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Common stemness regulators of embryonic and cancer stem cells 被引量:6
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作者 Christiana Hadjimichael Konstantina Chanoumidou +3 位作者 Natalia Papadopoulou Panagiota Arampatzi Joseph Papamatheakis Androniki Kretsovali 《World Journal of Stem Cells》 SCIE CAS 2015年第9期1150-1184,共35页
Pluripotency of embryonic stem cells(ESCs) and induced pluripotent stem cells is regulated by a well characterized gene transcription circuitry. The circuitry is assembled by ESC specific transcription factors, signal... Pluripotency of embryonic stem cells(ESCs) and induced pluripotent stem cells is regulated by a well characterized gene transcription circuitry. The circuitry is assembled by ESC specific transcription factors, signal trans-ducing molecules and epigenetic regulators. Growing understanding of stem-like cells, albeit of more complex phenotypes, present in tumors(cancer stem cells), provides a common conceptual and research frame-work for basic and applied stem cell biology. In this review, we highlight current results on biomarkers, gene signatures, signaling pathways and epigenetic regulators that are common in embryonic and cancer stem cells. We discuss their role in determining the cell phenotype and finally, their potential use to design next generation biological and pharmaceutical approaches for regenerative medicine and cancer therapies. 展开更多
关键词 EMBRYONIC STEM CELLS Cancer STEM CELLS Pluripotenc
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Highly sensitive ozone and hydrogen sensors based on perovskite microcrystals directly grown on electrodes
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作者 Aikaterini Argyrou Konstantinos Brintakis +5 位作者 Athanasia Kostopoulou Emmanouil Gagaoudakis Ioanna Demeridou Vassilios Binas George Kiriakidis Emmanuel Stratakis 《Journal of Materiomics》 SCIE 2022年第2期446-453,共8页
Highly-sensitive and stable ozone and hydrogen sensing elements were fabricated based on well-crystalline rounded cube-shaped CsPbBr 3 microcrystals,synthesized by a facile solution process per-formed under ambient co... Highly-sensitive and stable ozone and hydrogen sensing elements were fabricated based on well-crystalline rounded cube-shaped CsPbBr 3 microcrystals,synthesized by a facile solution process per-formed under ambient conditions.It is shown that such elements demonstrate enhanced room tem-perature gas sensing ability compared to the previously reported metal halide and oxide-based ones.Electrical measurements performed on these sensing components revealed high sensitivity to ultra-low ozone and hydrogen concentrations,namely 4 ppb and 1 ppm respectively,as well as a remarkable repeatability,even after a few months of storage in ambient conditions.Both ozone and hydrogen sensors were self-activated,as they did not require the use of UV or heating external stimuli to operate,and exhibited fast detection and short restoration times.All such attractive properties along with the simple fabrication process could provide an easy,efficient and low-cost technology for the realization of future gas sensing devices. 展开更多
关键词 All-inorganic perovskite crystals Solution process Ozone sensing Hydrogen sensing High sensitivity Room-temperature sensor Perovskite sensors
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