AIM: To assess the efficacy and safety of patterned laser trabeculoplasty(PLT) as an adjunctive treatment in open angle glaucoma(OAG) or ocular hypertension(OHT) patients who were under antiglaucoma medical tre...AIM: To assess the efficacy and safety of patterned laser trabeculoplasty(PLT) as an adjunctive treatment in open angle glaucoma(OAG) or ocular hypertension(OHT) patients who were under antiglaucoma medical treatment.METHODS: This study was a retrospective review of primary or secondary OAG patients and OHT patients with medically uncontrolled(≥18 mm Hg) intraocular pressure(IOP) who underwent 360o PLT from June 2016 to August 2016. Follow-up visits at week 1, and 1, 3 and 6 mo were performed. IOP, best corrected visual acuity(BCVA), complications and eye drop glaucoma medication were recorded at each follow-up visit. Success was defined as IOP reduction ≥20% from baseline. RESULTS: Forty-one eyes of 25 patients were included in this study. Pre-treatment mean IOP was 20.2±1.6 mm Hg. After PLT, IOP was 19.3±5.2, 16.1±2.7, 17.1±3.7 and 16.3±3.5 mm Hg,at 1 wk, 1, 3 and 6 mo, respectively. IOP reduction from baseline was statistically significant from the first month, remaining stable at 6 mo(P〈0.001). PLT success at 6 mo of follow-up was 48.78%. The number of glaucoma medication per eye(P=0.10) and the mean BCVA both remained constant(P=0.37). Complications included transient IOP spikes in 4 eyes(9.8%) and peripheral anterior synechiae in 7 eyes(17.1%). CONCLUSION: PLT is an effective and safe method for the management of patients with OHT or OAG as an adjunctive therapy. Additional larger studies should be designed to verify the long-term stability of IOP reduction with this laser technology.展开更多
文摘AIM: To assess the efficacy and safety of patterned laser trabeculoplasty(PLT) as an adjunctive treatment in open angle glaucoma(OAG) or ocular hypertension(OHT) patients who were under antiglaucoma medical treatment.METHODS: This study was a retrospective review of primary or secondary OAG patients and OHT patients with medically uncontrolled(≥18 mm Hg) intraocular pressure(IOP) who underwent 360o PLT from June 2016 to August 2016. Follow-up visits at week 1, and 1, 3 and 6 mo were performed. IOP, best corrected visual acuity(BCVA), complications and eye drop glaucoma medication were recorded at each follow-up visit. Success was defined as IOP reduction ≥20% from baseline. RESULTS: Forty-one eyes of 25 patients were included in this study. Pre-treatment mean IOP was 20.2±1.6 mm Hg. After PLT, IOP was 19.3±5.2, 16.1±2.7, 17.1±3.7 and 16.3±3.5 mm Hg,at 1 wk, 1, 3 and 6 mo, respectively. IOP reduction from baseline was statistically significant from the first month, remaining stable at 6 mo(P〈0.001). PLT success at 6 mo of follow-up was 48.78%. The number of glaucoma medication per eye(P=0.10) and the mean BCVA both remained constant(P=0.37). Complications included transient IOP spikes in 4 eyes(9.8%) and peripheral anterior synechiae in 7 eyes(17.1%). CONCLUSION: PLT is an effective and safe method for the management of patients with OHT or OAG as an adjunctive therapy. Additional larger studies should be designed to verify the long-term stability of IOP reduction with this laser technology.