China is currently vigorously implementing the“energy conservation and emission reduction”and“dual carbon”strategies.As the most resource-advantaged light metal material in China,Magnesium(Mg)alloy is progressivel...China is currently vigorously implementing the“energy conservation and emission reduction”and“dual carbon”strategies.As the most resource-advantaged light metal material in China,Magnesium(Mg)alloy is progressively expanding its application in automobile,rail transportation,aerospace,medical,and electronic products.Chongqing University,Shanghai Jiaotong University,and Australian National University have conducted extensive research on the preparation,properties,and processes of Mg alloys.In the past 20 years,the proportion of Mg alloy in the automotive industry has gradually expanded,whereas currently the design and development of Mg alloy parts for automobiles has rarely been reported.Thus,the application models and typical parts cases of Mg alloy are summarized mainly from the four systems of the whole vehicle(body system,chassis system,powertrain system,interior,and exterior system).Subsequently,two actual original equipment manufacturers(OEM)cases are used to introduce the development logic of reliable die-cast Mg alloy,including forward design,formability analysis,process design analysis,structural redesign,manufacturing,and testing,aiming to share the methods,processes,and focus of attention of automotive OEMs for developing Mg alloy parts to enhance the confidence and motivation of applying Mg alloy in automotive field.Eventually,the multiple challenges faced by Mg alloy materials are sorted out and how to face these challenges are discussed.National policies and regulations,environmental protection and energy saving,and consumer demand will continue to promote the application of Mg.展开更多
The fundamental research on thermo-mechanical conditions provides an experimental basis for high-performance Mg-Al-Ca-Mn alloys.However, there is a lack of systematical investigation for this series alloys on the hot-...The fundamental research on thermo-mechanical conditions provides an experimental basis for high-performance Mg-Al-Ca-Mn alloys.However, there is a lack of systematical investigation for this series alloys on the hot-deformation kinetics and extrusion parameter optimization. Here, the flow behavior, constitutive model, dynamic recrystallization(DRX) kinetic model and processing map of a dilute rare-earth free Mg-1.3Al-0.4Ca-0.4Mn(AXM100, wt.%) alloy were studied under different hot-compressive conditions. In addition, the extrusion parameter optimization of this alloy was performed based on the hot-processing map. The results showed that the conventional Arrhenius-type strain-related constitutive model only worked well for the flow curves at high temperatures and low strain rates. In comparison, using the machine learning assisted model(support vector regression, SVR) could effectively improve the accuracy between the predicted and experimental values. The DRX kinetic model was established, and a typical necklace-shaped structure preferentially occurred at the original grain boundaries and the second phases. The DRX nucleation weakened the texture intensity, and the further growth caused the more scattered basal texture. The hot-processing maps at different strains were also measured and the optimal hot-processing range could be confirmed at the deformation temperatures of 600~723 K and the strain rates of 0.018~0.563 s^(-1). Based on the optimum hot-processing range, a suitable extrusion parameter was considered as 603 K and 0.1 mm/s and the as-extruded alloy in this parameter exhibited a good strength-ductility synergy(yield strength of ~ 232.1 MPa, ultimate strength of ~ 278.2 MPa and elongation-to-failure of ~ 20.1%). Finally, the strengthening-plasticizing mechanisms and the relationships between the DRXed grain size, yield strength and extrusion parameters were analyzed.展开更多
Few studies were reported on the phases'relationships of AE44(Mg-4.0Al-4.1RE-0.3Mn,wt.%)and its composites.In this work,AE44 alloy and Saffil(6-Al2O3)/AE44 Metal matrix composite(MMC)were both prepared by slow sho...Few studies were reported on the phases'relationships of AE44(Mg-4.0Al-4.1RE-0.3Mn,wt.%)and its composites.In this work,AE44 alloy and Saffil(6-Al2O3)/AE44 Metal matrix composite(MMC)were both prepared by slow shot high pressure die casting(SS-HPDC)technology and their phase constitutions were all studied in detail using experimental techniques combined with CALPHAD(Calculation of Phase Diagram)modeling.The results revealed that the alloy consists of the a-Mg matrix,A1hRE3 intermetallic phase,and one trace phase AI3RE,while the composite contains five major phases:a-Mg,5-AI2O3,AI3RE,MgO and Mg2Si.and two trace phases of A12RE and AI11RE3,respectively.A1hRE3 is partly derived from ALRE,while A13RE is a product of the peritectoid reaction between the two precipitates.The presence of MgO and Mg2Si is due to the interfacial reaction between the SiO2 binder in the fiber preforms and the molten magnesium during infiltration.The use of SiO2 binder in the preform manufacturing was limited/minimized to reduce the MgO formation in the MMC casting process,which can be detrimental to the fatigue performance of the MMC materials.展开更多
This invited mini-review briefly summarizes procedures and challenges of measuring receptor occupancy with positron emission tomography. Instead of describing the detailed analytic procedures of in vivo ligand-recepto...This invited mini-review briefly summarizes procedures and challenges of measuring receptor occupancy with positron emission tomography. Instead of describing the detailed analytic procedures of in vivo ligand-receptor imaging, the authors provide a pragmatic alJproach, along with personal perspectives, for conducting positron emission tomography imaging for receptor occupancy, and systematically elucidate the mathematics of receptor occupancy calculations in practical ways that can be understood with elementary algebra. The authors also share insights regarding positron emission tomography imaging for receptor occupancy to facilitate applications for the development of drugs targeting receptors in the central nervous system.展开更多
As bifunctional oxygen evolution/reduction electrocatalysts,transition-metal-based single-atom-doped nitrogen-carbon(NC)matrices are promising successors of the corresponding noblemetal-based catalysts,offering the ad...As bifunctional oxygen evolution/reduction electrocatalysts,transition-metal-based single-atom-doped nitrogen-carbon(NC)matrices are promising successors of the corresponding noblemetal-based catalysts,offering the advantages of ultrahigh atom utilization effciency and surface active energy.However,the fabrication of such matrices(e.g.,well-dispersed single-atom-doped M-N4/NCs)often requires numerous steps and tedious processes.Herein,ultrasonic plasma engineering allows direct carbonization in a precursor solution containing metal phthalocyanine and aniline.When combining with the dispersion effect of ultrasonic waves,we successfully fabricated uniform single-atom M-N4(M=Fe,Co)carbon catalysts with a production rate as high as 10 mg min-1.The Co-N4/NC presented a bifunctional potential drop ofΔE=0.79 V,outperforming the benchmark Pt/C-Ru/C catalyst(ΔE=0.88 V)at the same catalyst loading.Theoretical calculations revealed that Co-N4 was the major active site with superior O2 adsorption-desorption mechanisms.In a practical Zn-air battery test,the air electrode coated with Co-N4/NC exhibited a specific capacity(762.8 mAh g(-1))and power density(101.62 mW cm^(-2)),exceeding those of Pt/C-Ru/C(700.8 mAh g^(-1) and 89.16 mW cm^(-2),respectively)at the same catalyst loading.Moreover,for Co-N4/NC,the potential difference increased from 1.16 to 1.47 V after 100 charge-discharge cycles.The proposed innovative and scalable strategy was concluded to be well suited for the fabrication of single-atom-doped carbons as promising bifunctional oxygen evolution/reduction electrocatalysts for metal-air batteries.展开更多
Acne vulgaris is the most common skin condition associated with inflammation of the pilosebaceous unit and affects all ethnic and age groups, independent of sex, nationality, or socioeconomic status. Treatment usually...Acne vulgaris is the most common skin condition associated with inflammation of the pilosebaceous unit and affects all ethnic and age groups, independent of sex, nationality, or socioeconomic status. Treatment usually includes oral and/or physical and/or topical interventions—the last can be obtained through commercial preparations in fixed doses or as compounded creams/gels, with personalized qualitative and quantitative composition, to be unique to each patient. In this sense, ready-to-use vehicles play an important role as a timesaving strategy and to ensure maximum results from the treatment. In this paper, we present Cleoderm<sup>TM</sup> Clarifying Cream, a ready-to-use, functional semisolid vehicle for acne treatments and topical products for oily skin, to be used by compounding pharmacies. It contains ingredients that can potentiate the effects of the active ingredients added, and has a light and pleasant skin feel. The current body of evidence shows that Cleoderm<sup>TM</sup> Clarifying Cream can be an important strategy for compounding personalized acne treatments due to its multiple positive roles on decreasing sebum production, lipid peroxidation, and reactive oxygen species, inhibition of <em>Cutibacterium acnes</em> proliferation, and control of inflammation.展开更多
Introduction: Fatigue is an important fibromyalgia (FM) symptom, but existing measures of fatigue are unlikely to meet regulatory standards for clinical trial use. We describe the development and validation of the Dai...Introduction: Fatigue is an important fibromyalgia (FM) symptom, but existing measures of fatigue are unlikely to meet regulatory standards for clinical trial use. We describe the development and validation of the Daily Diary of Fatigue Symptoms—Fibromyalgia (DFS-Fibro), a 24-hour recall, patient-reported outcome (PRO) measure of fatigue in FM that is administered electronically (ePRO). Methods: There were 3 phases of work: 1) item generation based on concept elicitation interviews with FM patients, with clinical relevance confirmed by expert clinician review;2) pilot testing/cognitive debriefing interviews with FM patients;and 3) psychometric validation using data from a methodology study with 145 FM patients. The measure was finalised based on both qualitative and quantitative findings. Results: Twenty-three items were generated in phase 1, some minor revisions were made following the pilot testing and cognitive debriefing (phase 2) but none were deleted. All patients found the measure easy to understand and use. Item reduction was conducted taking into account both the initial psychometric data and the earlier qualitative research, resulting in a final 5 item measure of the “symptom” of fatigue. The 5-item DFS-Fibro had very high internal consistency (alpha = 0.99), and strong test-re-test reliability (r > 0.84), convergent validity and known-groups validity. Conclusion: The DFS-Fibro has strong psychometric properties and strong face and content validity for the measurement of fatigue in FM.展开更多
Weed competition in the potato crop could cause up to a 95% yield reduction depending on the variety, the weed species and the competition period. In this work the effect of Clomazone (Command 36 CS<sup>®...Weed competition in the potato crop could cause up to a 95% yield reduction depending on the variety, the weed species and the competition period. In this work the effect of Clomazone (Command 36 CS<sup>®</sup>), when applied alone or in combination with Metribuzin (Sencorex<sup>®</sup> 48) upon grass and broad-leaved weeds was assessed. The work was carried out under the environmental conditions of the Argentinian Pampas, where close to 50% of the potatoes produced in the country are grown. The field trial was performed during the spring-summer crop, season 2008/09, with cv. Innovator, in a completely randomized design of the following treatments: (a) control, without weed control;(b) Clomazone 1.6 l·ha<sup>-1</sup>;(c) Clomazone 2.0 l·ha<sup>-1</sup>;(d) Clomazone 1 l·ha<sup>-1</sup> + Metribuzin 0.75 l·ha<sup>-1</sup>;(e) Clomazone 1.6 l·ha<sup>-1</sup> + Metribuzin 0.5 l·ha<sup>-1</sup>;and (f) Metribuzin 1.35 l·ha<sup>-1</sup>. Treatment effectiveness (TE), crop competition level (CCL) and weed suppression index (WSI) were assessed at 38, 53 and 72 days after planting (DAP), while yield and quality were also evaluated, following industry protocols. In those treatments were Clomazone was used alone, at 2 l·ha<sup>-1</sup>, or combined (Clomazone 1 l·ha<sup>-1</sup> + Metribuzin 0.75 l·ha<sup>-1</sup>), a higher yield was observed. Besides, a high correlation between TE, WSI and tuber yield was also achieved. Clomazone improved TE, CCL and WSI, which was not only reflected in higher tuber yields, but also on better tuber quality.展开更多
Since the automatic dishwasher became a very common household appliance,some negative surface modifications with dishes can happen.This paper is recapping main risk factors for glass and décor corrosion after lon...Since the automatic dishwasher became a very common household appliance,some negative surface modifications with dishes can happen.This paper is recapping main risk factors for glass and décor corrosion after long term washing in the dishwasher.The different possibilities for a detergent providing protection of glassware are pointed out.Additionally,the impacts on material care due to the US and EU-phosphate ban in dishwasher detergents are discussed.展开更多
Objective: To identify predictors of ascites collected prior to the hCG administration in patients undergoing IVF/ICSI treatment at moderate risk of developing moderate/severe ovarian hyperstimulation syndrome (OHSS),...Objective: To identify predictors of ascites collected prior to the hCG administration in patients undergoing IVF/ICSI treatment at moderate risk of developing moderate/severe ovarian hyperstimulation syndrome (OHSS), and, based on these predictors, develop a nomogram for estimation of the probability of presence of ascites. Methods and Materials: Data were derived from 53 patients with 20 - 30 follicles ≥10 mmat end of stimulation. All patients received a single dose of hCG (250 mg) to trigger final follicular maturation when ≥2 follicles of ≥18 mmwere observed. Transvaginal ultrasound to measure ascites (total amount of peritoneal fluid ≥9 cm2inlithotomy position) was performed 2, 5 and 8 days after the hCG administration. Associations between clinical, sonographic and endocrinological variables recorded prior to the hCG administration and presence of ascites were analyzed by univariable and multivariable logistic regression. Results: Thirty-four patients (64%) had ultrasonic evidence of ascites. The multivariable analysis identified the total number of follicles [OR 1.29 (95% CI: 1.02 - 1.69, P = 0.043)], the ovarian volume [OR 1.05 (95% CI: 1.00 - 1.11, P = 0.047)] and BMI [OR 0.76 (95% CI: 0.56 - 0.99, P = 0.053)] as predictors of ascites (AUC = 0.825). A nomogram (PROFET) was designed with these three variables for individual prediction of the probability of development of ascites. Conclusions: This pilot investigation indicates that the risk of peritoneal fluid accumulation in IVF/ICSI patients at moderate risk of developing moderate/severe OHSS is influenced by the number of follicles and the ovarian volume on the day of hCG administration as well as the BMI.展开更多
基金supported partly by the Fundamental Research Funds for Central Universities(No.06500203 and No.00007735).
文摘China is currently vigorously implementing the“energy conservation and emission reduction”and“dual carbon”strategies.As the most resource-advantaged light metal material in China,Magnesium(Mg)alloy is progressively expanding its application in automobile,rail transportation,aerospace,medical,and electronic products.Chongqing University,Shanghai Jiaotong University,and Australian National University have conducted extensive research on the preparation,properties,and processes of Mg alloys.In the past 20 years,the proportion of Mg alloy in the automotive industry has gradually expanded,whereas currently the design and development of Mg alloy parts for automobiles has rarely been reported.Thus,the application models and typical parts cases of Mg alloy are summarized mainly from the four systems of the whole vehicle(body system,chassis system,powertrain system,interior,and exterior system).Subsequently,two actual original equipment manufacturers(OEM)cases are used to introduce the development logic of reliable die-cast Mg alloy,including forward design,formability analysis,process design analysis,structural redesign,manufacturing,and testing,aiming to share the methods,processes,and focus of attention of automotive OEMs for developing Mg alloy parts to enhance the confidence and motivation of applying Mg alloy in automotive field.Eventually,the multiple challenges faced by Mg alloy materials are sorted out and how to face these challenges are discussed.National policies and regulations,environmental protection and energy saving,and consumer demand will continue to promote the application of Mg.
基金funded by the Postgraduate Research & Practice Innovation Program of Jiangsu Province (No.SJCX22_1720)the National Natural Science Foundation of China (No.51901204)+1 种基金the Chongqing Science and Technology Commission (Nos.cstc2020jcyj-msxmX0184 and cstc2019jscx-mbdxX0031)the University Innovation Research Group of Chongqing (No.CXQT20023)。
文摘The fundamental research on thermo-mechanical conditions provides an experimental basis for high-performance Mg-Al-Ca-Mn alloys.However, there is a lack of systematical investigation for this series alloys on the hot-deformation kinetics and extrusion parameter optimization. Here, the flow behavior, constitutive model, dynamic recrystallization(DRX) kinetic model and processing map of a dilute rare-earth free Mg-1.3Al-0.4Ca-0.4Mn(AXM100, wt.%) alloy were studied under different hot-compressive conditions. In addition, the extrusion parameter optimization of this alloy was performed based on the hot-processing map. The results showed that the conventional Arrhenius-type strain-related constitutive model only worked well for the flow curves at high temperatures and low strain rates. In comparison, using the machine learning assisted model(support vector regression, SVR) could effectively improve the accuracy between the predicted and experimental values. The DRX kinetic model was established, and a typical necklace-shaped structure preferentially occurred at the original grain boundaries and the second phases. The DRX nucleation weakened the texture intensity, and the further growth caused the more scattered basal texture. The hot-processing maps at different strains were also measured and the optimal hot-processing range could be confirmed at the deformation temperatures of 600~723 K and the strain rates of 0.018~0.563 s^(-1). Based on the optimum hot-processing range, a suitable extrusion parameter was considered as 603 K and 0.1 mm/s and the as-extruded alloy in this parameter exhibited a good strength-ductility synergy(yield strength of ~ 232.1 MPa, ultimate strength of ~ 278.2 MPa and elongation-to-failure of ~ 20.1%). Finally, the strengthening-plasticizing mechanisms and the relationships between the DRXed grain size, yield strength and extrusion parameters were analyzed.
基金This work was co-funded by,The National Key Research and Development Program of China(NO.2016YFB0301002)and General Motors Global Research and Development.
文摘Few studies were reported on the phases'relationships of AE44(Mg-4.0Al-4.1RE-0.3Mn,wt.%)and its composites.In this work,AE44 alloy and Saffil(6-Al2O3)/AE44 Metal matrix composite(MMC)were both prepared by slow shot high pressure die casting(SS-HPDC)technology and their phase constitutions were all studied in detail using experimental techniques combined with CALPHAD(Calculation of Phase Diagram)modeling.The results revealed that the alloy consists of the a-Mg matrix,A1hRE3 intermetallic phase,and one trace phase AI3RE,while the composite contains five major phases:a-Mg,5-AI2O3,AI3RE,MgO and Mg2Si.and two trace phases of A12RE and AI11RE3,respectively.A1hRE3 is partly derived from ALRE,while A13RE is a product of the peritectoid reaction between the two precipitates.The presence of MgO and Mg2Si is due to the interfacial reaction between the SiO2 binder in the fiber preforms and the molten magnesium during infiltration.The use of SiO2 binder in the preform manufacturing was limited/minimized to reduce the MgO formation in the MMC casting process,which can be detrimental to the fatigue performance of the MMC materials.
文摘This invited mini-review briefly summarizes procedures and challenges of measuring receptor occupancy with positron emission tomography. Instead of describing the detailed analytic procedures of in vivo ligand-receptor imaging, the authors provide a pragmatic alJproach, along with personal perspectives, for conducting positron emission tomography imaging for receptor occupancy, and systematically elucidate the mathematics of receptor occupancy calculations in practical ways that can be understood with elementary algebra. The authors also share insights regarding positron emission tomography imaging for receptor occupancy to facilitate applications for the development of drugs targeting receptors in the central nervous system.
基金supported by Global Frontier Program through the Global Frontier Hybrid Interface materials(GFHIM)of the National Research Foundation of Korea(NRF)funded by the ministry of science,ICT and Future Planning(2013M3A6B1078874)co-supported by Busan Innovation Institute of Industry,Science&Technology Planning(BISTEP)+1 种基金the financial support of Federal Ministry of Education and Research(BMBF)under the“Make Our Planet Great Again-German Research Initiative”(MOPGAGRI),57429784implemented by the German Academic Exchange Service Deutscher Akademischer Austauschdienst(DAAD)。
文摘As bifunctional oxygen evolution/reduction electrocatalysts,transition-metal-based single-atom-doped nitrogen-carbon(NC)matrices are promising successors of the corresponding noblemetal-based catalysts,offering the advantages of ultrahigh atom utilization effciency and surface active energy.However,the fabrication of such matrices(e.g.,well-dispersed single-atom-doped M-N4/NCs)often requires numerous steps and tedious processes.Herein,ultrasonic plasma engineering allows direct carbonization in a precursor solution containing metal phthalocyanine and aniline.When combining with the dispersion effect of ultrasonic waves,we successfully fabricated uniform single-atom M-N4(M=Fe,Co)carbon catalysts with a production rate as high as 10 mg min-1.The Co-N4/NC presented a bifunctional potential drop ofΔE=0.79 V,outperforming the benchmark Pt/C-Ru/C catalyst(ΔE=0.88 V)at the same catalyst loading.Theoretical calculations revealed that Co-N4 was the major active site with superior O2 adsorption-desorption mechanisms.In a practical Zn-air battery test,the air electrode coated with Co-N4/NC exhibited a specific capacity(762.8 mAh g(-1))and power density(101.62 mW cm^(-2)),exceeding those of Pt/C-Ru/C(700.8 mAh g^(-1) and 89.16 mW cm^(-2),respectively)at the same catalyst loading.Moreover,for Co-N4/NC,the potential difference increased from 1.16 to 1.47 V after 100 charge-discharge cycles.The proposed innovative and scalable strategy was concluded to be well suited for the fabrication of single-atom-doped carbons as promising bifunctional oxygen evolution/reduction electrocatalysts for metal-air batteries.
文摘Acne vulgaris is the most common skin condition associated with inflammation of the pilosebaceous unit and affects all ethnic and age groups, independent of sex, nationality, or socioeconomic status. Treatment usually includes oral and/or physical and/or topical interventions—the last can be obtained through commercial preparations in fixed doses or as compounded creams/gels, with personalized qualitative and quantitative composition, to be unique to each patient. In this sense, ready-to-use vehicles play an important role as a timesaving strategy and to ensure maximum results from the treatment. In this paper, we present Cleoderm<sup>TM</sup> Clarifying Cream, a ready-to-use, functional semisolid vehicle for acne treatments and topical products for oily skin, to be used by compounding pharmacies. It contains ingredients that can potentiate the effects of the active ingredients added, and has a light and pleasant skin feel. The current body of evidence shows that Cleoderm<sup>TM</sup> Clarifying Cream can be an important strategy for compounding personalized acne treatments due to its multiple positive roles on decreasing sebum production, lipid peroxidation, and reactive oxygen species, inhibition of <em>Cutibacterium acnes</em> proliferation, and control of inflammation.
文摘Introduction: Fatigue is an important fibromyalgia (FM) symptom, but existing measures of fatigue are unlikely to meet regulatory standards for clinical trial use. We describe the development and validation of the Daily Diary of Fatigue Symptoms—Fibromyalgia (DFS-Fibro), a 24-hour recall, patient-reported outcome (PRO) measure of fatigue in FM that is administered electronically (ePRO). Methods: There were 3 phases of work: 1) item generation based on concept elicitation interviews with FM patients, with clinical relevance confirmed by expert clinician review;2) pilot testing/cognitive debriefing interviews with FM patients;and 3) psychometric validation using data from a methodology study with 145 FM patients. The measure was finalised based on both qualitative and quantitative findings. Results: Twenty-three items were generated in phase 1, some minor revisions were made following the pilot testing and cognitive debriefing (phase 2) but none were deleted. All patients found the measure easy to understand and use. Item reduction was conducted taking into account both the initial psychometric data and the earlier qualitative research, resulting in a final 5 item measure of the “symptom” of fatigue. The 5-item DFS-Fibro had very high internal consistency (alpha = 0.99), and strong test-re-test reliability (r > 0.84), convergent validity and known-groups validity. Conclusion: The DFS-Fibro has strong psychometric properties and strong face and content validity for the measurement of fatigue in FM.
文摘Weed competition in the potato crop could cause up to a 95% yield reduction depending on the variety, the weed species and the competition period. In this work the effect of Clomazone (Command 36 CS<sup>®</sup>), when applied alone or in combination with Metribuzin (Sencorex<sup>®</sup> 48) upon grass and broad-leaved weeds was assessed. The work was carried out under the environmental conditions of the Argentinian Pampas, where close to 50% of the potatoes produced in the country are grown. The field trial was performed during the spring-summer crop, season 2008/09, with cv. Innovator, in a completely randomized design of the following treatments: (a) control, without weed control;(b) Clomazone 1.6 l·ha<sup>-1</sup>;(c) Clomazone 2.0 l·ha<sup>-1</sup>;(d) Clomazone 1 l·ha<sup>-1</sup> + Metribuzin 0.75 l·ha<sup>-1</sup>;(e) Clomazone 1.6 l·ha<sup>-1</sup> + Metribuzin 0.5 l·ha<sup>-1</sup>;and (f) Metribuzin 1.35 l·ha<sup>-1</sup>. Treatment effectiveness (TE), crop competition level (CCL) and weed suppression index (WSI) were assessed at 38, 53 and 72 days after planting (DAP), while yield and quality were also evaluated, following industry protocols. In those treatments were Clomazone was used alone, at 2 l·ha<sup>-1</sup>, or combined (Clomazone 1 l·ha<sup>-1</sup> + Metribuzin 0.75 l·ha<sup>-1</sup>), a higher yield was observed. Besides, a high correlation between TE, WSI and tuber yield was also achieved. Clomazone improved TE, CCL and WSI, which was not only reflected in higher tuber yields, but also on better tuber quality.
文摘Since the automatic dishwasher became a very common household appliance,some negative surface modifications with dishes can happen.This paper is recapping main risk factors for glass and décor corrosion after long term washing in the dishwasher.The different possibilities for a detergent providing protection of glassware are pointed out.Additionally,the impacts on material care due to the US and EU-phosphate ban in dishwasher detergents are discussed.
文摘Objective: To identify predictors of ascites collected prior to the hCG administration in patients undergoing IVF/ICSI treatment at moderate risk of developing moderate/severe ovarian hyperstimulation syndrome (OHSS), and, based on these predictors, develop a nomogram for estimation of the probability of presence of ascites. Methods and Materials: Data were derived from 53 patients with 20 - 30 follicles ≥10 mmat end of stimulation. All patients received a single dose of hCG (250 mg) to trigger final follicular maturation when ≥2 follicles of ≥18 mmwere observed. Transvaginal ultrasound to measure ascites (total amount of peritoneal fluid ≥9 cm2inlithotomy position) was performed 2, 5 and 8 days after the hCG administration. Associations between clinical, sonographic and endocrinological variables recorded prior to the hCG administration and presence of ascites were analyzed by univariable and multivariable logistic regression. Results: Thirty-four patients (64%) had ultrasonic evidence of ascites. The multivariable analysis identified the total number of follicles [OR 1.29 (95% CI: 1.02 - 1.69, P = 0.043)], the ovarian volume [OR 1.05 (95% CI: 1.00 - 1.11, P = 0.047)] and BMI [OR 0.76 (95% CI: 0.56 - 0.99, P = 0.053)] as predictors of ascites (AUC = 0.825). A nomogram (PROFET) was designed with these three variables for individual prediction of the probability of development of ascites. Conclusions: This pilot investigation indicates that the risk of peritoneal fluid accumulation in IVF/ICSI patients at moderate risk of developing moderate/severe OHSS is influenced by the number of follicles and the ovarian volume on the day of hCG administration as well as the BMI.
基金Project(11727802)supported by the National Natural Science Foundation of ChinaProjects(2018CDJSK04XK09,106112017CDJQJ328840)supported by the Fundamental Research Funds for the Central Universities,China。