of prestimulation (P<0.05). Conclusion: Electro-scalp acupuncture of MS1, MS2 and MS5 can increase the glucose metabolism of certain cerebral regions involving mental activity in healthy subjects.展开更多
基金Subsidized by National Nature Science Foundation of China(30100246)
文摘Objective： To observe the effect of electro-scalp acupuncture on glucose metabolism of cerebral regions involving mental activity in healthy people. Methods: A total of 6 cases of volunteer healthy subjects (3 males and 3 females) ranging in age from 22 to 36 years were subjected to this study. Changes of cerebral glucose metabolism before and after electro-scalp acupuncture were observed by using positron emission tomography (PET) and semi-quantifying analysis method. Electro-scalp acupuncture stimulation (50 Hz, 2 rnA) of Middle Line of Vertex (Dingzhongxian,顶中线,MS5), Middle Line of Forehead (Ezhongxian,额中线, MS1 ) and bilateral Lateral Line 1 of Forehead (Epangyixian,额旁一线,MS2) was administered for 30 minutes. Then cerebral regions of interest (ROIs) were chosen and their average glucose metabolism levels (radioactivity of 18 fluorine deoxyglucose ) were analyzed. Results：After administration of electro-scalp acupuncture, the glucose metabolism levels in bilateral frontal lobes and bilateral caudate nuclei, left cingulate gyrus and right cerebellum increased significantly in comparison with those of prestimulation (P<0.05). Conclusion: Electro-scalp acupuncture of MS1, MS2 and MS5 can increase the glucose metabolism of certain cerebral regions involving mental activity in healthy subjects.
