Spatio-temporal Evolution Characteristics and Driving Forces of Winter Urban Heat Island:A Case Study of Rapid Urbanization Area of Fuzhou City,China

Under the influence of anthropogenic and climate change,the problems caused by urban heat island(UHI)has become increasingly prominent.In order to promote urban sustainable development and improve the quality of human settlements,it is significant for exploring the evolution characteristics of urban thermal environment and analyzing its driving forces.Taking the Landsat series images as the basic data sources,the winter land surface temperature(LST)of the rapid urbanization area of Fuzhou City in China was quantitatively retrieved from 2001 to 2021.Combing comprehensively the standard deviation ellipse model,profile analysis and GeoDetector model,the spatio-temporal evolution characteristics and influencing factors of the winter urban thermal environment were systematically analyzed.The results showed that the winter LST presented an increasing trend in the study area during 2001–2021,and the winter LST of the central urban regions was significantly higher than the suburbs.There was a strong UHI effect from 2001 to 2021with an expansion trend from the central urban regions to the suburbs and coastal areas in space scale.The LST of green lands and wetlands are significantly lower than croplands,artificial surface and unvegetated lands.Vegetation and water bodies had a significant mitigation effect on UHI,especially in the micro-scale.The winter UHI had been jointly driven by the underlying surface and socio-economic factors in a nonlinear or two-factor interactive enhancement mode,and socio-economic factors had played a leading role.This research could provide data support and decision-making references for rationally planning urban layout and promoting sustainable urban development.

Spatiotemporal Evolution of Urban Heat Islands and Optimization of Spatial Network Construction in the Central Urban Area of Fuzhou City, China

Although accelerated urbanization has led to economic prosperity,it has also resulted in urban heat island effects.Therefore,identifying methods of using limited urban spaces to alleviate heat islands has become an urgent issue.In this study,we assessed the spatiotemporal evolution of urban heat islands within the central urban area of Fuzhou City,China from 2010 to 2019.This assessment was based on a morphological spatial pattern analysis(MSPA)model and an urban thermal environment spatial network constructed us-ing the minimum cumulative resistance(MCR)model.Optimization measures for the spatial network were proposed to provide a theor-etical basis for alleviating urban heat islands.The results show that the heat island area within the study area gradually increased while that of urban cold island area gradually decreased.The core area was the largest of the urban heat island patch landscape elements with a significant impact on other landscape elements,and represented an important factor underlying urban heat island network stability.The thermal environment network revealed a total of 197 thermal environment corridors and 93 heat island sources.These locations were then optimized according to the current land use,which maximized the potential of 1599.83 ha.Optimization based on current land use led to an increase in climate resilience,with effective measures showing reduction in thermal environment spatial network structure and function,contributing to the mitigation of urban heat island.These findings support the use of current land use patterns during urban heat island mitigation measure planning,thus providing an important reference basis for alleviating urban heat island effects.

A Distinguishing Method and Distribution Characteristics of Fog and Haze Days in Fuzhou

For data of atmospheric composition missing, fog and haze days were distinguished based on the standard of meteorological industry Observation and Forecasting Levels of Haze （QX/T113-2010） and four user-defined standards, and using data of surface meteorological factors in Fuzhou City, China from 2005 to 2011, temporal distributions of fog and haze days were analyzed respectively to provide methods for fog and haze forecast. The results showed that there were 28.9 fog days and 89.7 haze days per year in Fuzhou. Both fog and haze days were variable, and there might be a day difference of twice to thrice among the years. They were the most in 2007, and then decreased in recent years. Both fog and haze days were more in winter and spring, accounted for 94.1% and 70.1% respectively, while in summer and autumn, they only accounted for 5.9% and 29.9% respectively. In a day, fog mainly occurred from night to early morning, while haze occurred mainly at about noon, which demonstrated that fog and haze are different synoptic phenomena. The mass concentration of PM2.5 in fog days was 34 μg/m^3, while it was 61 μg/m^3 in haze days, and in 22% of haze days it was larger than 75 μg/m3, which was above the national second-grade ambient air quality standard.

Evaluation and Analysis of Nutrients in Tobacco-Planting Soil in Fuzhou City

[Objective] The aim was to explore the nutrient status of tobacco-planting soil, and find out the fertilization strategy for flue-cured tobacco. [Method] The nutrient contents in 142 soil samples from 7 tobacco planting counties in Fu Zhou city were determined and evaluated. [Result] The organic matter content was on the high side, and most soil was acid soil. The soil had abundant total nitrogen, total phosphorus and total potassium, moderate available nitrogen and available phosphorus, low available potassium, high water soluble chlorine, low soil cation exchange capacity and rich effective zinc, but effective boron was famine. [Conclusion] The meta-acid soil should be conducted with pH adjustment, and rational nitrogen, phosphorus and potassium application.

Active Fault Exploration and Seismic Hazard Assessment in Fuzhou City

It has been proven by a number of earthquake case studies that an active fault-induced earthquake beneath a city can be devastating. It is an urgent issue for seismic hazard reduction to explore the distribution of active faults beneath the urban area and identify the seismic source and the risks underneath. As a pilot project of active fault exploration in China, the project, entitled “Active fault exploration and seismic hazard assessment in Fuzhou City”, started in early 2001 and passed the check before acceptance of China Earthquake Administration in August 2004. The project was aimed to solve a series of scientific issues such as fault location, dating, movement nature, deep settings, seismic risk and hazard, preparedness of earthquake prevention and disaster reduction, and etc. by means of exploration and assessment of active faults by stages, i.e., the preliminary survey and identification of active faults in target area, the exploration of deep seismotectonic settings, the risk evaluation of active seismogenic faults, the construction of geographic information system of active faults, and so on. A lot of exploration methods were employed in the project such as the detection of absorbed mercury, free mercury and radon in soil, the geological radar, multi-channel DC electrical method, tsansient electromagnetic method, shallow seismic refraction and reflection, effect contrast of explored sources, and various sounding experiments, to establish the buried Quaternary standard section of the Fuzhou basin. By summing up, the above explorations and experiments have achieved the following results and conclusions ：

A Study on the Translation of Public Signs in Fuzhou

Public signs, as a city's "name card", have attracted wide attention. However,inappropriate translation of public signs are ubiquitous with some even cause misunderstandings for international visitors. In this paper, we first introduce the function of public signs, then through case analysis many problems are exposed and those errors bring a lot of inconvenience for foreigners who live and work in China.What's worse, to some extent, China's image and reputation will also be undermined.Finally, an appeal is made for a standardized translation of public signs and more research should be done and effective measures should be taken to improve the quality of the language environment and public signs translation.

Division of Buried Late Quaternary Strata of the Fuzhou Basin

Based on detailed logging of fourteen drill holes, combined with the results of other researchers, the preliminary summarization on sedimentary characteristics of the late Pleistocene of the Fuzhou basin is done. The deposition of Fuzhou basin began from about 56.5ka BP and the sediments are composed of gravel, sand, clay and silt, which show a depositional sequence with granularity becoming smaller from the lower to the upper and a big lateral variation of lithology. There are three silt layers in late Quaternary strata of Fuzhou basin. The first and second layers were developed during the middle and late Holocene, the deposition time is about 7.86ka BP to 1.44 ka BP and they are the results of ＂Changle Transgression＂. The third was developed during the late of late Pleistocene and the deposition time is from 44ka BP to 20ka BP and it is the result of ＂Fuzhou Transgression＂. The buried late Quaternary sediments in Fuzhou basin can be divided into upper Pleistocene series and Holocene series, which include four formations from old to new. They are the Longhai formation （ Q3p 1）, Dongshan formation （Qhd）, Changle formation （Qhc） and Jiangtian formation （Qhj）, respectively. The Longhai formation can be divided into three members and belongs to the Pleistocene series, other three formations belong to the Holocene series.

Urban Expansion and Its Influencing Factors in Natural Wetland Distribution Area in Fuzhou City,China

This paper principally focuses on land use dynamics,urban expansion and underlying driving forces in the Natural Wetland Distribution Area(NWDA)of Fuzhou City in the southeastern China.Based on time series Landsat TM/ETM+imageries and historical data,relationships between urban land expansion and its influencing factors from 1989 to 2009 were analyzed by using an integrated approach of remote sensing(RS)and geographic information system(GIS)techniques.The results showed that built-up land increased from 151.16 km2in 1989 to 383.76 km 2in 2009. Approximately 64.25%of the newly emerging built-up land was converted from cropland(29.47%),forest and shrub (25.78%),water(3.73%),wetland(4.61%),and bare land(0.66%)during 1989 and 2009.With a remarkable decrease in cropland,the proportion of non-agricultural population increased by 23.6%.Moreover,rapid development of infrastructures,facilities,industrial parks,and urban and rural settlements along the Minjiang River resulted in the eastward and southward expansion of built-up land.Additionally,the growth pattern of built-up land in the NWDA is highly correlated with socio-economic factors,including the gross domestic product(GDP),GDP per capita,and structure of industry.As a result,the observed environmental degradation such as loss of cropland and wetland due to heavy pressure of rapid urbanization have greatly impaired the carrying capacity of city.Thus,in addition to scientific and rational policies towards minimizing the adverse effects of urbanization,coordination between the administrative agencies should be urgently strengthened to balance the conflicts between urban development and ecological conservation to make sure the sustainable land use.

Detection and Analysis of Number of Ralstonia solanacearum in Soil before Winter Tillage in Fuzhou Tobacco-growing Area, Jiangxi Province

[Objective]The paper was to optimize the tobacco planting area in Fuzhou City and to prevent the outbreak of tobacco bacterial wilt in large area.[Method]At the end of 2017,soil samples were collected from plots planned to be planted with tobacco in the following year in Yihuang,Guangchang,Lichuan and Le’an counties.[Result]Among 352 plots,116 plots were infected by Ralstonia solanacearum,while 236 plots were free of the pathogen,and the infected plots accounted for 32.95% of total plots.Among them,75 plots exceeded the order of magnitudes of 103,accounting for 21.31% of total plots and 64.66% of infected plots.It is suggested that the plots with an order of magnitude above 103 should be pretreated with quicklime or purple soil,or conducted crop rotation,or seeds must be directly abandoned;the dosage of biocontrol agents should be increased in planting.The plots with an order of magnitude below 103 should be pretreated with quicklime or purple soil,and the dosage of biocontrol agents should be increased in planting.[Conclusion]The results provide reliable theoretical basis and data support for soil improvement and bacterial wilt control.

Compilation of Control Guidelines for the Skyline along the Minjiang River(Fuzhou Section)

Minjiang River is the mother river of Fuzhou.The skyline views on both sides of the Minjiang River directly refl ect the characteristics of Fuzhou’s urban style.Compiling guidelines for the control of the skyline along the Minjiang River will provide guidance measures for optimizing and enhancing the skyline landscape along the Minjiang River.From the fi ve elements of rhythm,permeability,visual centrality,sense of mountain display and layering,evaluation criteria are established for the skyline along the Minjiang River,and targeted guidance and optimization measures are constructed.

Revitalization Strategy in Conservation and Renewal of Historical and Cultural Districts:A Case Study of Shangxiahang in Fuzhou City

Taking the revitalization strategy in conservation and renewal of Shangxiahang historical and cultural district as an example,the paper analyzes the main problems at the present stage and the main contradictions with urban development,and puts forward the revitalization practice for conservation and renewal of Shangxiahang historical district by using related revitalization theory and planning principles.Furthermore,the contemporary practicality of Shangxiahang district is increased on the basis of protection,giving play to its contemporary charm.

Research on the Application and Public Experience of Green Landscape Color Art in Fuzhou

In the landscape design, the green landscape is an indispensable landscape element, and the plant color is an important factor affecting the green landscape. The color matching and layout are inseparable from the research on color art. Color art not only affects our vision, but also influences people's psychology and behavior through vision. In the following, Fuzhou will be used as an example to analyze the application of color art in the green landscape and the public experience.

Exploring the spatiotemporal relationship between green infrastructure and urban heat island under multi‐source remote sensing imagery:A case study of Fuzhou City

Green Infrastructure(GI)has garnered increasing attention from various regions due to its potential to mitigate urban heat island(UHI),which has been exacerbated by global climate change.This study focuses on the central area of Fuzhou city,one of the“furnace”cities,and aims to explore the correlation between the GI pattern and land surface temperature(LST)in the spring and autumn seasons.The research adopts a multiscale approach,starting from the urban scale and using urban geographic spatial characteristics,multispectral remote sensing data,and morphological spatial pattern analysis(MSPA).Significant MSPA elements were tested and combined with LST to conduct a geographic weighted regression(GWR)experiment.The findings reveal that the UHI in the central area of Fuzhou city has a spatial characteristic of“high temperature in the middle and low temperature around,”which is coupled with a“central scattered and peripheral concentrated”distribution of GI.This suggests that remote sensing data can effectively be utilised for UHI inversion.Additionally,the study finds that the complexity of GI,whether from the perspective of the overall GI pattern or the classification study based on the proportion of the core area,has an impact on the alleviation of UHI in both seasons.In conclusion,this study underscores the importance of a reasonable layout of urban green infrastructure for mitigating UHI.

An SEIHR model with age group and social contact for analysis of Fuzhou COVID-19 large wave

The main epidemiological features such as basic reproduction number,effective reproduction number and sensitivity analysis were extensively discussed for multi-age groups SEIHR model in this study.Firstly,by using of the next generation matrix method,basic reproduction number R0 of the total population was estimated as 1.57 using parameter values of four age groups of Fuzhou COVID-19 large wave.Given age group k,the values of R_(0k)(age group k to age group k),the values of R_(o)^(k)(an infected of age group k to the total population)and the values of R_(o)^(k)>R_(0k)>R_(o)^(k)(an infected of the total population to age group k)were also estimated,in which the explorations of the impacts of age groups revealed that the relationship was valid.Then,the fluctuating tendencies of effective reproduction number Rt were demonstrated by using two approaches(the surveillance data and the SEIHR model)for Fuzhou COVID-19 large wave,during which high-risk group(G4 group)mainly contributed the infection scale due to high susceptibility to infection and high risks to basic diseases.Further,the sensitivity analysis using two approaches(the sensitivity index and the PRCC values)revealed that susceptibility to infection of age groups played the vital roles,while the numerical simulation showed that infection scale varied with the changes of social contacts of age groups.The results of this study claimed that the high-risk group out of the total population was concerned by the local government with the highest susceptibility to infection against COVID-19.Conclusions This study verified that the partition structure of age groups of the total population,the susceptibility to infection of age groups,the social contacts among age groups were the important contributors of infection scale.The less social contacts and adequate hospital beds for high-risk group were profitable to control the spread of COVID-19.To avoid the emergence of medical runs against new variant in the future,the policymakers from local government were suggested to decline social contacts when hospital beds were limited.

成熟度和温度对芙蓉李贮藏期间生理生化特性及蜡质结构的影响

为研究成熟度和温度对芙蓉李贮藏期间生理生化特性和果皮蜡质结构的影响,本研究选择2个成熟度(F:约六成熟;S:约八成熟)的芙蓉李,于4、25℃条件下进行试验,分析16个生理生化指标的差异,采用正交偏最小二乘判别法(OPLS-DA)筛选不同成熟度芙蓉李在不同温度贮藏期间的主要差异性指标,检测芙蓉李贮藏前后蜡质结构的变化并分析其贮藏效应。结果表明,4℃条件下F与S之间的主要差异性指标为可溶性固形物含量(SS)、果肉硬度(FF)、果皮色度值a^(*)(PC-a^(*))、花色苷(AC)含量、可滴定酸(TA)含量、果皮硬度(PF),25℃时为SS、超氧化物歧化酶(SOD)活性、PC-a^(*)、果皮色度值b*(PC-b*)。不同成熟度果实的SS含量、PC-a^(*)、AC含量均随贮藏天数增加而逐渐上升(S贮藏28 d除外),同一贮藏天数下AC含量在25℃时显著高于4℃时,同一温度同一贮藏天数时S中的SS含量、PC-a^(*)显著高于F;PF、FF和TA含量随贮藏天数的延长而逐渐下降,4℃和F有利于FF和PF的保持,而25℃下TA含量下降更快;SOD活性随贮藏天数的延长先升高后下降,且在25℃和S中下降更显著。芙蓉李蜡质主要以直立片状晶体和颗粒状结晶的形式存在;两种晶体数量和形态的变化可能影响水分的流失,从而影响细胞壁结构的稳定性,进而影响贮藏性。本研究可为芙蓉李的采收和贮藏保鲜提供技术参考。

基于临床基线特征与颈动脉超声参数构建脑卒中高危人群颈动脉易损斑块模型

背景:研究表明,颈动脉斑块的易损性和弹性与斑块内新生血管的存在及形成程度有关。超声作为筛查和评价颈动脉易损斑块的首选检查手段,具有无创、操作便捷、可重复性高和无辐射等的特点。目的:基于临床基线特征与颈动脉超声参数,探讨脑卒中高危人群颈动脉易损斑块的影响因素,基于独立危险因素构建并验证风险列线图(Nomogram)预测模型。方法:回顾性选取2021年11月到2023年11月于抚州市第一人民医院行脑卒中筛查确定为脑卒中高危人群的180例患者作为研究对象,将180例患者按7∶3比例分为建模集(n=126)和验证集(n=54),根据颈动脉超声检查结果将建模集研究对象分为易损斑块组(n=54)和非易损斑块组(n=72)。通过多因素Logistic回归得出独立危险因素,构建Nomogram模型,并使用R语言绘制决策曲线以评估模型的临床效益。采用受试者工作特征曲线和校准曲线检验模型的预测效能,同时分析验证集的病例数据进行外部验证。结果与结论:①多因素Logistic回归结果显示,年龄、脑卒中家族史、颈动脉斑块最大厚度值、颈动脉斑块数量、尿微量白蛋白和尿微量白蛋白/肌酐均与脑卒中高危人群颈动脉易损斑块有关(P<0.05)。②构建的Nomogram模型受试者工作特征曲线下面积为0.917,灵敏度和特异度分别为79.6%和91.7%;决策曲线结果显示,该模型的潜在临床获益可观,可用性较高;校准曲线结果提示,模型具备较好的预测准确性;验证集结果显示,模型的外部预测性能良好。③结果说明,脑卒中高危人群颈动脉易损斑块受年龄、脑卒中家族史、颈动脉斑块最大厚度值等因素影响,基于各独立危险因素构建的风险Nomogram预测模型的预测性能良好,可为临床上治疗此类高危人群提供有力的参考依据。

超声引导下针刀松解黄韧带对兔退变腰椎间盘整合素α5、β1表达的影响

背景:针刀松解黄韧带可有效改善腰椎退行性患者的症状,超声引导可增加针刀松解的精准性,但针刀松解黄韧带后对退变椎间盘的具体影响及可能的机制尚待明确。目的:探讨超声引导下针刀松解黄韧带对兔腰椎间盘退变的作用。方法:取24只新西兰兔,采用随机数字表法分为对照组(n=6)与造模组(n=18)。造模组采用横断L5/6、L6/7节段棘上、棘间韧带并保持站立姿势对腰椎施加轴向载荷的方式建立兔腰椎间盘退变模型,造模成功后再随机分为模型组、超声针刀组、假针刀组,每组6只,超声针刀组在超声引导下使用针刀松解L7/S1右侧黄韧带,假针刀组针刀入路同超声针刀组,但不松解黄韧带,1次/周,共4次。针刀干预后30 d,利用MRI观察L7/S1椎间盘髓核信号强度变化,苏木精-伊红染色观察L7/S1椎间盘形态变化,免疫组化染色检测L7/S1椎间盘髓核内Ⅰ,Ⅱ型胶原表达,RT-PCR、Western Blot检测L7/S1椎间盘中整合素α5、β1、p38、核因子κB的表达。结果与结论:①MRI成像显示,模型组兔椎间盘髓核呈灰-黑色,髓核灰度值明显低于对照组(P<0.01);超声针刀组兔椎间盘髓核亮度较模型组升高,髓核灰度值高于模型组(P<0.01);②苏木精-伊红染色显示,模型组髓核形状不规则,髓核细胞数量减少,细胞外基质被压缩,纤维环破裂,终板结构与边界不清,软骨细胞排列紊乱;与模型组相比,超声针刀组髓核细胞数量增多,纤维环破裂情况有改善,软骨终板细胞排列较为规则;③免疫组化染色显示,与对照组比较,模型组髓核内Ⅰ型胶原阳性表达增加(P<0.01),Ⅱ型胶原阳性表达减少(P<0.01);与模型组比较,超声针刀组髓核内Ⅰ型胶原阳性表达减少(P<0.01),Ⅱ型胶原阳性表达增加(P<0.01);④RT-PCR、Western Blot检测显示,与对照组比较,模型组兔椎间盘中整合素α5、整合素β1、p38、核因子κB的mRNA与蛋白表达均升高(P<0.01);与模型组比较,超声针刀组兔椎间盘中整合素α5、整合素β1、p38、核因子κB的mRNA与蛋白表达均降低(P<0.01);⑤结果表明,超声引导下针刀松解黄韧带可改善兔腰椎间盘退变程度,该作用与通过调控整合素α5、β1表达、抑制p38和核因子κB表达有关。

特发性脊柱侧弯患者步行生物力学特征:三维运动捕捉的横断面分析

背景:脊柱侧弯的生物力学分析病例数量有限,仅限于对脊柱或下肢独立进行生物力学分析,缺乏对人体多维度整体的评估,难以反映躯干与下肢在日常活动中的运动关系,不利于综合指导临床治疗。目的:通过测量脊柱侧弯患者在步行活动中的脊柱运动学,研究脊柱不同节段及下肢运动学/动力学在步态活动中的关系,以全方位多层次评估脊柱侧弯患者与正常人群在生物力学的差异,为临床防治脊柱侧弯提供循证依据。方法:此研究为一项横断面研究,于2020年7月至2021年6月,在福州大学城、福建中医药大学附属康复医院纳入脊柱侧弯患者28例及同年龄段正常人28例。采用三维运动捕捉系统以100 Hz的采样频率捕捉步态的运动学数据,2块测力台(AMTI 400600,采样频率1500 Hz)嵌于长10 m(数据采集有效长度为4 m),宽2.4 m平地走道采集动力学数据。比较两组受试者执行平地步行时步态时空参数,运动学及动力学参数的差异。所有受试者在纳入后立即接受全脊柱X射线片测量比较两组差异。结果与结论:(1)脊柱侧弯患者肩胛带-躯干相对旋转活动度、胸廓-骨盆相对旋转活动度较正常组小(P<0.05),骨盆旋转活动度相较正常组大(P<0.05)。(2)脊柱侧弯患者髋、膝关节屈伸活动度,髋关节凹凸侧屈伸峰力矩、地反力凸侧内外向峰值较正常组小(P<0.05)。(3)脊柱侧弯患者的膝关节屈伸活动度非对称性指数、肩胛带-躯干相对旋转活动度非对称性指数、胸廓-骨盆相对旋转活动度非对称性指数较正常组大(P<0.05)。(4)上述结果证实,脊柱侧弯患者在平地行走时肩胛带-胸廓-骨盆之间僵硬的运动模式,髋膝关节屈伸活动度减少,髋关节双侧屈伸力矩峰值及地反力凸侧内外向峰值降低。这些特征可以作为康复评估及治疗方案制定的依据。

“双碳”背景下福州市能源足迹趋势分析及预测

基于生态足迹和碳足迹理论,提出能源足迹的概念与计算方法。以福州市为例,分别按能源种类和工业行业计算了该市2011-2020年能源足迹及其强度,对这10年能源足迹变化趋势做了分析,运用STIRPAT模型及岭回归分析方法进行了预测,并按照高速和基准两个情景对能源足迹分别进行了分析和预测。研究表明,福州市2011-2020年能源足迹呈现波动下降又回升趋势,能源足迹强度则整体呈现下降趋势,能源结构不断优化;福州市要实现2030年碳达峰情景,能源足迹强度每年需降低4.1062%(按研究期的水平)。福州市应继续坚持生态城市和数字城市的发展目标,从能源种类上看应该大力发展风能、水利、天然气、太阳能、核电等可再生能源;从工业结构上则要做强计算机、通信和其他电子设备制造业。本研究对于城市产业结构优化、碳排放目标实现均有一定的理论参考价值和现实意义。

超声引导针刀松解椎间孔内口对兔软骨终板基质稳态的影响

背景:软骨终板基质稳态与椎间盘退变关系密切,针刀松解椎间孔内口后壁黄韧带可改善腰椎间盘退变患者的症状,其作用机制是否与调控软骨终板基质稳态有关尚待明确。目的:探讨超声引导下针刀松解兔L_(7)/S_(1)椎间孔内口对软骨终板基质稳态的影响。方法:24只雄性新西兰兔随机分为对照组6只、造模组18只,采用横断棘上棘间韧带后间歇性站立的方式进行腰椎间盘退变造模,时间为12周。造模后将造模组随机分为模型组、针刀组、假针刀组,每组6只。针刀组在超声引导下针刀松解兔L_(7)/S_(1)右侧椎间孔内口后壁黄韧带,假针刀组针刀只抵达椎间孔内口后壁黄韧带表面,共干预4次,每次间隔1周;对照组、模型组兔不做干预。干预结束30 d后,MRI观察椎间盘退变情况;苏木精-伊红染色、番红O固绿染色观察L_(7)/S_(1)椎间盘软骨终板、髓核、纤维环形态并评分;免疫组化检测L_(7)/S_(1)椎间盘髓核、软骨终板Ⅱ型胶原、蛋白聚糖、基质金属蛋白酶13表达。结果与结论:①MRI显示,L_(7)/S_(1)髓核相对灰度值模型组明显低于对照组(P<0.01),针刀组高于模型组和假针刀组(P<0.05);②苏木精-伊红染色及番红O固绿染色显示,模型组髓核、纤维环退变明显,软骨终板变薄,与骨性终板交界处钙化明显,针刀组软骨终板形态及髓核退变较模型组改善;模型组、针刀组、假针刀组形态学评分明显高于对照组(P<0.01);针刀组评分明显低于模型组和假针刀组(P<0.01);③免疫组化显示,与对照组比较,模型组和假针刀组髓核、软骨终板中Ⅱ型胶原、蛋白聚糖表达明显降低(P<0.01),基质金属蛋白酶13表达明显升高(P<0.01);与模型组、假针刀组比较,针刀组髓核、软骨终板Ⅱ型胶原、蛋白聚糖表达升高(P<0.05),基质金属蛋白酶13表达明显降低(P<0.01);④结论:针刀松解椎间孔内口可调节兔软骨终板基质稳态,改善椎间盘退变。