Early linkage to antiretroviral therapy (ART) after HIV diagnosis extends life. Low socioeconomic populations with HIV face regional concerns that inhibit early treatment. Barriers include religious-based stigma, lack...Early linkage to antiretroviral therapy (ART) after HIV diagnosis extends life. Low socioeconomic populations with HIV face regional concerns that inhibit early treatment. Barriers include religious-based stigma, lack of local treatment facilities, fear of discovery and purposeful secrecy fostering increased HIV transmission and decreased ART adherence. This ethnographic qualitative study employed semi-structured interviews with 10 health care providers (HCP) and 10 people living with HIV (PLWH) to discover methods to streamline care and increase medication adherence. Clients perceive enhanced care when they are active participants in treatment. HCPs reported positive health outcomes when there was active multidisciplinary communication. Obstacles included a lack of consistent medication assistance programs, homelessness, and limited access to specialized services. There is a need for further investigation on how to provide individualized, holistic treatment to a population of patients with extremely limited federal funding in a geographic region where religious stigma surrounding HIV is widespread.展开更多
Background:The development of computer vision technology has enabled the use of markerless movement tracking for biomechanical analysis.Recent research has reported the feasibility of markerless systems in motion anal...Background:The development of computer vision technology has enabled the use of markerless movement tracking for biomechanical analysis.Recent research has reported the feasibility of markerless systems in motion analysis but has yet to fully explore their utility for capturing faster movements,such as running.Applied studies using markerless systems in clinical and sports settings are still lacking.Thus,the present study compared running biomechanics estimated by marker-based and markerless systems.Given running speed not only affects sports performance but is also associated with clinical injury prevention,diagnosis,and rehabilitation,we aimed to investigate the effects of speed on the comparison of estimated lower extremity joint moments and powers between markerless and marker-based technologies during treadmill running as a concurrent validating study.Methods:Kinematic data from marker-based/markerless technologies were collected,along with ground reaction force data,from 16 young adults running on an instrumented treadmill at 3 speeds:2.24 m/s,2.91 m/s,and 3.58 m/s(5.0 miles/h,6.5 miles/h,and 8.0 miles/h).Sagittal plane moments and powers of the hip,knee,and ankle were calculated by inverse dynamic methods.Time series analysis and statistical parametric mapping were used to determine system differences.Results:Compared to the marker-based system,the markerless system estimated increased lower extremity joint kinetics with faster speed during the swing phase in most cases.Conclusion:Despite the promising application of markerless technology in clinical settings,systematic markerless overestimation requires focused attention.Based on segment pose estimations,the centers of mass estimated by markerless technologies were farther away from the relevant distal joint centers,which led to greater joint moments and powers estimates by markerless vs.marker-based systems.The differences were amplified by running speed.展开更多
This investigation is focused on conducting a thorough analysis of Municipal Solid Waste Management (MSWM). MSWM encompasses a range of interdisciplinary measures that govern the various stages involved in managing un...This investigation is focused on conducting a thorough analysis of Municipal Solid Waste Management (MSWM). MSWM encompasses a range of interdisciplinary measures that govern the various stages involved in managing unwanted or non-utilizable solid materials, commonly known as rubbish, trash, junk, refuse, and garbage. These stages include generation, storage, collection, recycling, transportation, handling, disposal, and monitoring. The waste materials mentioned in this context exhibit a wide range of items, such as organic waste from food and vegetables, paper, plastic, polyethylene, iron, tin cans, deceased animals, byproducts from demolition activities, manure, and various other discarded materials. This study aims to provide insights into the possibilities of enhancing solid waste management in the Farmgate area of Dhaka North City Corporation (DNCC). To accomplish this objective, the research examines the conventional waste management methods employed in this area. It conducts extensive field surveys, collecting valuable data through interviews with local residents and key individuals involved in waste management, such as waste collectors, dealers, intermediate dealers, recyclers, and shopkeepers. The results indicate that significant amounts of distinct waste categories are produced daily. These include food and vegetable waste, which amount to 52.1 tons/day;polythene and plastic, which total 4.5 tons/day;metal and tin-can waste, which amounts to 1.4 tons/day;and paper waste, which totals 5.9 tons/day. This study highlights the significance of promoting environmental consciousness to effectively shape the attitudes of urban residents toward waste disposal and management. It emphasizes the need for collaboration between authorities and researchers to improve the current waste management system.展开更多
In this paper,we study the ground state standing wave solutions for the focusing bi-harmonic nonlinear Schrodinger equation with aμ-Laplacian term(BNLS).Such BNLS models the propagation of intense laser beams in a bu...In this paper,we study the ground state standing wave solutions for the focusing bi-harmonic nonlinear Schrodinger equation with aμ-Laplacian term(BNLS).Such BNLS models the propagation of intense laser beams in a bulk medium with a second-order dispersion term.Denoting by Qpthe ground state for the BNLS withμ=0,we prove that in the mass-subcritical regime p∈(1,1+8/d),there exist orbit ally stable ground state solutions for the BNLS when p∈(-λ0,∞)for someλ0=λ0(p,d,‖Qp‖L2)>0.Moreover,in the mass-critical case p=1+8/d,we prove the orbital stability on a certain mass level below‖Q*‖L2,provided thatμ∈(-λ1,0),where■and Q*=Q1+8/d.The proofs are mainly based on the profile decomposition and a sharp Gagliardo-Nirenberg type inequality.Our treatment allows us to fill the gap concerning the existence of the ground states for the BNLS when p is negative and p∈(1,1+8/d].展开更多
This paper presents findings on dynamic cell modeling for state-of-charge (SOC) estimation in an autonomous electric vehicle (AEV). The studied cells are Lithium-Ion Polymer-based with a nominal capacity of around 8 A...This paper presents findings on dynamic cell modeling for state-of-charge (SOC) estimation in an autonomous electric vehicle (AEV). The studied cells are Lithium-Ion Polymer-based with a nominal capacity of around 8 Ah, optimized for power-needy applications. The AEV operates in a harsh environment with rate requirements up to ±25C and highly dynamic rate profiles, unlike portable-electronic applications with constant power output and fractional C rates. SOC estimation methods effective in portable electronics may not suffice for the AEV. Accurate SOC estimation necessitates a precise cell model. The proposed SOC estimation method utilizes a detailed Kalman-filtering approach. The cell model must include SOC as a state in the model state vector. Multiple cell models are presented, starting with a simple one employing “Coulomb counting” as the state equation and Shepherd’s rule as the output equation, lacking prediction of cell relaxation dynamics. An improved model incorporates filter states to account for relaxation and other dynamics in closed-circuit cell voltage, yielding better performance. The best overall results are achieved with a method combining nonlinear autoregressive filtering and dynamic radial basis function networks. The paper includes lab test results comparing physical cells with model predictions. The most accurate models obtained have an RMS estimation error lower than the quantization noise floor expected in the battery-management-system design. Importantly, these models enable precise SOC estimation, allowing the vehicle controller to utilize the battery pack’s full operating range without overcharging or undercharging concerns.展开更多
Bormate （BrO3^-） is a carcinogenic chemical produced in ozonation or chlorination of bromide-containing water. Although its formation in seawater with or without sunlight has been previously investigated, the format...Bormate （BrO3^-） is a carcinogenic chemical produced in ozonation or chlorination of bromide-containing water. Although its formation in seawater with or without sunlight has been previously investigated, the formation of bromate in dilute solutions, particularly raw water for water treatment plant, is unknown. In this article, the results of bench scale tests to measure the formation rates of bromate formation in dilute solutions, including de-ionized water and raw water from Yangtze River, were presented in dark chlorination and ultraviolet （UV）/chlorination processes. And the effects of initial pH, initial concentration of NaOCl, and UV light intensity on bromate formation in UV/chlorination of the diluted solutions were investigated. Detectable bromate was formed in dark chlorination of the two water samples with a relatively slow production rate. Under routine disinfecting conditions, the amount of formed bromate is not likely to exceed the national standards （10 μg/L）. UV irradiation enhanced the decay of free chlorine, and, simultaneously, 6.6%-32% of Br^- was oxidized to BrO3^-. And the formation of bromate exhibited three stages： rapid stage, slow stage and plateau. Under the experimental conditions （pH = 4.41-11.07, CCl2= 1.23-4.50 mg/L）, low pH and high chlorine concentration favored the generation of bromate. High light intensity promoted the production rate of bromate, but decreased its total generation amount due to acceleration of chlorine decomposition.展开更多
Peripheral neuropathy(PN) is a multifarious disorder that is caused by damage to the peripheral nerves. Although the symptoms of PN vary with the etiology, most cases are characterized by impaired tactile and proprioc...Peripheral neuropathy(PN) is a multifarious disorder that is caused by damage to the peripheral nerves. Although the symptoms of PN vary with the etiology, most cases are characterized by impaired tactile and proprioceptive sensation that progresses in a distal to proximal manner. Balance also tends to deteriorate as the disorder becomes more severe, and those afflicted are substantially more likely to fall while walking compared with those who are healthy. Most patients with PN walk more cautiously and with greater stride variability than age-matched controls, but the majority of their falls occur when they must react to a perturbation such as a slippery or uneven surface. The purpose of this study was to first describe the role of somatosensory feedback in the control of posture and then discuss how that relationship is typically affected by the most common types of PN. A comprehensive review of the scientific literature was conducted using MEDLINE, and the relevant information was synthesized. The evidence indicates that the proprioceptive feedback that is conveyed primarily through larger type I afferents is important for postural control. However, the evidence indicates that the tactile feedback communicated through smaller type II afferents is particularly critical to the maintenance of balance. Many forms of PN often lead to chronic tactile desensitization in the soles of the feet and, although the central nervous system seems to adapt to this smaller type II afferent dysfunction by relying on more larger type I afferent reflex loops, the result is still decreased stability. We propose a model that is intended both to help explain the relationship between stability and the smaller type II afferent and the larger type I afferent feedback that may be impaired by PN and to assist in the development of pertinent rehabilitative interventions.展开更多
文摘Early linkage to antiretroviral therapy (ART) after HIV diagnosis extends life. Low socioeconomic populations with HIV face regional concerns that inhibit early treatment. Barriers include religious-based stigma, lack of local treatment facilities, fear of discovery and purposeful secrecy fostering increased HIV transmission and decreased ART adherence. This ethnographic qualitative study employed semi-structured interviews with 10 health care providers (HCP) and 10 people living with HIV (PLWH) to discover methods to streamline care and increase medication adherence. Clients perceive enhanced care when they are active participants in treatment. HCPs reported positive health outcomes when there was active multidisciplinary communication. Obstacles included a lack of consistent medication assistance programs, homelessness, and limited access to specialized services. There is a need for further investigation on how to provide individualized, holistic treatment to a population of patients with extremely limited federal funding in a geographic region where religious stigma surrounding HIV is widespread.
文摘Background:The development of computer vision technology has enabled the use of markerless movement tracking for biomechanical analysis.Recent research has reported the feasibility of markerless systems in motion analysis but has yet to fully explore their utility for capturing faster movements,such as running.Applied studies using markerless systems in clinical and sports settings are still lacking.Thus,the present study compared running biomechanics estimated by marker-based and markerless systems.Given running speed not only affects sports performance but is also associated with clinical injury prevention,diagnosis,and rehabilitation,we aimed to investigate the effects of speed on the comparison of estimated lower extremity joint moments and powers between markerless and marker-based technologies during treadmill running as a concurrent validating study.Methods:Kinematic data from marker-based/markerless technologies were collected,along with ground reaction force data,from 16 young adults running on an instrumented treadmill at 3 speeds:2.24 m/s,2.91 m/s,and 3.58 m/s(5.0 miles/h,6.5 miles/h,and 8.0 miles/h).Sagittal plane moments and powers of the hip,knee,and ankle were calculated by inverse dynamic methods.Time series analysis and statistical parametric mapping were used to determine system differences.Results:Compared to the marker-based system,the markerless system estimated increased lower extremity joint kinetics with faster speed during the swing phase in most cases.Conclusion:Despite the promising application of markerless technology in clinical settings,systematic markerless overestimation requires focused attention.Based on segment pose estimations,the centers of mass estimated by markerless technologies were farther away from the relevant distal joint centers,which led to greater joint moments and powers estimates by markerless vs.marker-based systems.The differences were amplified by running speed.
文摘This investigation is focused on conducting a thorough analysis of Municipal Solid Waste Management (MSWM). MSWM encompasses a range of interdisciplinary measures that govern the various stages involved in managing unwanted or non-utilizable solid materials, commonly known as rubbish, trash, junk, refuse, and garbage. These stages include generation, storage, collection, recycling, transportation, handling, disposal, and monitoring. The waste materials mentioned in this context exhibit a wide range of items, such as organic waste from food and vegetables, paper, plastic, polyethylene, iron, tin cans, deceased animals, byproducts from demolition activities, manure, and various other discarded materials. This study aims to provide insights into the possibilities of enhancing solid waste management in the Farmgate area of Dhaka North City Corporation (DNCC). To accomplish this objective, the research examines the conventional waste management methods employed in this area. It conducts extensive field surveys, collecting valuable data through interviews with local residents and key individuals involved in waste management, such as waste collectors, dealers, intermediate dealers, recyclers, and shopkeepers. The results indicate that significant amounts of distinct waste categories are produced daily. These include food and vegetable waste, which amount to 52.1 tons/day;polythene and plastic, which total 4.5 tons/day;metal and tin-can waste, which amounts to 1.4 tons/day;and paper waste, which totals 5.9 tons/day. This study highlights the significance of promoting environmental consciousness to effectively shape the attitudes of urban residents toward waste disposal and management. It emphasizes the need for collaboration between authorities and researchers to improve the current waste management system.
基金partially supported by the National Natural Science Foundation of China(11501137)partially supported by the National Natural Science Foundation of China(11501395,12071323)the Guangdong Basic and Applied Basic Research Foundation(2016A030310258,2020A1515011019)。
文摘In this paper,we study the ground state standing wave solutions for the focusing bi-harmonic nonlinear Schrodinger equation with aμ-Laplacian term(BNLS).Such BNLS models the propagation of intense laser beams in a bulk medium with a second-order dispersion term.Denoting by Qpthe ground state for the BNLS withμ=0,we prove that in the mass-subcritical regime p∈(1,1+8/d),there exist orbit ally stable ground state solutions for the BNLS when p∈(-λ0,∞)for someλ0=λ0(p,d,‖Qp‖L2)>0.Moreover,in the mass-critical case p=1+8/d,we prove the orbital stability on a certain mass level below‖Q*‖L2,provided thatμ∈(-λ1,0),where■and Q*=Q1+8/d.The proofs are mainly based on the profile decomposition and a sharp Gagliardo-Nirenberg type inequality.Our treatment allows us to fill the gap concerning the existence of the ground states for the BNLS when p is negative and p∈(1,1+8/d].
文摘This paper presents findings on dynamic cell modeling for state-of-charge (SOC) estimation in an autonomous electric vehicle (AEV). The studied cells are Lithium-Ion Polymer-based with a nominal capacity of around 8 Ah, optimized for power-needy applications. The AEV operates in a harsh environment with rate requirements up to ±25C and highly dynamic rate profiles, unlike portable-electronic applications with constant power output and fractional C rates. SOC estimation methods effective in portable electronics may not suffice for the AEV. Accurate SOC estimation necessitates a precise cell model. The proposed SOC estimation method utilizes a detailed Kalman-filtering approach. The cell model must include SOC as a state in the model state vector. Multiple cell models are presented, starting with a simple one employing “Coulomb counting” as the state equation and Shepherd’s rule as the output equation, lacking prediction of cell relaxation dynamics. An improved model incorporates filter states to account for relaxation and other dynamics in closed-circuit cell voltage, yielding better performance. The best overall results are achieved with a method combining nonlinear autoregressive filtering and dynamic radial basis function networks. The paper includes lab test results comparing physical cells with model predictions. The most accurate models obtained have an RMS estimation error lower than the quantization noise floor expected in the battery-management-system design. Importantly, these models enable precise SOC estimation, allowing the vehicle controller to utilize the battery pack’s full operating range without overcharging or undercharging concerns.
文摘Bormate （BrO3^-） is a carcinogenic chemical produced in ozonation or chlorination of bromide-containing water. Although its formation in seawater with or without sunlight has been previously investigated, the formation of bromate in dilute solutions, particularly raw water for water treatment plant, is unknown. In this article, the results of bench scale tests to measure the formation rates of bromate formation in dilute solutions, including de-ionized water and raw water from Yangtze River, were presented in dark chlorination and ultraviolet （UV）/chlorination processes. And the effects of initial pH, initial concentration of NaOCl, and UV light intensity on bromate formation in UV/chlorination of the diluted solutions were investigated. Detectable bromate was formed in dark chlorination of the two water samples with a relatively slow production rate. Under routine disinfecting conditions, the amount of formed bromate is not likely to exceed the national standards （10 μg/L）. UV irradiation enhanced the decay of free chlorine, and, simultaneously, 6.6%-32% of Br^- was oxidized to BrO3^-. And the formation of bromate exhibited three stages： rapid stage, slow stage and plateau. Under the experimental conditions （pH = 4.41-11.07, CCl2= 1.23-4.50 mg/L）, low pH and high chlorine concentration favored the generation of bromate. High light intensity promoted the production rate of bromate, but decreased its total generation amount due to acceleration of chlorine decomposition.
文摘Peripheral neuropathy(PN) is a multifarious disorder that is caused by damage to the peripheral nerves. Although the symptoms of PN vary with the etiology, most cases are characterized by impaired tactile and proprioceptive sensation that progresses in a distal to proximal manner. Balance also tends to deteriorate as the disorder becomes more severe, and those afflicted are substantially more likely to fall while walking compared with those who are healthy. Most patients with PN walk more cautiously and with greater stride variability than age-matched controls, but the majority of their falls occur when they must react to a perturbation such as a slippery or uneven surface. The purpose of this study was to first describe the role of somatosensory feedback in the control of posture and then discuss how that relationship is typically affected by the most common types of PN. A comprehensive review of the scientific literature was conducted using MEDLINE, and the relevant information was synthesized. The evidence indicates that the proprioceptive feedback that is conveyed primarily through larger type I afferents is important for postural control. However, the evidence indicates that the tactile feedback communicated through smaller type II afferents is particularly critical to the maintenance of balance. Many forms of PN often lead to chronic tactile desensitization in the soles of the feet and, although the central nervous system seems to adapt to this smaller type II afferent dysfunction by relying on more larger type I afferent reflex loops, the result is still decreased stability. We propose a model that is intended both to help explain the relationship between stability and the smaller type II afferent and the larger type I afferent feedback that may be impaired by PN and to assist in the development of pertinent rehabilitative interventions.
