基金supported by the National Natural Science Foundation of China(U20A20371)the National Key Technology Research and Development Program of the Ministry of Science and Technology of China(D171100006517004)+3 种基金Beijing Municipal Administration of Hospitals’Youth Program(QML20191103)Clinical Medicine Plus X-Young Scholars Project,Peking Universitythe Fundamental Research Funds for the Central Universitiesthe Science Foundation of Peking University Cancer Hospital。