Dendrobium,orchid,is a traditional Chinese herb medicine applied extensively as tonic and precious food for thousands of years recorded in ancient Chinese medical book"Shen Nong’s Materia Medica".It’s well...Dendrobium,orchid,is a traditional Chinese herb medicine applied extensively as tonic and precious food for thousands of years recorded in ancient Chinese medical book"Shen Nong’s Materia Medica".It’s well known that bioactivities are usually related to the ingredients’basis.Based on the previous research,Dendrobium species contain amino acid,sesquiterpenoids,alkaloids and polysaccharides.As the bioactive substances,carbohydrate shows extensive activities in antitumor,antiglycation,immune-enhancing,antivirus,antioxidant,antitumor and etc.Therefore,as the main biologically active substance,the exact structures and latent activities of polysaccharides from Dendrobium species are widely focused on.In this review,we focus on the advancements of extraction methods and diversity of structures and bioactivities of polysaccharides obtained from Dendrobium species.展开更多
Alzheimer's disease(AD) is a neurodegenerative disorder characterized by the loss of patients' memory and their cognitive abilities and the mechanism is not completely clear. Although a variety of drugs have b...Alzheimer's disease(AD) is a neurodegenerative disorder characterized by the loss of patients' memory and their cognitive abilities and the mechanism is not completely clear. Although a variety of drugs have been approved for the AD treatment, substances which can prevent and cure AD are still in great need. The effect of polysaccharides from traditional Chinese medicine(TCM) on anti-AD has gained great progress and attained more and more attention in recent years. In this review, research advances in TCM-polysaccharides on AD made in this decade are summarized.展开更多
基金supported by Shanghai Committee of Science and Technology(No.15495800300)the State Key Program of National Natural Science Foundation of China(No.31230022)+1 种基金the Program of Shanghai Subject Chief Scientist(No.16XD1404500)the National Natural Science Foundation of China(No.31670814)
文摘Dendrobium,orchid,is a traditional Chinese herb medicine applied extensively as tonic and precious food for thousands of years recorded in ancient Chinese medical book"Shen Nong’s Materia Medica".It’s well known that bioactivities are usually related to the ingredients’basis.Based on the previous research,Dendrobium species contain amino acid,sesquiterpenoids,alkaloids and polysaccharides.As the bioactive substances,carbohydrate shows extensive activities in antitumor,antiglycation,immune-enhancing,antivirus,antioxidant,antitumor and etc.Therefore,as the main biologically active substance,the exact structures and latent activities of polysaccharides from Dendrobium species are widely focused on.In this review,we focus on the advancements of extraction methods and diversity of structures and bioactivities of polysaccharides obtained from Dendrobium species.
基金supported by National Natural Science Foundation of China(NSFC)(No.31230022)Shanghai Outstanding Academic Leaders Program(No.16XD1404500)
文摘Alzheimer's disease(AD) is a neurodegenerative disorder characterized by the loss of patients' memory and their cognitive abilities and the mechanism is not completely clear. Although a variety of drugs have been approved for the AD treatment, substances which can prevent and cure AD are still in great need. The effect of polysaccharides from traditional Chinese medicine(TCM) on anti-AD has gained great progress and attained more and more attention in recent years. In this review, research advances in TCM-polysaccharides on AD made in this decade are summarized.
