期刊文献+
共找到18篇文章
< 1 >
每页显示 20 50 100
Distribution of Atmospheric Pollution in Southern Benin
1
作者 Dossou-Gbete Sèdami Codjo Joël Kpadonou Dominique +5 位作者 Gbaguidi An Magloire Elegbede Vitalique Saizonou Kpèssou Virtus Mickael Youssao Abdou Karim Alassane Dovonon Firmin Léonce Vodounnon Armand 《Open Journal of Air Pollution》 2024年第1期23-55,共33页
This study focuses on air quality in southern Benin in order to show public authorities what the Beninese populations are exposed to for efficient decision-making. Two sampling campaigns were carried out, one in the w... This study focuses on air quality in southern Benin in order to show public authorities what the Beninese populations are exposed to for efficient decision-making. Two sampling campaigns were carried out, one in the wet period and the other in the dry season. The measurements were taken using a monitor called an “Air Quality Monitor”. For data processing, the multiple comparison methods of Dun (1961) and the Wilcoxon test were used. To maintain legitimacy, all spatial data were included in the official cartographic repository of Benin: WGS 1984, Transverse Mercator Universe Projection (UTM), Zone 31 North. The Moran statistic was used to measure the levels of spatial autocorrelation of the variables studied and to test the significance. In order to locate the spatial subsets, the local spatial association indices of Anselin Local Moran and Getis-Ord, Gi* were used. In terms of results, on the 13 monitoring sites and the 8 parameters chosen to determine air quality, we do not note any significant inter-seasonal difference. Of the eight parameters, only three parameters present spatial autocorrelation leading to predictions of ambient air quality over the entire study area based on the distance separating the points, namely, PM<sub>2.5</sub>, PM<sub>10</sub> and ambient air quality index (AQI). The localities affected by atmospheric pollution in South Benin are located in the south-western part of Benin, headed by Cotonou, which is heavily polluted by CO<sub>2</sub>, TCOV, PM<sub>10</sub> and PM<sub>2.5</sub>. 展开更多
关键词 Spatial Distribution Atmospheric Pollutants Southern Benin
下载PDF
Chemical Characterization of Lake Togbadji
2
作者 Vitalique Elegbede Dominique Kpadonou +2 位作者 Joël Dossou-Gbete Magloire Acakpo Nonvignon Gbaguidi Bienvenu Olatundji Ogoudele 《Journal of Water Resource and Protection》 2023年第12期721-753,共33页
The present study focused on the chemical characterization of the watercourse of the Togbadji Lake wildlife ranch. The methodological approach followed is as follows: Bibliography review, Sampling campaign. The result... The present study focused on the chemical characterization of the watercourse of the Togbadji Lake wildlife ranch. The methodological approach followed is as follows: Bibliography review, Sampling campaign. The results obtained were the subject of descriptive statistics, the two-sample Wilcoxon test to determine the impact of different localities on the abundance of microbiological contaminants, a Principal Component Analysis (PCA) with the software R version 3.5.0, in order to group the pollution parameters according to the different levels and sources of contamination. From our results, it is found that the respective average values in dry and rainy seasons for ammonium ions are 0.38 ± 0.16 mg/L and 0.22 ± 0.03 mg/L;for nitrite ions 0.20 ± 0.25 mg/L and 0.02 ± 0.01 mg/L;for nitrate ions 3.72 ± 2.52 mg/L and 7.84 ± 4.91 mg/L;for total Kjeldahl nitrogen 1.27 ± 1.44 mg/L and 1.19 ± 1.49 mg/L;for orthophosphate ions 0.20 ± 0.25 mg/L and 0.02 ± 0.01 mg/L;for total phosphorus 0.04 ± 0.01 mg/L and 0.11 ± 0.23 mg/L;the chemical oxygen demand 93.36 ± 61.73 mg/L of O2 and 89.93 ± 66.11 mg/L of O2 and the biochemical oxygen demand over 5 days 25.50 ± 18.22 mg/L of O2 and 37 ± 33.15 of O2. It emerged that the main sources of pollution in Lake Togbadji are runoff water, discharges of various wastewater from artisanal activities, livestock farming and open defecation. 展开更多
关键词 Chemical Degradation Aquatic Environment Lake Togbadji
下载PDF
Level of Exposure of Populations to Atmospheric Pollution in Southern Benin
3
作者 Sèdami Codjo Joël Dossou-Gbete Dominique Kpadonou +4 位作者 Gbaguidi Magloire Acakpo Nonvignon Vitalique Elegbede Alassane Youssao Abdou Karim Kpessou Virtus Mickael Saizonou Firmin Léonce Dovonon 《Open Journal of Air Pollution》 2023年第4期160-181,共22页
This study focuses on monitoring the exposure of populations in South Benin to atmospheric pollution. Thirteen (13) monitoring points were identified where the Air quality measurements were taken using autonomous elec... This study focuses on monitoring the exposure of populations in South Benin to atmospheric pollution. Thirteen (13) monitoring points were identified where the Air quality measurements were taken using autonomous electronic devices called “Air Quality Monitor”. Calibrated and turned on, the measuring device automatically determines the concentrations of carbon dioxide CO<sub>2</sub>, Total Organic Compounds, methanal (HCHO), particulate matter PM<sub>2.5</sub> and PM<sub>10</sub>, temperature in degrees Fahrenheit and relative humidity (RH). Per site, air pollution levels are recorded for 5 minutes every 30 minutes from 7 a.m. to 6 p.m. After the analyses, it appears that the carbon dioxide CO<sub>2</sub> contents vary from 400 to 1444 ppm with an average of 486.80 ± 184.3 ppm, the daily contents of Total Volatile Organic Compounds from 0.01 to 6 .91 mg/m<sup>3</sup> with a daily average of 0.36 ± 0.65 mg/m<sup>3</sup>, aldehydes from 0.005 to 3 mg/m<sup>3</sup> with an average of 0.05 ± 0.17 mg/m<sup>3</sup>, for particulate matter of diameters less than or equal to 2.5 μm (PM<sub>2.5</sub>) pollution levels vary between 5 and 173.8 μg/m<sup>3</sup> with an average of 21.5 ± 17.62 μg/m<sup>3</sup>. On the other hand, for PM<sub>10</sub>, the contents vary from 5 to 449.6 μg/m<sup>3</sup> with an average of 28.17 ± 31.74 μg/m<sup>3</sup>, the Air Quality Index (AQI) varies from 0, 3 to 243 with an average of 39 ± 33.16. From the results observed, it appears that the south-western part of South Benin is heavily polluted by CO<sub>2</sub>, Total Volatile Organic Compounds, PM<sub>10</sub> and especially PM<sub>2.5</sub> with the city of Cotonou at its head, in particular the Red Star crossroads, the Toyota crossroads and the crossroads after the friendship stadium. The impacts of this pollution could be significant on sensitive people such as the elderly, newborns and patients with acute and chronic respiratory illnesses. 展开更多
关键词 Ambient Air Quality Southern Benin Cotonou Atmospheric Pollution
下载PDF
传感器驱动的智能选矿:过去、现在和未来 被引量:9
4
作者 吴西顺 邓杰 +4 位作者 姜焕琴 姚翔 张炜 田黔宁 《矿产综合利用》 CAS 北大核心 2020年第5期18-26,共9页
基于传感器、大数据、AI的智能选矿,是建设现代智慧矿山的重要组成部分。传感器驱动的智能选矿,本质是数据驱动。选矿的自动化起步较早,但智能化滞后于其他行业,主要原因在于对传感器重视不够。几十年的矿业应用经验和发展趋势显示其自... 基于传感器、大数据、AI的智能选矿,是建设现代智慧矿山的重要组成部分。传感器驱动的智能选矿,本质是数据驱动。选矿的自动化起步较早,但智能化滞后于其他行业,主要原因在于对传感器重视不够。几十年的矿业应用经验和发展趋势显示其自动化程度不断提高,光选正在逐渐汇集成一大类智能感知与识别技术。颠覆性技术创新正重塑矿业新流程;高通量颗粒分拣从XRF、激光、近红外、色彩和XRT等多样化光源发展汲取能量;中子激活分析(PGNAA)、磁共振(MR)等传感技术的进步开创使块状拣选成为一项新兴领域;先进过程控制等数字化管理技术在研磨和浮选领域大显身手;CPR回收推动下游尾矿管理创新及综合利用从而实现可持续性发展。行业实践上,国际灯塔项目为智能选矿的发展提供了实际案例及宝贵经验。 展开更多
关键词 智能选矿 传感器 块状拣选 颗粒分选 颠覆性创新
下载PDF
GC~9A气相色谱仪的安装、调试和验收
5
《中氮肥》 1989年第2期140-145,149,共7页
GC9A是日本岛津公司八十年代的产品。该仪器的信息处理微机化,操作键盘化,是一种高精度、多功能的气相色谱仪。仪器涉及化学、物理、机械、电子技术、计算机技术等相关科学,属大型精密仪器,在我国有较多的用户。仪器开机、调试投运,
关键词 GC-9A 气相色谱仪 调试 安装
下载PDF
应用固态去耦合器减缓交流干扰的效果评价 被引量:4
6
作者 宋晓琴 王文强 +1 位作者 蓝卫 徐承伟 《腐蚀与防护》 北大核心 2017年第11期885-888,共4页
受高压交流输电线路接地极影响,三层聚乙烯防腐蚀层(3LPE)管道容易受到较强的交流干扰,通常采取"固态去耦合器+接地极"的减缓措施。通过对交流减缓效果、阴极保护效果、排流影响范围、直流漏流量等现场参数进行测试,全面介绍... 受高压交流输电线路接地极影响,三层聚乙烯防腐蚀层(3LPE)管道容易受到较强的交流干扰,通常采取"固态去耦合器+接地极"的减缓措施。通过对交流减缓效果、阴极保护效果、排流影响范围、直流漏流量等现场参数进行测试,全面介绍了一种固态去耦合器性能评价方案,并指出现有固态去耦合器在使用过程中存在过度设计及故障电流下铜接地极易出现电偶腐蚀等风险。 展开更多
关键词 固态去耦合器 交流减缓 接地极 阴极保护
下载PDF
Geology of Northern Sulaiman Foldbelt, Shirani and Waziristan Regions (South Punjab, Balochistan and Khyber Pakhtunkhwa): New Tomistominae (Miocene False Gharial) from Sakhi Sarwar Area of Dera Ghazi Khan (South Punjab), Pakistan 被引量:1
7
作者 Muhammad Sadiq Malkani Muhammad Ilyas +7 位作者 Riffat Yasin Asghar Abbas Khizar Samiullah Tehreem Raza Syed Sibt E. Hassan Rana Mehrooz Fazal Aqsa Noor Aeman Malik 《Open Journal of Geology》 2022年第6期521-564,共44页
Northern Koh Sulaiman foldbelt, Shirani, North and South Waziristan (South Punjab, Balochistan and Khyber Pakhtunkhwa) comprised mostly PermoTriassic to Recent sediments with subordinate igneous and metamorphic rocks.... Northern Koh Sulaiman foldbelt, Shirani, North and South Waziristan (South Punjab, Balochistan and Khyber Pakhtunkhwa) comprised mostly PermoTriassic to Recent sediments with subordinate igneous and metamorphic rocks. These sedimentary strata folded and faulted by geodynamic and tectonic forces occurred during Late Cretaceous to Recent revealed through anticlinal and synclinal foldings and active faultings. The Northern Koh Sulaiman foldbelt, Shirani, North and South Waziristan areas host many economic minerals like copper and chromite, construction stones, marble limestones, gypsum and cement resources, uranium and other radioactive mineral resources, low-quality iron, phosphate and muddy coal, high-quality gemstones, petroleum potential and excellent water resources and many other rocks and minerals. High-quality window and faden quartz crystals deposited in fractures and fissures as vugs and veins deposited by high-temperature hypothermal solution created by the tectonic compression process. The area has economic chromite and magnesite deposits. The Northern Koh Sulaiman foldbelt, Shirani, North and South Waziristan areas have large cement raw materials/resources (limestones, gypsum and shale/clays available mostly on same sites) which vitally need to install many cement industries in these areas because the ideal central location and now only one cement industry (Dera Ghazi Khan cement industry) is in operation. The Northern Koh Sulaiman foldbelt, Shirani, North and South Waziristan consists of excellent surface water resources which need the construction of smaller and medium-sized dams on different rud kohi/streams/rivers for the development of the area. Sakhi Sarwar area of Dera Ghazi Khan (South Punjab) yielded fossil of new Tomistominae (False Gharial) Gavialidae and further its surroundings recently yielded fossils of famous vertebrates like reptiles (dinosaurs, crocodiles, pterosaur and snake), birds and mammals, and tracks/trackways of Late Cretaceous archosaurs like Sauropaonia, Ornithopaonia and Pteropaonia. 展开更多
关键词 Stratigraphy Tectonic Structures Economic Minerals New False Gharial Northern Sulaiman Foldbelt Shirani North and South Waziristan Pakistan
下载PDF
Mobile Ad-Hoc Networks Applications and Its Challenges 被引量:1
8
作者 Naeem Raza Muhammad Umar Aftab +2 位作者 Muhammad Qasim Akbar Omair Ashraf Muhammad Irfan 《Communications and Network》 2016年第3期131-136,共6页
Mobile Ad-Hoc Network (MANET) is an infrastructure less wireless network of autonomous collection of mobile nodes (Smart phones, Laptops, iPads, PDAs etc.). Network is self-configured to reconstruct its topology and r... Mobile Ad-Hoc Network (MANET) is an infrastructure less wireless network of autonomous collection of mobile nodes (Smart phones, Laptops, iPads, PDAs etc.). Network is self-configured to reconstruct its topology and routing table information for the exchange of data packets on the joining and leaving of each node on ad-hoc basis. This paper is based on the MANET applications and challenges. The researchers can get the overall concept of MANET as well as its applications and challenges. 展开更多
关键词 MANET MANET Challenges and Applications
下载PDF
The Luminescence of a CuI Film Scintillator Controlled by a Distributed Bragg Reflector
9
作者 仝飞 朱智超 +3 位作者 刘波 易亚沙 顾牡 陈鸿 《Chinese Physics Letters》 SCIE CAS CSCD 2013年第2期214-216,共3页
We investigate the emission properties of CuI film scintillators and the effect of distributed Bragg reflectors.The free-exciton emission and the donor-acceptor pair emission from the CuI thin film with the peak wavel... We investigate the emission properties of CuI film scintillators and the effect of distributed Bragg reflectors.The free-exciton emission and the donor-acceptor pair emission from the CuI thin film with the peak wavelengths of 410 nm and 420 nm are observed.However,for the two emission bands,the distributed Bragg reflector reflection results in different enhancements,which is interpreted by the varying transmittance with wavelength.Angle-dependence of emission profile is decided by the transmittance and DBR reflection,which may be useful in scintillation detection applications. 展开更多
关键词 FILM DONOR BANDS
下载PDF
Clarification on Polarity of Bipolar Electric Field Solitary Structures in Space Plasmas with Satellite Observation
10
作者 M.N.S.Qureshi 史建魁 +1 位作者 Klaus Torkar 刘振兴 《Chinese Physics Letters》 SCIE CAS CSCD 2011年第2期164-167,共4页
The bipolar electric field solitary(EFS)structures observed frequently in space plasmas by satellites have two different polarities,first positive electric field peak then negative(i.e.,positive/negative)and first neg... The bipolar electric field solitary(EFS)structures observed frequently in space plasmas by satellites have two different polarities,first positive electric field peak then negative(i.e.,positive/negative)and first negative then positive peak(i.e.,negative/positive).We provide the physical explanation on the polarity of observed bipolar EFS structures with an electrostatic ion fluid model.The results show that if initial electric field𝐸E_(0)>0,the polarity of the bipolar EFS structure will be positive/negative;and if𝐸E_(0)<0,the polarity of the bipolar EFS structure will be negative/positive.However,for a fixed polarity of the EFS,either positive/negative or negative/positive,if the satellite is located at the positive side of the EFS,the observed polarity should be positive/negative,if the satellite is located at the negative side of the EFS,the observed polarity should be negative/positive.Therefore,we provide a method to clarify the natural polarity of the EFS with observed polarity by satellites.Our results are significant to understand the physical process in space plasma with the satellite observation. 展开更多
关键词 OBSERVATION polarity BIPOLAR
下载PDF
A proposed model for understanding human-bacterial interactions:Space-time approach on community Escherichia coli occurrence and resistance phenomenon
11
作者 Carlos R.V.Kiffer Antonio M.V.Monteiro +1 位作者 Eduardo C.G.Camargo Antonio C.C.Pignatari 《Advances in Bioscience and Biotechnology》 2013年第4期505-508,共4页
Due to ecological effect, it is expected that population exposures to antimicrobial drugs may lead to microorganisms’ modifications, occasionally leading to resistance emergence. The present review was based on previ... Due to ecological effect, it is expected that population exposures to antimicrobial drugs may lead to microorganisms’ modifications, occasionally leading to resistance emergence. The present review was based on previous empirical data and on related literature search for quantitative empirical models exploring the human-bacterial interactions. Our previous studies have shown the emergence of ciprofloxacin resistant (CIP-R) Escherichia coli significantly related to previous specific levels of ciprofloxacin consumption and to urban clusters of CIP-R E. coli. The evidence of significant spatial clustering of antimicrobial resistance (ciprofloxacin resistance E. coli) reinforces the ecological effect hypothesis as a major drive in resistance emergence. In other words, human populations submitted to a certain ciprofloxacin or quinolone usage level may affect neighbours within certain geographical areas, not necessarily due to individual antimicrobial intake, but as a driving pressure over a modified circulating E. coli population. Apparently quantitative spatial-temporal analytical frameworks may be better for understanding human-bacterial interactions based on any of their epiphenomena (antimicrobial consumption, antimicrobial resistance, geno/phenotypic characteristics). 展开更多
关键词 Escherichia coli Antimicrobial Agents MICROBIOME
下载PDF
一个由干湿交替极端气候事件主导的内陆湖盆:来自鄂尔多斯盆地上三叠统延长组露头剖面的沉积学证据 被引量:3
12
作者 李相博 刘化清 +7 位作者 杨伟伟 张艳 Carlos Zavala 吉利民 杨占龙 郝彬 黄军平 王菁 《地球科学》 EI CAS CSCD 北大核心 2023年第1期293-316,共24页
鄂尔多斯盆地是我国陆上最主要的油气盆地之一,三叠系延长组是该盆地的主要含油层位.通过对延长组典型露头的考察与研究,结合古生物及岩性岩相资料,取得了3点新认识:(1)恢复了延长组沉积时期的古气候环境,认为其具有三分性,其中早期拉... 鄂尔多斯盆地是我国陆上最主要的油气盆地之一,三叠系延长组是该盆地的主要含油层位.通过对延长组典型露头的考察与研究,结合古生物及岩性岩相资料,取得了3点新认识:(1)恢复了延长组沉积时期的古气候环境,认为其具有三分性,其中早期拉丁期为干旱环境;中期受卡尼期梅雨事件(CPE)影响气候发生突变,转变为温暖潮湿气候环境;晚期诺利-瑞替期再次转变为半干旱-半湿润气候环境.(2)CPE事件改变了延长组沉积物搬运与沉积方式,其中CPE事件之前与事件之后的干旱环境时期,主要发育暴雨洪水引发的季节性河流、决口扇、决口河道沉积;CPE事件当中及卡尼中期,陆源碎屑物质主要通过异重流、浊流及砂质碎屑流等多种途径搬运至水下环境,形成富砂质重力流事件沉积,同时受CPE事件控制,在深水环境还发育了黑色富有机质页岩事件沉积.(3)建立了延长组干旱与潮湿两种环境沉积模式,干旱环境湖泊水域面积较小,主要沉积单元为洪泛平原、季节性河道及决口扇,主要沉积方式为填平补齐、加积式沉积,不发育前积沉积现象;潮湿环境湖泊水域面积较大,发育完整的陆相河流-三角洲-湖泊-重力流沉积体系,由于具有稳定的长流水,河道相对固定,加之受湖平面变化控制,其沉积方式以前积作用为主.该认识不仅对于深入探讨鄂尔多斯延长组大型坳陷湖盆形成演化机理、沉积层序充填演化及指导油气勘探实践有积极意义,而且对揭示晚三叠世全球极端气候事件在内陆湖盆的沉积学记录有积极意义,可以填补CPE事件在古特提斯东缘泛大陆内部沉积响应研究的空白. 展开更多
关键词 干湿气候交替 洪水事件 梅雨事件 沉积模式 延长组 晚三叠世 鄂尔多斯盆地 石油地质学
原文传递
重视重组人干扰素α1b的创新研究和儿科临床应用 被引量:43
13
作者 侯云德 张国成 《中华实用儿科临床杂志》 CSCD 北大核心 2018年第18期1361-1365,共5页
重组人干扰素α1b(IFNα1b)作为中国第一个基因工程Ⅰ类新药,具有独特的生物学意义及临床价值。特别是在儿科领域,IFNα1b用于小儿病毒性肺炎、病毒性肝炎、毛细支气管炎、疱疹性咽峡炎、手足口病和某些肿瘤的治疗,均显示了确切的... 重组人干扰素α1b(IFNα1b)作为中国第一个基因工程Ⅰ类新药,具有独特的生物学意义及临床价值。特别是在儿科领域,IFNα1b用于小儿病毒性肺炎、病毒性肝炎、毛细支气管炎、疱疹性咽峡炎、手足口病和某些肿瘤的治疗,均显示了确切的疗效和良好的安全性,近期在病毒相关的喘息性疾病、流感等重大传染病防治领域展现了更大的应用前景,为促进我国儿童健康发挥了重要作用。现就IFNα1b的基因和分子特点、新型递送方式及儿童应用的前沿研究成果进行阐述和讨论。 展开更多
关键词 干扰素Α1B 儿童 病毒 雾化吸入 喘息 流感
原文传递
一种红外与可见光融合的“双双目”立体视觉系统的标定方法研究 被引量:7
14
作者 赵美蓉 李瀚辰 佟颖 《光学技术》 CAS CSCD 北大核心 2017年第5期385-393,共9页
针对红外相机与可见光相机联合标定的问题,利用不同物体红外辐出度的差异,设计了可同时应用于红外相机与可见光相机标定的平面靶标。利用"最大稳定极值区域"(MSER)算法,检测靶标的镂空深色区域。为克服图像可能存在较大畸变... 针对红外相机与可见光相机联合标定的问题,利用不同物体红外辐出度的差异,设计了可同时应用于红外相机与可见光相机标定的平面靶标。利用"最大稳定极值区域"(MSER)算法,检测靶标的镂空深色区域。为克服图像可能存在较大畸变的问题,通过相邻最大稳定极值区域质心的位置关系预估角点所在位置,在预估位置内进行角点检测,提取用于标定的亚像素角点位置。结果表明:新型靶标及相应的角点提取方法能够同时满足于红外相机与可见光相机内外参数标定的需要。通过红外与可见光"双双目"立体视觉系统的融合重构效果可看出,提供的标定数据能够满足系统需求。 展开更多
关键词 几何光学 相机标定 红外相机标定 最大稳定极值区域 “双双目”视觉系统
原文传递
姜黄素增强人胆管癌细胞株QBC939对吉西他滨敏感性的研究 被引量:4
15
作者 徐杰伟 邱建 +2 位作者 董顺利 钟婧 叶国超 《中华实验外科杂志》 CAS CSCD 北大核心 2018年第10期1862-1864,共3页
目的探讨姜黄素对人胆管癌细胞株QBC939吉西他滨的增敏作用及其机制研究。方法将人胆管癌细胞QBC939培养后分为对照组、5μg/m1单药姜黄素组、0.625μg/m1单药吉西他滨组及5μg/m1姜黄素联合0.625μg/m1吉西他滨组,采用噻唑蓝(... 目的探讨姜黄素对人胆管癌细胞株QBC939吉西他滨的增敏作用及其机制研究。方法将人胆管癌细胞QBC939培养后分为对照组、5μg/m1单药姜黄素组、0.625μg/m1单药吉西他滨组及5μg/m1姜黄素联合0.625μg/m1吉西他滨组,采用噻唑蓝(MTT)法检测细胞增殖、流式细胞仪检测细胞周期及凋亡变化,同时用Westernblot法检测相关蛋白核因子±κB(NF±κB)、细胞周期蛋白(Cyclin)B1、凋亡抑制蛋白(1AP)-1的表达改变。结果姜黄素联合吉西他滨处理人胆管癌细胞QBC939后12、24、48、72h的抑制率分别为(10.00±0.02)%、(23.10±0.03)%、(33.234±0.01)%、(48.304±0.05)%,显著高于对照组及单药组(P=0.001、0.000、0.000、0.000)。两药联合作用后能使(28.75±3.23)%的人胆管癌细胞QBC939被阻滞在G2/M期,显著高于单药姜黄素组及单药吉西他滨组[(14.494±2.20)%、(11.824±2.10)%;P=0.000],且细胞凋亡率为(13.644±3.40)%,显著高于对照组、单药姜黄素组及单药吉西他滨组[(4.534±0.56)%、(6.47±0.98)%、(9.874±1.12)%,P=0.000];姜黄素联合吉西他滨作用于人胆管癌细胞株QBC939后NF±κB及下游分子CyclinB1和IAP±1蛋白的相对表达量分别为0.3004±0.001、0.4074±0.036、0.4754±0.032,显著低于对照组、单药姜黄素组及单药吉西他滨组(P=0.000、0.001、0.003)。结论姜黄素可增强人胆管癌细胞株QBC939对吉西他滨的敏感性,其机制可能与NF±κB信号通路的抑制相关。 展开更多
关键词 胆管细胞癌 姜黄素 吉西他滨 人胆管癌细胞株QBC939 核因子-ΚB
原文传递
伴髓外病变的多发性骨髓瘤的诊治进展 被引量:4
16
作者 郭冬梅 白观臣 +2 位作者 李斑斑 林海 滕清良 《国际输血及血液学杂志》 CAS 2018年第4期338-342,共5页
伴髓外病变(EMD)的多发性骨髓瘤(MM)为MM患者存在骨髓外浆细胞的浸润.DC(Durie-Salmon)-PLUS分期系统新纳入EMD因素对MM患者进行预后评估.临床上推荐全身MRI与正电子发射断层显像(PET)/CT为伴EMD的MM患者诊断与疗效评估的工具.... 伴髓外病变(EMD)的多发性骨髓瘤(MM)为MM患者存在骨髓外浆细胞的浸润.DC(Durie-Salmon)-PLUS分期系统新纳入EMD因素对MM患者进行预后评估.临床上推荐全身MRI与正电子发射断层显像(PET)/CT为伴EMD的MM患者诊断与疗效评估的工具.伴EMD提示初诊与复发MM患者的预后不良.伴EMD的MM患者预后较差,复发的伴EMD的MM患者的中位总体生存(OS)期<6个月.伴EMD的MM为高风险骨髓瘤,临床应该予以积极治疗.为了增强对伴EMD的MM诊治的认识,笔者拟就伴EMD的MM患者的临床表现特点及诊治方法进行综述. 展开更多
关键词 多发性骨髓瘤 诊断 治疗 预后 髓外病变
原文传递
单臂和Taylor外固定治疗老年GustiloⅡ型胫腓骨骨折患者临床疗效及有限元分析 被引量:3
17
作者 汪松 孙倩 +3 位作者 冯硕 查国春 史进 耿猛 《中华老年医学杂志》 CAS CSCD 北大核心 2018年第9期1004-1008,共5页
目的比较单臂外固定支架(UF)和Taylor外固定支架(TF)治疗老年GustiloⅡ型胫腓骨骨折患者临床疗效和生物力学性能。方法回顾性分析2012年1月至2015年8月采用uF和TF固定治疗的86例开放性胫腓骨骨折患者资料。根据骨外固定不同方式分为... 目的比较单臂外固定支架(UF)和Taylor外固定支架(TF)治疗老年GustiloⅡ型胫腓骨骨折患者临床疗效和生物力学性能。方法回顾性分析2012年1月至2015年8月采用uF和TF固定治疗的86例开放性胫腓骨骨折患者资料。根据骨外固定不同方式分为2组:UF组49例,TF组37例,比较两组患者的临床效果。在充分验证有限元模型有效性的前提下,对UF和TF分别进行轴向、扭转和弯曲试验,其中弯曲实验为环绕有限元模型每隔10。进行评估。结果uF组患者手术时间为(43.2±11.7)min,术中出血量为(32.1±13.8)ml,低于TF组患者[(63.6±9.8)min,(57.6±23.1)m1]。所有患者术后获8-31个月(平均13.8个月)随访。UF组患者愈合时间为(4.6±1.7)个月,术后并发症发生率为4.5%(9/201),均优于TF组患者[(5.7±2.1)个月,12.0%(14/117)](P〈0.05)。uF轴向刚度341.47N/m,扭转刚度80.00 Nm/deg,均高于TF(226.83N/m,72.00 Nm/deg);uF组弯曲刚度为210.00-430.00N/m,变化幅度高于TF组(242.00-287.00N/m)。结论uF外固定支架治疗开放性胫腓骨骨折操作简单,更符合胫腓骨的生物力学特性,具有较好的抗压、抗弯和防旋能力。相对于Taylor外固定支架,单臂支架更有利于骨折愈合,具有明显优势。 展开更多
关键词 骨折固定术 胫骨骨折 腓骨骨折 有限元分析
原文传递
PE回购退出的国资监管问题——以一起参与国企混改的PE回购退出案件为切入点 被引量:1
18
作者 王甲国 《行政法学研究》 CSSCI 北大核心 2019年第2期78-89,共12页
国有企业的混合所有制改革,需要具备资本及管理优势的私募股权基金(以下简称"PE")的参与。在越来越多的PE参与到国企混改之中,且PE多与国资股东存在对赌回购约定的情况下,通过在国资监管层面明确国资参与对赌的效力边界并增... 国有企业的混合所有制改革,需要具备资本及管理优势的私募股权基金(以下简称"PE")的参与。在越来越多的PE参与到国企混改之中,且PE多与国资股东存在对赌回购约定的情况下,通过在国资监管层面明确国资参与对赌的效力边界并增强行政相对人的合理预期保护,推进国资股东回购PE所持股权定价的市场化进程,完善股权收益权可转让的相关规定,以及通过行政主管机关合法决策方式确保地方产权交易所可挂牌交易权利类型的可覆盖性,可以为鼓励PE积极参与国企混改构建回购退出路径,从而实现国有资产保值增值的目标。 展开更多
关键词 国企混改 私募股权投资基金 回购退出 国资监管/定价 股权收益权转让
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部