Approximately 20%-25%of adults encounter metabolic syndrome(MetS)worldwide,and MetS is a riskfactorfor cognitive decline(CD)development.Patients with MetS have an 11.48-fold increased incidence of CD compared with tho...Approximately 20%-25%of adults encounter metabolic syndrome(MetS)worldwide,and MetS is a riskfactorfor cognitive decline(CD)development.Patients with MetS have an 11.48-fold increased incidence of CD compared with those without Mets.^(1) Ataxia-telangiectasia mutated(ATM)gene encodes ATM kinase,which belongs to the phosphatidylinositol 3-hydroxy kinase family.展开更多
基金supported by grants from the Military Medical Science and Technology Youth Incubation Program(No.20QNPY110,19QNP060)the National Natural Science Foundation of China(No.81900357,81941021,81903392,81901252,82001476,81802804,81801251)+8 种基金the Excellent Youth Incubation Program of Chinese People's Liberation Army General Hospital(No.2020-YQPY-007)the Natural Science Foundation of Hainan Province,China(No.821QN389,821MS112,822MS198,820MS126,820QN383)the National Key R&D Program of China(No.2018YFC2000400)the National S&T Resource Sharing Service Platform Project of China(No.YCZYPT[2018]07)the Specific Research Fund of Innovation Platform for Academicians of Hainan Province,China(No.YSPTZX202216)the Medical Big Data R&D Project of Chinese People's Liberation Army General Hospital(No.MBD2018030)the China Postdoctoral Science Foundation Funded Project(No.2019M650359,2020M682816,2021T140298)the Heatstroke Treatment and Research Center of Chinese People's Liberation Army,the Simulation Training for Treatment of Heat Strokethe Major Science and Technology Programme of Hainan Province,China(No.ZDKJ2019012).
文摘Approximately 20%-25%of adults encounter metabolic syndrome(MetS)worldwide,and MetS is a riskfactorfor cognitive decline(CD)development.Patients with MetS have an 11.48-fold increased incidence of CD compared with those without Mets.^(1) Ataxia-telangiectasia mutated(ATM)gene encodes ATM kinase,which belongs to the phosphatidylinositol 3-hydroxy kinase family.